S U B J E C T I N D E X
749
Glucocorticosteroids,
zona fasciculata and, 603
Glucokinase,
growth hormone and, 595, 601
Glucosamine,
acetyl C o A , and, 378
and cell aggregation, 501
derived from glucose, 112, 377
estimation of, 363
and mucopolysaccharides, 356-7, 377
in organ cultures o f bone, 371
Glucosamine-6-phosphate-acety lase, 378
Glucosamine-6-phosphate
deaminase,
378
Glucose,
and amino-acid formation, 112, 115,
250, 283, 2 8 7 - 9 , 299, 380
and amino-acid sparing, 249
bone rudiments and, 129
concentration and glycolysis, 259-60
concentration and polysaccharide production, 373
and C o A , 241
and culture o f eggs, 5 7 6 - 7 , 580, 583
and culture o f lens, 80
and differentiation o f somites, 569
epidermis and, 27
and growth o f blastoderms, 566, 583
growth without, 257
Hensen's node and concentration of, 566
insulin and, 117, 5 9 3 - 4
and mitotic rate, 5 9 3 - 4
as mucopolysaccharide precursor, 377,
380
and neuralization, 543
neural tissues and, 27
and nucleic acid synthesis, 255, 380
in organ cultures, 79, 81
polymerization of, 241
radioactive, 250, 299, 377-80
requirement for, 27, 72, 2 4 4 - 6
and respiration, 251, 254, 259
in synthetic media, 112, 128, 280
utilization of, 3, 112, 117, 2 4 4 , 2 4 8 - 5 1 ,
260, 593
utilization and hexokinase, 262
utilization and polysaccharide production, 374
Glucose-6-phosphatase,
in epithelial cells, 266
Glucose-6-phosphate,
insulin and, 594
Glucose-6-phosphate dehydrogenase,
in cartilage, 648
Glucuronic acid, 246
instability of, 3 6 3 - 4
and mucopolysaccharides, 3 5 6 - 7 ,
synthesis of, 377
and vitamin C, 682
^-glucuronidase,
induction of, 264
Glutamic acid (glutamate),
and amino-acid formation, 2 8 7 - 9
and cell strains, 114, 2 8 0 - 1 , 286
in collagen, 163
and differentiation, 5 6 8 - 9
formation of, 255
from glucose, 249-50, 299
glutamine from, 280, 287, 301
and heart tissue, 299
inessential for b o n e cells, 163
L-strain and, 114
and myoblasts, 304
and oxaloacetate, 648
precursors of, 249-50, 288, 299
and prostate, 304
and requirement for glutamine, 2 8 6 - 7
as source o f N H 2 , 288
Glutamic dehydrogenase,
absent from osteoclasts, 6 4 8 - 9
Glutamine,
and amino-acid synthesis, 283, 2 8 7 - 8
and b o n e rudiments, 129, 301
and cell strains, 114, 279-81
and differentiation o f somites, 569
in fresh tissues and cell lines, 303
from glutamic acid, 280, 287, 301
and heart tissue, 299
instability of, in media, 120
precursors of, 2 8 7 - 9
as precursor o f nucleic acid, 287
as precursor o f protein, 287
as population-dependent metabolite,
286
as supplement to Eagle's medium,
110, 280
and synthesis o f hexosamine, 3 7 7 - 8
-synthetase, 280, 295, 299, 302
Glutathione ( G S H ) ,
and cell division, 685
and cloning o f H e L a cells, 684
and differentiation o f somites, 568
in embryo juice, 684
as oxygen carrier, 82
749
Glucocorticosteroids,
zona fasciculata and, 603
Glucokinase,
growth hormone and, 595, 601
Glucosamine,
acetyl C o A , and, 378
and cell aggregation, 501
derived from glucose, 112, 377
estimation of, 363
and mucopolysaccharides, 356-7, 377
in organ cultures o f bone, 371
Glucosamine-6-phosphate-acety lase, 378
Glucosamine-6-phosphate
deaminase,
378
Glucose,
and amino-acid formation, 112, 115,
250, 283, 2 8 7 - 9 , 299, 380
and amino-acid sparing, 249
bone rudiments and, 129
concentration and glycolysis, 259-60
concentration and polysaccharide production, 373
and C o A , 241
and culture o f eggs, 5 7 6 - 7 , 580, 583
and culture o f lens, 80
and differentiation o f somites, 569
epidermis and, 27
and growth o f blastoderms, 566, 583
growth without, 257
Hensen's node and concentration of, 566
insulin and, 117, 5 9 3 - 4
and mitotic rate, 5 9 3 - 4
as mucopolysaccharide precursor, 377,
380
and neuralization, 543
neural tissues and, 27
and nucleic acid synthesis, 255, 380
in organ cultures, 79, 81
polymerization of, 241
radioactive, 250, 299, 377-80
requirement for, 27, 72, 2 4 4 - 6
and respiration, 251, 254, 259
in synthetic media, 112, 128, 280
utilization of, 3, 112, 117, 2 4 4 , 2 4 8 - 5 1 ,
260, 593
utilization and hexokinase, 262
utilization and polysaccharide production, 374
Glucose-6-phosphatase,
in epithelial cells, 266
Glucose-6-phosphate,
insulin and, 594
Glucose-6-phosphate dehydrogenase,
in cartilage, 648
Glucuronic acid, 246
instability of, 3 6 3 - 4
and mucopolysaccharides, 3 5 6 - 7 ,
synthesis of, 377
and vitamin C, 682
^-glucuronidase,
induction of, 264
Glutamic acid (glutamate),
and amino-acid formation, 2 8 7 - 9
and cell strains, 114, 2 8 0 - 1 , 286
in collagen, 163
and differentiation, 5 6 8 - 9
formation of, 255
from glucose, 249-50, 299
glutamine from, 280, 287, 301
and heart tissue, 299
inessential for b o n e cells, 163
L-strain and, 114
and myoblasts, 304
and oxaloacetate, 648
precursors of, 249-50, 288, 299
and prostate, 304
and requirement for glutamine, 2 8 6 - 7
as source o f N H 2 , 288
Glutamic dehydrogenase,
absent from osteoclasts, 6 4 8 - 9
Glutamine,
and amino-acid synthesis, 283, 2 8 7 - 8
and b o n e rudiments, 129, 301
and cell strains, 114, 279-81
and differentiation o f somites, 569
in fresh tissues and cell lines, 303
from glutamic acid, 280, 287, 301
and heart tissue, 299
instability of, in media, 120
precursors of, 2 8 7 - 9
as precursor o f nucleic acid, 287
as precursor o f protein, 287
as population-dependent metabolite,
286
as supplement to Eagle's medium,
110, 280
and synthesis o f hexosamine, 3 7 7 - 8
-synthetase, 280, 295, 299, 302
Glutathione ( G S H ) ,
and cell division, 685
and cloning o f H e L a cells, 684
and differentiation o f somites, 568
in embryo juice, 684
as oxygen carrier, 82