S U B J E C T I N D E X
735
Cell division—continued
and differentiation, 469
energy metabolism of, 240, 244
errors in, 406
frequency of, 229
and glucose consumption, 5 9 3 - 4
and growth, 228
and growth hormone, 5 9 4 - 5 , 607
hanging-drop cultures and, 33
inhibitors o f 206, 2 2 8 - 9
insulin and, 593-4, 600, 635, 649
o f isolated cells, 66, 167
media for, 120
oestrogens and, 215, 616
in secondary aggregates, 519
sensitive periods of, 230
synchrony of, 229
testosterone and, in prostate, 623
thyroxin and, 6 4 0 - 2 , 644
X-rays and, 63, 206
Cell fractionation,
o f osteoblasts, 306
Cell interactions, 469, 471
and maintenance o f differentiation,
478
mucous coat and, 520
Cell movement (migration), 177-98
in aggregates, 493, 511, 519-23
alignment of, 151-2, 183
of amoebocytes, 179
in blastoderm, 560-1
in body, 145, 152, 177
and cell adhesion, 178-80, 183, 4 9 2 - 3
direction of, 184-6, 193-4, 196-7
and electrical stimuli, 190-1
embryo extract and, 31, 183
energy metabolism of, 240, 244
o n flat surface, 150, 178-9, 4 9 3 - 4
identification o f cells b y , 4 0 , 66
of lymphocytes, 148, 152, 179, 182, 184
in malignancy, 191
metabolic inhibitors o n , 253
o f nerve cells, 147-8
and mitosis, 153, 182
in organ cultures, 7 7 - 8
orientation of, 181-91
randomness in, 180, 193
recording of, 12, 33, 4 9 3 - 4
redox potentials and, 687
speed of, 3 1 , 181-3
starting and stopping of, 191-2
and synthesis o f cell substance, 256
in tissue cultures, 3 1 , 145-6, 177-8,
465
Celloidin,
as coating for coverslips, 3 1 - 3 2
Cellophane,
and blocking o f induction, 480
constricting effect of, 4 7 5 - 6
perforated, in flasks, 43, 104
for separating parabiotic strains, 116
as substratum for cells, 32, 3 9 - 4 0 , 149
Cell permeability,
dissociating agents and, 58
induction and, 543
lipids and, 153
and reducing activity o f cells, 567
Cell populations,
increase of, and generation time, 420
cell movement in, 193 et seq.
Cells,
adhesion of, 5 0 - 1 , 465, 489, 492
altered b y growth in monolayers, 515
clumping of, 195, 519-20
concentration of, and aggregation, 493
differential adhesiveness of, 498
differentiation o f single, 474
group relations among, 473
growth o f single cells, 474
isolation o f single, 4 7 - 9 , 63, 66
spreading of, 32
Cell strains (Cell lines: see also Pure
cultures),
adaptation in, 122
amino-acid requirements of, 114—15,
277-95
aneuploidy in, 125
compared with cells in vivo, 278, 466
compared with primary cultures, 121,
640
and hormones, 284, 293
idiosyncrasies of, 289
metabolic characteristics of, 266, 278,
303
morphological differences in sub-lines,
124
variant, 247, 289
and vitamin C , 684
Cell surface (membrane),
adaptation of, 168
altered b y contact with glass, 33
charge o n , 33, 69, 108, 164, 376
and collagen fibres, 60
composition of, 153, 158
735
Cell division—continued
and differentiation, 469
energy metabolism of, 240, 244
errors in, 406
frequency of, 229
and glucose consumption, 5 9 3 - 4
and growth, 228
and growth hormone, 5 9 4 - 5 , 607
hanging-drop cultures and, 33
inhibitors o f 206, 2 2 8 - 9
insulin and, 593-4, 600, 635, 649
o f isolated cells, 66, 167
media for, 120
oestrogens and, 215, 616
in secondary aggregates, 519
sensitive periods of, 230
synchrony of, 229
testosterone and, in prostate, 623
thyroxin and, 6 4 0 - 2 , 644
X-rays and, 63, 206
Cell fractionation,
o f osteoblasts, 306
Cell interactions, 469, 471
and maintenance o f differentiation,
478
mucous coat and, 520
Cell movement (migration), 177-98
in aggregates, 493, 511, 519-23
alignment of, 151-2, 183
of amoebocytes, 179
in blastoderm, 560-1
in body, 145, 152, 177
and cell adhesion, 178-80, 183, 4 9 2 - 3
direction of, 184-6, 193-4, 196-7
and electrical stimuli, 190-1
embryo extract and, 31, 183
energy metabolism of, 240, 244
o n flat surface, 150, 178-9, 4 9 3 - 4
identification o f cells b y , 4 0 , 66
of lymphocytes, 148, 152, 179, 182, 184
in malignancy, 191
metabolic inhibitors o n , 253
o f nerve cells, 147-8
and mitosis, 153, 182
in organ cultures, 7 7 - 8
orientation of, 181-91
randomness in, 180, 193
recording of, 12, 33, 4 9 3 - 4
redox potentials and, 687
speed of, 3 1 , 181-3
starting and stopping of, 191-2
and synthesis o f cell substance, 256
in tissue cultures, 3 1 , 145-6, 177-8,
465
Celloidin,
as coating for coverslips, 3 1 - 3 2
Cellophane,
and blocking o f induction, 480
constricting effect of, 4 7 5 - 6
perforated, in flasks, 43, 104
for separating parabiotic strains, 116
as substratum for cells, 32, 3 9 - 4 0 , 149
Cell permeability,
dissociating agents and, 58
induction and, 543
lipids and, 153
and reducing activity o f cells, 567
Cell populations,
increase of, and generation time, 420
cell movement in, 193 et seq.
Cells,
adhesion of, 5 0 - 1 , 465, 489, 492
altered b y growth in monolayers, 515
clumping of, 195, 519-20
concentration of, and aggregation, 493
differential adhesiveness of, 498
differentiation o f single, 474
group relations among, 473
growth o f single cells, 474
isolation o f single, 4 7 - 9 , 63, 66
spreading of, 32
Cell strains (Cell lines: see also Pure
cultures),
adaptation in, 122
amino-acid requirements of, 114—15,
277-95
aneuploidy in, 125
compared with cells in vivo, 278, 466
compared with primary cultures, 121,
640
and hormones, 284, 293
idiosyncrasies of, 289
metabolic characteristics of, 266, 278,
303
morphological differences in sub-lines,
124
variant, 247, 289
and vitamin C , 684
Cell surface (membrane),
adaptation of, 168
altered b y contact with glass, 33
charge o n , 33, 69, 108, 164, 376
and collagen fibres, 60
composition of, 153, 158