14
F. B. SHORLAND
tive structure would require inositol diphosphate among the products
of hydrolysis, but this substance was not found.
OH OH
I I
OH OH
O
O
CH—CH
CH 2 —CH—CH 2 —0—P—O—CH 2 —CH 2 —NH—P—O—CH
CH—O
A,x
- ^
OH
OH
CH—CH
I !
OH OH trisaccharide
or
disaccharide
plus
arabinose
(IX)
4. Sphingolipids
These compounds are derivatives of the base sphingosine:
CH 3 (CH 2 )i 2 · CH=CH · CH(OH) · CH(NH 2 ) · CH 2 · OH
In sphingomyelin (X) the amino group is attached to a fatty acid,
lignoceric acid, and the terminal alcoholic group to phosphorylcholine.
H
CH 3 (CH 2 )i 2 CH=CH · CH—C
CH 2
I
I
I
OH NH
O
I
I
CO 0=P · OH
I
I
R
O · CH 2 · CH 2 N(CH 3 ) 3
OH
(X)
In cerebrosides the terminal alcoholic group of sphingosine is united
with galactose (or other hexose), and the fatty acid radical is united
as the amide (XI).
CH 3 · (CH,)« · CH=CH · CH(OH) · CH · CH 2 · O · CH
I
I
NH
CH(OH)
CO
CH(OH) 0
R
CH(OH)
CH CH 2 OH
(XI)