CARBON-CARBON BOND FORMING REACTIONS
I.A.2-12 Leahy, J.W. et al., TL, 35, 7601.
Ψ
LDA
RCH 2 X
61-65%
product stereochemistry opposite to that expected
I.A.3. Alkylations of ß-Dicarbonyl. ß-Cyanocarbonyl Systems
and Other Active Methvlene Compounds
I.A.3-1 Iqbal, J. et al., T, 50, 9145.
OAc R
3
R IA S;: A R2
ΛΛ
CoCl 2
QT R
46-83%
I.A.3-2 Groth, U. et al., LA, 891, 665, 669; Nagasaka, T. et al., H, 39,
171.
O
1)KH
C0 2 Me
2) ZnCl 2
3) SPh
R^Cl
^
Î^Me
*
' PhS
35-90%
other Lewis acids, bases and leaving groups also used
I.A.2-12 Leahy, J.W. et al., TL, 35, 7601.
Ψ
LDA
RCH 2 X
61-65%
product stereochemistry opposite to that expected
I.A.3. Alkylations of ß-Dicarbonyl. ß-Cyanocarbonyl Systems
and Other Active Methvlene Compounds
I.A.3-1 Iqbal, J. et al., T, 50, 9145.
OAc R
3
R IA S;: A R2
ΛΛ
CoCl 2
QT R
46-83%
I.A.3-2 Groth, U. et al., LA, 891, 665, 669; Nagasaka, T. et al., H, 39,
171.
O
1)KH
C0 2 Me
2) ZnCl 2
3) SPh
R^Cl
^
Î^Me
*
' PhS
35-90%
other Lewis acids, bases and leaving groups also used