435
Higgs DM, Radford CA (2013) The contribution of the lateral line to ‘hearing’ in fi sh. J Exp Biol
216:1484–1490
Hirose Y, Simon JA, Ou HC (2011) Hair cell toxicity in anti-cancer drugs: evaluating an anticancer drug library for independent and synergistic toxic effects on hair cells using the zebrafish lateral line. J Assoc Res Otolaryngol. doi: 10.1007/s10162-011-0278-z
Jacques BE, Montgomery WH 4th, Uribe PM, Yatteau A, Asuncion JD, Resendiz G, Matsui JI,
Dabdoub A (2014) The role of Wnt/β-catenin signaling in proliferation and regeneration of the
developing basilar papilla and lateral line. Dev Neurobiol 74(4):438–456
Jiang H, Sha SH, Forge A, Schacht J (2006) Caspase-independent pathways of hair cell death
induced by kanamycin in vivo. Cell Death Differ 13(1):20–30
Jiang L, Romero-Carvajal A, Haug JS, Seidel CW, Piotrowski T (2014) Gene-expression analysis
of hair cell regeneration in the zebrafi sh lateral line. Proc Natl Acad Sci. doi: 10.1073/
pnas.1402898111
Kalmijn AJ (1988) Hydrodynamic and acoustic fi eld detection. In: Fay RR, Popper AN, Tavolga
WN (eds) Sensory biology of aquatic animals. Springer-Verlag, New York
Kaufman CK, White RM, Zon L (2009) Chemical genetic screening in the zebrafi sh embryo. Nat
Protoc 4(10):1422–1432
Kim K-J, Yoon K-Y, Lee B-Y (2012) Low molecular weight fucoidan from the sporophyll of
Undaria pinnatifi da suppresses infl ammation by promoting the inhibition of mitogen-activated
protein kinases and oxidative stress in RAW264.7 cells. Fitoterapia 83(8):1628–1635
Lanford PJ, Popper AN (1996) A unique afferent structure in the crista ampullaris of the goldfi sh.
J Comp Neurol 366:572–579
Lanford PJ, Platt C, Popper AN (2000) Structure and function in the saccule of the goldfi sh
( Carassius auratus ): a model of diversity in the non-amniote ear. Hear Res 143:1–13
Liang J, Wang D, Renaud G, Wolfberg TG, Wilson AF, Burgess SM (2012) The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafi sh. J Neurosci 32(31):10662–10673
Linbo TL, Stehr CM, Incardona JP, Scholz NL (2006) Dissolved copper triggers cell death in the
peripheral mechanosensory system of larval fi sh. Environ Toxicol Chem 25(2):597–603
Lombarte A, Yan HY, Popper AN, Chang JS, Platt C (1993) Damage and regeneration of hair cell
ciliary bundles in a fi sh ear following treatment with gentamicin. Hear Res 64(2):166–174
Lush ME, Piotrowski T (2014) Sensory hair cell regeneration in the zebrafi sh lateral line. Dev Dyn
243:1187–1202
Lynch ED, Gu R, Pierce C, Kil J (2005) Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen. Hear Res 201:81–89
Ma EY, Rubel EW, Raible DW (2008) Notch signaling regulates the extent of hair cell regeneration in the zebrafi sh lateral line. J Neurosci 28(9):2261–2273
Mackenzie SM, Raible DW (2012) Proliferative regeneration of zebrafi sh lateral line hair cells
after different ototoxic insults. PLoS One 7(10), e47257
Matsui JI, Ogilvie JM, Warchol ME (2002) Inhibition of caspases prevents ototoxic and ongoing
hair cell death. J Neurosci 22(4):1218–1227
Matsui JI, Gale JE, Warchol ME (2004) Critical signaling events during the aminoglycosideinduced death of sensory hair cells in vitro. J Neurobiol 61(2):250–266
Matsuura S, Ikeda K, Furukawa T (1971) Effects of streptomycin, kanamycin, quinine, and other
drugs on the microphonic potentials of goldfi sh sacculus. Jpn J Physiol 21:579–590
Mirjany M, Preuss T, Faber DS (2011) Role of the lateral line mechanosensory system in directionality of goldfi sh auditory escape response. J Exp Biol 214(20):3358–3367
Montgomery JC, Baker CF, Carton AG (1997) The lateral line can mediate rheotaxis in fi sh. Nature
389:960–963
Moon IS, So JH, Jung YM, Lee WS, Kim EY, Choi JH, Kim CH, Choi JY (2011) Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death.
