82
ORGANIC SYNTHESIS—1995
I.B.3-10 Shinokubo, H, Oshima, K., and Utimoto, K., TL, 35, 3741;
see also; Hodgson, D.M. et al., TL, 35, 2231.
OTBDMS
1 ·
RCH0
Br^f
2. *BuLi
Li
Br
3. I^CHO
O
R
R
1
4. HMPA
53-59%
I.B.3-11 Mitani, M. and Kobayashi, Y., BCJ, 67, 284; Hon, Y.-S. et
al., CC, 2041; Herrmann, W.A. et al., OM, 13, 4531.
TMSO
„,
TiClJLAH
R + CCI 4
►
R
Cl
10-75%
I.B.3-12 Rychnovsky, S.D. and Kim, J., JOC, 59, 2659.
R
R
Ph 3 P
Ph-OH
C0 2 Me
C0 2 Me
70-88%
I.B.3-13 Shimizu, I. et al., SL, 839.
R
1
R
3 X, Pd(OAc) 2 Kj
R
3 X, Pd(OAc) 2
R1
B114NCI, KOAc
MeCN, 80°C
TEA, dppb
NR
»►
DMF, 80°C
ORGANIC SYNTHESIS—1995
I.B.3-10 Shinokubo, H, Oshima, K., and Utimoto, K., TL, 35, 3741;
see also; Hodgson, D.M. et al., TL, 35, 2231.
OTBDMS
1 ·
RCH0
Br^f
2. *BuLi
Li
Br
3. I^CHO
O
R
R
1
4. HMPA
53-59%
I.B.3-11 Mitani, M. and Kobayashi, Y., BCJ, 67, 284; Hon, Y.-S. et
al., CC, 2041; Herrmann, W.A. et al., OM, 13, 4531.
TMSO
„,
TiClJLAH
R + CCI 4
►
R
Cl
10-75%
I.B.3-12 Rychnovsky, S.D. and Kim, J., JOC, 59, 2659.
R
R
Ph 3 P
Ph-OH
C0 2 Me
C0 2 Me
70-88%
I.B.3-13 Shimizu, I. et al., SL, 839.
R
1
R
3 X, Pd(OAc) 2 Kj
R
3 X, Pd(OAc) 2
R1
B114NCI, KOAc
MeCN, 80°C
TEA, dppb
NR
»►
DMF, 80°C