Table 10.1
(continued)
Associated compound or
diet type
Modulated genes
Function
Model
Reference
Anthocyanin-rich tart
cherries
PPAR-a
PPAR-c
IL-6
TNF-a
Nuclear hormone receptors
that control lipid
oxidation, adipocyte
differentiation, glucose
and lipid storage
Inflammation process
In vivo (rats)
Seymour et al. (2009)
Long-term dietary
restriction
Proglucagon;
Cholecystokinin;
Ghrelin;
GOAT;
Insulin secretagogue
Responsible for stimulating
the digestion of fat and
protein
Stimulates food intake and
promotes energy storage
In vivo (rats)
Reimer et al. (2010)
Propionic acid
Leptin:
Regulates adipose tissue
mass
In vivo (humans)
Al-Lahham et al. (2010)
Dietary mix [(resveratrol,
green tea extract, atocopherol, vitamin C,
n-3 (omega-3)
polyunsaturated fatty
acids, and tomato
extract]
Genes, transcriptome
adipose tissue (197
genes)
Overweight
In vivo (humans)
Bakker et al. (2010)
Coronary diseases
Whole grape
PPAR-a:
PPAR-c: Coactivator-1a:
PPAR-c:
Inhibitor-jBa:
Cardiac inflammation and
fibrosis
NF-jB inhibitor
In vivo (rats)
Seymour et al. (2010)
Soy protein
PPARa:
Protein-1;
Cardiac inflammation and
fibrosis
Sterol regulatory element
binding
In vivo (rats)
Torre-Villalvazo et al. (2009)
(continued)
302
R. Campos-Vega et al.