740
S U B J E C T I N D E X
Contamination,
of cultures b y organisms, 21
of cultures b y other cells, 34
of dispersive enzymes, 56
of " p u r e " chemicals, 112
of " p u r e " strains, 8, 170
Contractility,
o f cardiac muscle, 465
Copper,
requirement for, 111, 282
Cornea,
detachment o f epithelium, 51
histamine on epithelium of, 51
mitosis in, 672
vitamin A and, 663, 672
Cornification, see Keratinization
Corpus luteum,
extracts and iris, 616
Corticosteroids (see also specific hormones)
and cell division, 607, 612, 615
and chondroitin sulphate, 612
and D N A in cartilage, 612
and endothelium, 615
and fluid transfer, 610
and growth o f fibroblasts, 607
and growth hormone, 615
and insulin, 615
and kidney function, 609-10, 686
and lymphocytes, 615
and m a m m a r y gland, 633, 638
in m e d i u m o f adrenal cultures, 604
and melanophores, 609, 615
and metabolism, 265, 615
Cortisol,
and m a m m a r y gland function, 127,
636, 6 3 8 - 9
Cortisone,
acetate, 607
on b o n e , 612, 615
o n cartilage, 612
and growth, 607
and growth hormone, 6 0 7 - 8
and insulin, 608
and lymphocytes, 6 0 8 - 9 , 612
and m a m m a r y glands, 6 3 5 - 6
and mast cells, 385
on muscle cells, 612, 614
on skin, 385
—sulphate, 607
—tricarallytate, 607
Cotton-wool,
in organ cultures, 74, 76
Cotyledons,
and vitamin C requirement o f peas,
682
" C o u p l i n g and uncoupling", 244, 263
Crabtree effect, 251, 259-60, 262
Critical mass,
for differentiation, 285
Culture vessels,
illustrations of, 30, 39, 61, 73, 554-5
seals for, 30, 38
Cyanide,
and
development o f blastoderms,
571-2
on growth and metabolism, 253
and mitosis, 215-16, 225, 253, 256
and reducing activity o f blastoderm,
567
Cystathionine, 287
Cysteamine, 215-16
Cysteine,
for cloning H e L a cells, 684
and differentiation o f somites, 568, 570
from glucose, 299
and growth o f tibia, 301
and keratinization, 26, 129, 470
loss of, to medium, 281
L-strain and, 114
as population-dependent metabolite,
287
and protease activity, 310
requirement for, b y cell strains, 279-81
and sulphate, 378
and synthesis o f cystine, 287
Cystine,
in Eagle's medium, 280
from glucose, 301
for gonads, 301
and heart tissue, 300-1, 303
and keratinization, 26, 129, 305-6,
470, 614
and kidney, 303
and liver, 303
loss of, to medium, 281
in mucous cells o f epidermis, 614
as population-dependent metabolite,
286-7
and prostate, 304
requirement for, b y cell strains, 279-81
substitutes for, 300
and syrinx, 301
synthesis of, 287
vitamin A , and utilization of, 3 0 5 - 6 , 6 6 8
S U B J E C T I N D E X
Contamination,
of cultures b y organisms, 21
of cultures b y other cells, 34
of dispersive enzymes, 56
of " p u r e " chemicals, 112
of " p u r e " strains, 8, 170
Contractility,
o f cardiac muscle, 465
Copper,
requirement for, 111, 282
Cornea,
detachment o f epithelium, 51
histamine on epithelium of, 51
mitosis in, 672
vitamin A and, 663, 672
Cornification, see Keratinization
Corpus luteum,
extracts and iris, 616
Corticosteroids (see also specific hormones)
and cell division, 607, 612, 615
and chondroitin sulphate, 612
and D N A in cartilage, 612
and endothelium, 615
and fluid transfer, 610
and growth o f fibroblasts, 607
and growth hormone, 615
and insulin, 615
and kidney function, 609-10, 686
and lymphocytes, 615
and m a m m a r y gland, 633, 638
in m e d i u m o f adrenal cultures, 604
and melanophores, 609, 615
and metabolism, 265, 615
Cortisol,
and m a m m a r y gland function, 127,
636, 6 3 8 - 9
Cortisone,
acetate, 607
on b o n e , 612, 615
o n cartilage, 612
and growth, 607
and growth hormone, 6 0 7 - 8
and insulin, 608
and lymphocytes, 6 0 8 - 9 , 612
and m a m m a r y glands, 6 3 5 - 6
and mast cells, 385
on muscle cells, 612, 614
on skin, 385
—sulphate, 607
—tricarallytate, 607
Cotton-wool,
in organ cultures, 74, 76
Cotyledons,
and vitamin C requirement o f peas,
682
" C o u p l i n g and uncoupling", 244, 263
Crabtree effect, 251, 259-60, 262
Critical mass,
for differentiation, 285
Culture vessels,
illustrations of, 30, 39, 61, 73, 554-5
seals for, 30, 38
Cyanide,
and
development o f blastoderms,
571-2
on growth and metabolism, 253
and mitosis, 215-16, 225, 253, 256
and reducing activity o f blastoderm,
567
Cystathionine, 287
Cysteamine, 215-16
Cysteine,
for cloning H e L a cells, 684
and differentiation o f somites, 568, 570
from glucose, 299
and growth o f tibia, 301
and keratinization, 26, 129, 470
loss of, to medium, 281
L-strain and, 114
as population-dependent metabolite,
287
and protease activity, 310
requirement for, b y cell strains, 279-81
and sulphate, 378
and synthesis o f cystine, 287
Cystine,
in Eagle's medium, 280
from glucose, 301
for gonads, 301
and heart tissue, 300-1, 303
and keratinization, 26, 129, 305-6,
470, 614
and kidney, 303
and liver, 303
loss of, to medium, 281
in mucous cells o f epidermis, 614
as population-dependent metabolite,
286-7
and prostate, 304
requirement for, b y cell strains, 279-81
substitutes for, 300
and syrinx, 301
synthesis of, 287
vitamin A , and utilization of, 3 0 5 - 6 , 6 6 8