SYNTHESIS OF HETEROCYCLES
291
IV.K.3-5 Mitchell, M.A. and Benicewicz, B.C., S, 675.
J L ^ S L ^
C I
KF/AI 2 0 3
R—
31-93%
IV.K.3-6 Eastwood, F.W. et al., TL, 35, 2039.
2. Ni0 2
Pli
IV.K.3-7 Meyers, A.I. et al., TL, 35, 2481 and 2477.
o ^ R '
NBS,m) ^
P^f*'
~ ~ \ ^ ^
l
Bu0 2 C(0)Ph
~ ~ \ - A *
N
CO,R"
„ „ „ „
N
X O , R "
CuBr, Ph-H, 80 °C
similarly using Ni0 2
IV.K.3-8 Nitz, T.J. et al., JOC, 59, 5828; He, Y. and Lin, N.H., S, 989.
1. BuLi
2. RCON(OMe)Me
J|
3. H 2 S0 4 ,H 2 0
NOH
THF, Δ
38-94%
291
IV.K.3-5 Mitchell, M.A. and Benicewicz, B.C., S, 675.
J L ^ S L ^
C I
KF/AI 2 0 3
R—
31-93%
IV.K.3-6 Eastwood, F.W. et al., TL, 35, 2039.
2. Ni0 2
Pli
IV.K.3-7 Meyers, A.I. et al., TL, 35, 2481 and 2477.
o ^ R '
NBS,m) ^
P^f*'
~ ~ \ ^ ^
l
Bu0 2 C(0)Ph
~ ~ \ - A *
N
CO,R"
„ „ „ „
N
X O , R "
CuBr, Ph-H, 80 °C
similarly using Ni0 2
IV.K.3-8 Nitz, T.J. et al., JOC, 59, 5828; He, Y. and Lin, N.H., S, 989.
1. BuLi
2. RCON(OMe)Me
J|
3. H 2 S0 4 ,H 2 0
NOH
THF, Δ
38-94%