334
ORGANIC SYNTHESIS—1995
VI.A.2-3 Leiker, B.A. et al., TL, 35, 5205; Naso, F. et al., TI, 35,4635;
Griengl, H. et al., M, 125,469; Csuk, R. and Dorr, P., TA, 5, 269; SanchezMontero, J.M. et al., T, 50, 10749; Rakels, J.L.L. et al., TA, 5,93;
Kazlauskas, R.J. et al., JOC, 59, 2075.
R
R
^ R
f
LipasePS-30
I
f
J^
pH 7-7.4, H 2 0
1
+
*
HO
C0 2 Et
HO
C0 2 H
HO
C0 2 Et
51-66 %, 14-89 % e.e.
Vl.A.2-4 Turner, N.J. et al., JCS(Pl), 1679.
Regioselective Hydrolysis of Aromatic Dinitriles Using a Whole
Cell Catalyst
VI.A.2-5 Fisher, L.E. et al., CJC, 72, 142.
O
O
M
TiCl 4 , HCl, aq dioxane, A ^
II
R ^ ^ N H 2
R ^ X M l
78-92 %
VI.A.2-6 Anand, R.C. and Selvapalm, N., SC, 24, 2743; King, S.A., JOC,
59, 2253.
O
O
X
O
Amberlyst 15, MeOH, rt ^
r ^ O M e
"OH
94%