DBD-FISH 282,283,284,285,286,287,
288, 289
Decondensation solution 127
Decondensed chromatin 22
Degenerate oligonucleotide primer 388
- DOP-PCR 13, 185, 198,201 388
- DOP-primer 389
Dehydration 316,319
Deletions 197
Denaturation 100, 118, 130, 132.395,412
Denaturation and hybridization 103
Denaturation step 15
Denaturing time 420
Deparaffmization 152
Derivatization of glass substrates 233,
245
Detection of numerical aberrations 445
Detection scheme 341,416
Developmental delay 402
Dewaxing 10
Dextran sulfate 319
(d) H 2 0 331
Diagnostic threshold 458
Dichroic mirror 56
Dideoxy-PRINS 463,464,465,469
Differentiation state 443
Diffraction 51
DiGeorge syndrome 30
Digital image analysis 286, 287, 288
Digital images 403
Digital imaging 211
Digitizer 55
Digoxigenin 13, 351, 296
Directly labeled probes 447
Directly labeled nucleotides 396
Discriminate among closely related
sequences 463
Discriminate single base variation 466
Discriminating on the basis of single base
difference 463
Dissection needle 393
Dithioerythritol 127
Dithiothreitol 331
DNA breaks 282,284,285,287,288,289
DNA chips 473
DNA copy number 197
DNA fiber mapping 226
DNA fibers 226,227,228, 236, 237, 241,
243,245,246,249
DNA libraries 294
DNA methylation 279
Dot blot test 314
Double hybridization reaction 355
Doubling time 266
Drosophila melanogaster 323
Dynamic range 55, 61
E
Ebstein Barr virus 155
Effective contrast 53
Embedding medium 143
ERBB2 481
Ethidium bromide 391
Eukitt 142
Exonuclease III (ExoIII) 275
Exonuclease III 266
Expanded trinucleotide repeats 466
Expression profiling 474
Extended focus image 62
F
False color 406
False negative signals 135
False positive signals 135
False-positive results 117
fetal organs 155
Fiber-FISH 22,221
Fibroblast controls 144
FICTION 39, 442
- Fluorescence, immunophenotyping
and interphase cytogenetics 39
Filter sets 456
Fluorescence in situ hybridization
(FISH) 398, 408
- FISH 262, 301
- CO-FISH 262
- COD-FISH 264
- High Resolution FISH 221
Fixation step 9
Fixative 100, 128
Fluorescein 257,351
Fluorescein-12 - UTP 417
Fluorescence filters 56, 57
Fluorescence Immunophenotyping and
Interphase Cytogenetics as Tool for
Investigation of Neoplasms 442
Fluorescence intensity ratios 406
Fluorescent dyes 257
Subject Index
489
288, 289
Decondensation solution 127
Decondensed chromatin 22
Degenerate oligonucleotide primer 388
- DOP-PCR 13, 185, 198,201 388
- DOP-primer 389
Dehydration 316,319
Deletions 197
Denaturation 100, 118, 130, 132.395,412
Denaturation and hybridization 103
Denaturation step 15
Denaturing time 420
Deparaffmization 152
Derivatization of glass substrates 233,
245
Detection of numerical aberrations 445
Detection scheme 341,416
Developmental delay 402
Dewaxing 10
Dextran sulfate 319
(d) H 2 0 331
Diagnostic threshold 458
Dichroic mirror 56
Dideoxy-PRINS 463,464,465,469
Differentiation state 443
Diffraction 51
DiGeorge syndrome 30
Digital image analysis 286, 287, 288
Digital images 403
Digital imaging 211
Digitizer 55
Digoxigenin 13, 351, 296
Directly labeled probes 447
Directly labeled nucleotides 396
Discriminate among closely related
sequences 463
Discriminate single base variation 466
Discriminating on the basis of single base
difference 463
Dissection needle 393
Dithioerythritol 127
Dithiothreitol 331
DNA breaks 282,284,285,287,288,289
DNA chips 473
DNA copy number 197
DNA fiber mapping 226
DNA fibers 226,227,228, 236, 237, 241,
243,245,246,249
DNA libraries 294
DNA methylation 279
Dot blot test 314
Double hybridization reaction 355
Doubling time 266
Drosophila melanogaster 323
Dynamic range 55, 61
E
Ebstein Barr virus 155
Effective contrast 53
Embedding medium 143
ERBB2 481
Ethidium bromide 391
Eukitt 142
Exonuclease III (ExoIII) 275
Exonuclease III 266
Expanded trinucleotide repeats 466
Expression profiling 474
Extended focus image 62
F
False color 406
False negative signals 135
False positive signals 135
False-positive results 117
fetal organs 155
Fiber-FISH 22,221
Fibroblast controls 144
FICTION 39, 442
- Fluorescence, immunophenotyping
and interphase cytogenetics 39
Filter sets 456
Fluorescence in situ hybridization
(FISH) 398, 408
- FISH 262, 301
- CO-FISH 262
- COD-FISH 264
- High Resolution FISH 221
Fixation step 9
Fixative 100, 128
Fluorescein 257,351
Fluorescein-12 - UTP 417
Fluorescence filters 56, 57
Fluorescence Immunophenotyping and
Interphase Cytogenetics as Tool for
Investigation of Neoplasms 442
Fluorescence intensity ratios 406
Fluorescent dyes 257
Subject Index
489