Hear Res 282(1–2):236–242
Nakashima T, Teranishi M, Hibi T, Kobayashi M, Umemura M (2000) Vestibular and cochlea
toxicity of aminoglycosides. Acta Otolaryngol 120:904–911
Chemical Ototoxicity of the Fish Inner Ear and Lateral Line
Higgs DM, Radford CA (2013) The contribution of the lateral line to ‘hearing’ in fi sh. J Exp Biol
216:1484–1490
Hirose Y, Simon JA, Ou HC (2011) Hair cell toxicity in anti-cancer drugs: evaluating an anticancer drug library for independent and synergistic toxic effects on hair cells using the zebrafish lateral line. J Assoc Res Otolaryngol. doi: 10.1007/s10162-011-0278-z
Jacques BE, Montgomery WH 4th, Uribe PM, Yatteau A, Asuncion JD, Resendiz G, Matsui JI,
Dabdoub A (2014) The role of Wnt/β-catenin signaling in proliferation and regeneration of the
developing basilar papilla and lateral line. Dev Neurobiol 74(4):438–456
Jiang H, Sha SH, Forge A, Schacht J (2006) Caspase-independent pathways of hair cell death
induced by kanamycin in vivo. Cell Death Differ 13(1):20–30
Jiang L, Romero-Carvajal A, Haug JS, Seidel CW, Piotrowski T (2014) Gene-expression analysis
of hair cell regeneration in the zebrafi sh lateral line. Proc Natl Acad Sci. doi: 10.1073/
pnas.1402898111
Kalmijn AJ (1988) Hydrodynamic and acoustic fi eld detection. In: Fay RR, Popper AN, Tavolga
WN (eds) Sensory biology of aquatic animals. Springer-Verlag, New York
Kaufman CK, White RM, Zon L (2009) Chemical genetic screening in the zebrafi sh embryo. Nat
Protoc 4(10):1422–1432
Kim K-J, Yoon K-Y, Lee B-Y (2012) Low molecular weight fucoidan from the sporophyll of
Undaria pinnatifi da suppresses infl ammation by promoting the inhibition of mitogen-activated
protein kinases and oxidative stress in RAW264.7 cells. Fitoterapia 83(8):1628–1635
Lanford PJ, Popper AN (1996) A unique afferent structure in the crista ampullaris of the goldfi sh.
J Comp Neurol 366:572–579
Lanford PJ, Platt C, Popper AN (2000) Structure and function in the saccule of the goldfi sh
( Carassius auratus ): a model of diversity in the non-amniote ear. Hear Res 143:1–13
Liang J, Wang D, Renaud G, Wolfberg TG, Wilson AF, Burgess SM (2012) The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafi sh. J Neurosci 32(31):10662–10673
Linbo TL, Stehr CM, Incardona JP, Scholz NL (2006) Dissolved copper triggers cell death in the
peripheral mechanosensory system of larval fi sh. Environ Toxicol Chem 25(2):597–603
Lombarte A, Yan HY, Popper AN, Chang JS, Platt C (1993) Damage and regeneration of hair cell
ciliary bundles in a fi sh ear following treatment with gentamicin. Hear Res 64(2):166–174
Lush ME, Piotrowski T (2014) Sensory hair cell regeneration in the zebrafi sh lateral line. Dev Dyn
243:1187–1202
Lynch ED, Gu R, Pierce C, Kil J (2005) Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen. Hear Res 201:81–89
Ma EY, Rubel EW, Raible DW (2008) Notch signaling regulates the extent of hair cell regeneration in the zebrafi sh lateral line. J Neurosci 28(9):2261–2273
Mackenzie SM, Raible DW (2012) Proliferative regeneration of zebrafi sh lateral line hair cells
after different ototoxic insults. PLoS One 7(10), e47257
Matsui JI, Ogilvie JM, Warchol ME (2002) Inhibition of caspases prevents ototoxic and ongoing
hair cell death. J Neurosci 22(4):1218–1227
Matsui JI, Gale JE, Warchol ME (2004) Critical signaling events during the aminoglycosideinduced death of sensory hair cells in vitro. J Neurobiol 61(2):250–266
Matsuura S, Ikeda K, Furukawa T (1971) Effects of streptomycin, kanamycin, quinine, and other
drugs on the microphonic potentials of goldfi sh sacculus. Jpn J Physiol 21:579–590
Mirjany M, Preuss T, Faber DS (2011) Role of the lateral line mechanosensory system in directionality of goldfi sh auditory escape response. J Exp Biol 214(20):3358–3367
Montgomery JC, Baker CF, Carton AG (1997) The lateral line can mediate rheotaxis in fi sh. Nature
389:960–963
Moon IS, So JH, Jung YM, Lee WS, Kim EY, Choi JH, Kim CH, Choi JY (2011) Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death.
Hear Res 282(1–2):236–242
Nakashima T, Teranishi M, Hibi T, Kobayashi M, Umemura M (2000) Vestibular and cochlea
toxicity of aminoglycosides. Acta Otolaryngol 120:904–911
Chemical Ototoxicity of the Fish Inner Ear and Lateral Line