32 Centromere-Specific Multicolor-FISH (cenM-FISH)
427
Fig. l. cenM-FISH result of a prenatal case: the supernumerary marker chromosome (arrowhead) was determined as derived from chromosome 8. No specific signals could be observed using 24-color-FISH with whole chromosome painting probes (result not shown).
Image was captured on a Zeiss Axioplan microscope using the isis digital FISH imaging
system (MetaSystems, Altlussheim, Germany) using an XC77 CCD camera with on-chip
integration (Sony); karyogram was created using the ikaros karyotyping system (MetaSysterns, Altlussheim, Germany), B Labeling scheme of the centromere-specific probes used for
cenM-FISH
427
Fig. l. cenM-FISH result of a prenatal case: the supernumerary marker chromosome (arrowhead) was determined as derived from chromosome 8. No specific signals could be observed using 24-color-FISH with whole chromosome painting probes (result not shown).
Image was captured on a Zeiss Axioplan microscope using the isis digital FISH imaging
system (MetaSystems, Altlussheim, Germany) using an XC77 CCD camera with on-chip
integration (Sony); karyogram was created using the ikaros karyotyping system (MetaSysterns, Altlussheim, Germany), B Labeling scheme of the centromere-specific probes used for
cenM-FISH