CARBON-CARBON BOND FORMING REACTIONS
I.A.5. Alkylations of Organometallic Reagents
(see also: I.B.3., I.B.4., I.F., I.G.)
15
I.A.5-1 Hunter, R. et al., T, 50, 871.
OMe
P l f ^ O M e
inter alia
LiBuB(allyl) 3
»
TMSOTf, THF
-78°C to 0°C
)Me
Ph*
94%
I.A.5-2 Soderberg, B.C., Nystrom, J.-E. et al., T, 50, 61.
R 2 1) LDA
2) Pd(dba) 2 , Ph 3 P
23-69%
I.A.5-3 Maiorana, S., Papagni, A. et al., TL, 35, 6377; see also: RoseMunch, F. et al., JOM, 476, C25.
Û
(OC) 5 C
1) LDA, -78°C
2) RX,-78 to 0°C (OC) 5 C
Me
30-80%
(OC) 5 C
CH 2 R
I.A.5. Alkylations of Organometallic Reagents
(see also: I.B.3., I.B.4., I.F., I.G.)
15
I.A.5-1 Hunter, R. et al., T, 50, 871.
OMe
P l f ^ O M e
inter alia
LiBuB(allyl) 3
»
TMSOTf, THF
-78°C to 0°C
)Me
Ph*
94%
I.A.5-2 Soderberg, B.C., Nystrom, J.-E. et al., T, 50, 61.
R 2 1) LDA
2) Pd(dba) 2 , Ph 3 P
23-69%
I.A.5-3 Maiorana, S., Papagni, A. et al., TL, 35, 6377; see also: RoseMunch, F. et al., JOM, 476, C25.
Û
(OC) 5 C
1) LDA, -78°C
2) RX,-78 to 0°C (OC) 5 C
Me
30-80%
(OC) 5 C
CH 2 R