622
I L S E
L A S N I T Z K I
hormones, glands derived from 4-6-weeks-old mice underwent similar
changes to those found in castrated animals. In many alveoli the height
of the epithelium was reduced, the folding lost and the amount of
secretion diminished, while the stroma was increased, in both cells and
fibres, as compared with that seen in normal in vivo controls (Fig. 13).
FIG. 13. Explant of a prostate gland from a 6-week mouse grown for 10 days in medium
without added hormones. Note dilation of alveoli and low straight epithelium. Haematoxylin-eosin. x 120. (From Lasnitzki, 1951.)
FIG. 14. Comparable explant grown for 10 days in medium to which 50 /Ltg/ml of testosterone
propionate had been added. Note higher and winding epithelium, increased amount of
cytoplasm and secretory matter in the lumen. The connective tissue is much less dense as
compared with Fig. 13. Haematoxylin-eosin. x 120.
I L S E
L A S N I T Z K I
hormones, glands derived from 4-6-weeks-old mice underwent similar
changes to those found in castrated animals. In many alveoli the height
of the epithelium was reduced, the folding lost and the amount of
secretion diminished, while the stroma was increased, in both cells and
fibres, as compared with that seen in normal in vivo controls (Fig. 13).
FIG. 13. Explant of a prostate gland from a 6-week mouse grown for 10 days in medium
without added hormones. Note dilation of alveoli and low straight epithelium. Haematoxylin-eosin. x 120. (From Lasnitzki, 1951.)
FIG. 14. Comparable explant grown for 10 days in medium to which 50 /Ltg/ml of testosterone
propionate had been added. Note higher and winding epithelium, increased amount of
cytoplasm and secretory matter in the lumen. The connective tissue is much less dense as
compared with Fig. 13. Haematoxylin-eosin. x 120.