19 PNA-FISH
261
References
Chen C, Hong Y-Ket al. (1999). Single Base discrimination ofcen P-B repeats on mouse
and human chromosomes with PNA-FISH. Mammalian Genome 10:13-18
Chen C, Wu B et aI. (2000). Chromosome identification and sequence-specific structural analysis with short DNA oligomers. Mammalian Genome 11:384-391
Egholm, M , O. Buchardt et al. (1993). PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick Hydrogen bonding rules. Nature 365: 566-568
Egholm, M., O. Buchardt, et al. (1992). Peptide nucleic acids (PNA): Oligonucleotide
analogues with an achiral peptide backbone. J. Am. Chern. Soc. 114: 1895-1897
Hande, M. P., P. M. Lansdorp, et al. (1998). Induction of telomerase activity by in vivo
X-irradiation of mouse splenocytes and its possible role in chromosome healing.
Mutant Res 404(1-2): 205-14
Hultdin, M., E. Gunlund, et al. (1998). Telomere analysis by fluorescence in situ hybridization and flow cytometry. Nucleic Acids Res 26(16): 3651-6
Lansdorp, P. M., N. P. Verwoerd, et al. (1996). Heterogeneity in telomere length of
human chromosomes. Human Mol. Gen. 5(5): 685-691
Lawrence JB, Singer RH, McNeil JA (1990) Interphase and metaphase resolution of
different distances within the human dystrophin gene. Science 249, 928-932
Leijon, M., A. Graslund, et al. (1994). Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation. Biochemistry 33:
9820-9825
Martens, U. M., J.Mark, et al. (1998). Short telomeres on human chromosome 17p.
Nature Genetics: 76-80
Nielsen, P. E., M. Egholm, et al. (1991). Sequence-selective recognition of DNA by
strand displacement with a thymine-substituted polyamide. Science 254: 1497-1500
Nielsen, P. E., M. Egholm, et al. (1993). Peptide nucleic acids (PNAs): Potential Antisense and Anti-gene Agents. Anti-Cancer Drug Design 8: 53-63
Rufer, N., W. Dragowska, et al. (1998). Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nature Biotechnology 16: 743-747
Taneja, K. 1. (1998). Localization of trinucleotide repeat sequences in myotonic dystrophy cells using a single fluorochrome-labeled PNA probe. BioTechniques 24(3):
472-476
Abbreviations
DAPI
FISH
PBS
PI
PNA
Q-FISH
TFA
of 4,6-diamidino-2-phenylindole-dehydrochloride
fluorescence in situ hybridization
phosphate-buffered saline
propidium iodide
peptide nucleic acid
quantitative FISH
trifluoroacetic acid
261
References
Chen C, Hong Y-Ket al. (1999). Single Base discrimination ofcen P-B repeats on mouse
and human chromosomes with PNA-FISH. Mammalian Genome 10:13-18
Chen C, Wu B et aI. (2000). Chromosome identification and sequence-specific structural analysis with short DNA oligomers. Mammalian Genome 11:384-391
Egholm, M , O. Buchardt et al. (1993). PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick Hydrogen bonding rules. Nature 365: 566-568
Egholm, M., O. Buchardt, et al. (1992). Peptide nucleic acids (PNA): Oligonucleotide
analogues with an achiral peptide backbone. J. Am. Chern. Soc. 114: 1895-1897
Hande, M. P., P. M. Lansdorp, et al. (1998). Induction of telomerase activity by in vivo
X-irradiation of mouse splenocytes and its possible role in chromosome healing.
Mutant Res 404(1-2): 205-14
Hultdin, M., E. Gunlund, et al. (1998). Telomere analysis by fluorescence in situ hybridization and flow cytometry. Nucleic Acids Res 26(16): 3651-6
Lansdorp, P. M., N. P. Verwoerd, et al. (1996). Heterogeneity in telomere length of
human chromosomes. Human Mol. Gen. 5(5): 685-691
Lawrence JB, Singer RH, McNeil JA (1990) Interphase and metaphase resolution of
different distances within the human dystrophin gene. Science 249, 928-932
Leijon, M., A. Graslund, et al. (1994). Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation. Biochemistry 33:
9820-9825
Martens, U. M., J.Mark, et al. (1998). Short telomeres on human chromosome 17p.
Nature Genetics: 76-80
Nielsen, P. E., M. Egholm, et al. (1991). Sequence-selective recognition of DNA by
strand displacement with a thymine-substituted polyamide. Science 254: 1497-1500
Nielsen, P. E., M. Egholm, et al. (1993). Peptide nucleic acids (PNAs): Potential Antisense and Anti-gene Agents. Anti-Cancer Drug Design 8: 53-63
Rufer, N., W. Dragowska, et al. (1998). Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nature Biotechnology 16: 743-747
Taneja, K. 1. (1998). Localization of trinucleotide repeat sequences in myotonic dystrophy cells using a single fluorochrome-labeled PNA probe. BioTechniques 24(3):
472-476
Abbreviations
DAPI
FISH
PBS
PI
PNA
Q-FISH
TFA
of 4,6-diamidino-2-phenylindole-dehydrochloride
fluorescence in situ hybridization
phosphate-buffered saline
propidium iodide
peptide nucleic acid
quantitative FISH
trifluoroacetic acid