290
ORGANIC SYNTHESIS—1995
ÏV.K.3,
Heterocvcles with ΐ N and 1 O
IV.K.3-1 Doyle, K.J. and Moody, C.J., T, 50, 3761.
_ /
s °
2 P h
RMOAc) 4 .
/ ^ r
s °
2 P h
RCN + N ^
2
4
>
R-H(
I
C02Et
enea
V H > E t
22-71%
IV.K.3-2 Umezawa, J. et al., TA, 5, 491; Bulataova, O.F. et al., JOU,
30, 58.
R
'^A ^ £ ^ RA-A R )r\
k 2
acid
Νγ<>
«y
Me
Me
66-91%, 100:0 to 27:73
IV.K.3-3 Masuda, R. et al., H, 37, 153 and 38, 803.
Bu* N
_ \ - C F 3
I- Si0 2 (wet), 70°
N—/
M e
/ N
~
N
\
2
·
POC
'
3
'
Pyr
'
W
\Λ«*,
92-99%
IV.K.3-4 Natale, N.R. et al., SC, 24, 399.
,
^
^
^
s?
^ y \ ^Cl
aaEtOH
ORGANIC SYNTHESIS—1995
ÏV.K.3,
Heterocvcles with ΐ N and 1 O
IV.K.3-1 Doyle, K.J. and Moody, C.J., T, 50, 3761.
_ /
s °
2 P h
RMOAc) 4 .
/ ^ r
s °
2 P h
RCN + N ^
2
4
>
R-H(
I
C02Et
enea
V H > E t
22-71%
IV.K.3-2 Umezawa, J. et al., TA, 5, 491; Bulataova, O.F. et al., JOU,
30, 58.
R
'^A ^ £ ^ RA-A R )r\
k 2
acid
Νγ<>
«y
Me
Me
66-91%, 100:0 to 27:73
IV.K.3-3 Masuda, R. et al., H, 37, 153 and 38, 803.
Bu* N
_ \ - C F 3
I- Si0 2 (wet), 70°
N—/
M e
/ N
~
N
\
2
·
POC
'
3
'
Pyr
'
W
\Λ«*,
92-99%
IV.K.3-4 Natale, N.R. et al., SC, 24, 399.
,
^
^
^
s?
^ y \ ^Cl
aaEtOH