46
ORGANIC SYNTHESIS—1995
I.A.7.a.3-34 Marshall, J.A. et al., JOC, 59, 3413, 4122 & 3509.
Bn
OTBS
OBn
V
s
!
Bu 3 Sn
OMOM
BF 3 .OEt 2
0 H
OTBS
MOMO
OBn 72%
I.A.7.3.3-35 Keck, G.E. et al., TL, 35, 8323 & JOC, 59, 3113.
RCHO +
y
SnBu, (R)-BINOL
Ti(0'Pr) 4
R"
25-82%, 82-99% ee
I.A.7.a.3-36 Falck, J.R. et al., JACS, 116, 1; see also: Echavarren,
A.M. et al., JOC, 59, 4179.
OBz
^ " \
+ PhCOCl
CH 3 (CH 2 ) 6 ^ ^SnBu 3
Pd(PPh 3 ) 2 CI 2
CuCN, PhMe
75°C, 18h
CH 3 (CH 2 ) 6
74%
Ph
O
ORGANIC SYNTHESIS—1995
I.A.7.a.3-34 Marshall, J.A. et al., JOC, 59, 3413, 4122 & 3509.
Bn
OTBS
OBn
V
s
!
Bu 3 Sn
OMOM
BF 3 .OEt 2
0 H
OTBS
MOMO
OBn 72%
I.A.7.3.3-35 Keck, G.E. et al., TL, 35, 8323 & JOC, 59, 3113.
RCHO +
y
SnBu, (R)-BINOL
Ti(0'Pr) 4
R"
25-82%, 82-99% ee
I.A.7.a.3-36 Falck, J.R. et al., JACS, 116, 1; see also: Echavarren,
A.M. et al., JOC, 59, 4179.
OBz
^ " \
+ PhCOCl
CH 3 (CH 2 ) 6 ^ ^SnBu 3
Pd(PPh 3 ) 2 CI 2
CuCN, PhMe
75°C, 18h
CH 3 (CH 2 ) 6
74%
Ph
O