USEFUL SYNTHETIC PREPARATIONS
335
VI.A.2-7 Jenner, G. and Ben Taleb, A., JOM, 470, 257; Osakada, K., Sato,
R. and Yamamoto, T., OM, 13,4645.
Ar-ΓΙ
HCQ 2 Me,PdCl 2 (PCy 3 ) 2
A r
C l
R u 3 ( C O ) 1 2 , 1 6 0 ° C A r - C 0 2 H
15-66 %
VI.A.2-8 Yamakawa, K. et al., TL, 35, 133.
R
Ph
1: KH,*BuLi
2: aq KOH
CI
R
C0 2 H
70-95 %
VLA.2-9 Wasserman, H.H. and Ho, W.B., JOC, 59, 4364.
O
O
«
EDCI, DMAP
II
||
R
-
C O
*
H
CH ? Cl„rt ' A x C N Q 3 ,-78°C t R > \ -
O R
Ph 3 P^CN
L 3 ROH,CH 2 Cl 2
jl
59-80 %
58-89 %
VI.A.2-10 Nakamura, E. et al., JACS, 116, 1123.
- A
C0 2 Me
°~A
/
H 3 0
+
H0 2
^7
C0 2 Me
54%
335
VI.A.2-7 Jenner, G. and Ben Taleb, A., JOM, 470, 257; Osakada, K., Sato,
R. and Yamamoto, T., OM, 13,4645.
Ar-ΓΙ
HCQ 2 Me,PdCl 2 (PCy 3 ) 2
A r
C l
R u 3 ( C O ) 1 2 , 1 6 0 ° C A r - C 0 2 H
15-66 %
VI.A.2-8 Yamakawa, K. et al., TL, 35, 133.
R
Ph
1: KH,*BuLi
2: aq KOH
CI
R
C0 2 H
70-95 %
VLA.2-9 Wasserman, H.H. and Ho, W.B., JOC, 59, 4364.
O
O
«
EDCI, DMAP
II
||
R
-
C O
*
H
CH ? Cl„rt ' A x C N Q 3 ,-78°C t R > \ -
O R
Ph 3 P^CN
L 3 ROH,CH 2 Cl 2
jl
59-80 %
58-89 %
VI.A.2-10 Nakamura, E. et al., JACS, 116, 1123.
- A
C0 2 Me
°~A
/
H 3 0
+
H0 2
^7
C0 2 Me
54%