320
ORGANIC SYNTHESIS—1995
V.B. Amine Protecting Groups
V.B-1 Tsubouchi, H. et al., SL y 63.
R - N H 2
21-92 %
Primary ,
0 2 N,
/
V
\mine
o
XX>
m
'
c
O
\ θ 2 Ν
1: MeNHNH 2
DMF, rt
2: AcOH
Protecting Group
p
N - R
o
95-97 %
V.B-2 Periasamy, M., SC, 24, 313.
R'
I
R
Bn
PhNEt r BI 3 , CIC0 2 Et
R·
I
R
H
85-89 %
V.B-3 Wei, Z.Y. and Knaus, E.E., TL, 35, 847; Yoon, H. et al., TL, 35,
3745.
R - ^ χ , ^ Ο
MgiOMek, MeOH
N
I
C0 2 R·
R ^ X T ^ O
N
I
H
78-90 %
ORGANIC SYNTHESIS—1995
V.B. Amine Protecting Groups
V.B-1 Tsubouchi, H. et al., SL y 63.
R - N H 2
21-92 %
Primary ,
0 2 N,
/
V
\mine
o
XX>
m
'
c
O
\ θ 2 Ν
1: MeNHNH 2
DMF, rt
2: AcOH
Protecting Group
p
N - R
o
95-97 %
V.B-2 Periasamy, M., SC, 24, 313.
R'
I
R
Bn
PhNEt r BI 3 , CIC0 2 Et
R·
I
R
H
85-89 %
V.B-3 Wei, Z.Y. and Knaus, E.E., TL, 35, 847; Yoon, H. et al., TL, 35,
3745.
R - ^ χ , ^ Ο
MgiOMek, MeOH
N
I
C0 2 R·
R ^ X T ^ O
N
I
H
78-90 %