21 Histopathological Alterations of the Mantle of Mytilus galloprovincialis. . .
247
Acknowledgment The authors thank Antonio Antepazos and the fishermen of the “Antepazos
I”, who kindly provided the mussels used in this work. Furthermore, we would like to thank
to the Spanish Institute of Oceanography from Vigo (IEO), contracted for the determination
of contaminants. This work was supported by a grant from Autonomous Galician Government
(PGIDT10MDS312030PR).
References
Aarab N, Minier C, Lemaire S, Unruh E, Hansen PD, Larsen BK, Andersen OK, Narbonne JF
(2004) Biochemical and histological responses in mussel (Mytilus edulis) exposed to North
Sea oil and to a mixture of North Sea oil and alkylphenols. Mar Environ Res 58:437–441
Alonso A, Su´ arez P, ´
Alvarez C, San Juan F, Molist P (2001) Structural study of a possible neoplasia
detected in Mytilus galloprovincialis collected from the Ria of Vigo (NW Spain). Dis Aquat
Organ 47:73–79
Au DWT, Yurchenko OV, Reunov AA (2003) Sublethal effects of phenol on spermatogenesis in
sea urchins (Anthocidaris crassispina). Environ Res 93:92–98
Barber BJ (2004) Neoplastic diseases of commercially important marine bivalves. Aquat Living
Resour 17:449–466
Bert TM, Hesselman DM, Arnold WS, Moore WS, Cruz-L´ opez H, Marelli DC (1993) High
frequency of gonadal neoplasia in hard clam (Mercenaria spp.) hybrid zone. Mar Biol
117:97–104
Besada V, Fumega J, Vaamonde A (2002) Temporal trends of Cd, Cu, Hg, Pb and Zn in
mussel (Mytilus galloprovincialis) from the Spanish North-Atlantic coast 1991–1999. Sci Total
Environ 288(3):239–253
Carella F, Restucci B, Maiolino P, De Vico G (2009) A case of germinoma in a limpet (Patella
coerulea) (Patellogastropoda). J Invertebr Pathol 101:154–156
Cheng TC (1984) A classification of molluscan hemocytes based on functional evidences. In:
Cheng TC (ed) Comparative pathobiology, invertebrate blood cells and serum factors, vol 6.
Plenum, New York, pp 111–146
Clarke KR, Gorley RN (2006) PRIMER (Plymouth Routines in Multivariate Ecological Research)
v6: user manual/tutorial. PRIMER-E Ltd, Plymouth Marine Laboratory, Plymouth
Darriba S, Iglesias D, Harshbarger JC, L´ opez C (2006) Germinoma in razor clam Ensis arcuatus
(Jeffreys, 1865) in Galicia (NW Spain). J Invertebr Pathol 93:140–142
De Boer J (1988) Chlorobiphenyls in bound and non-bound lipid of fishes, comparison of different
extraction methods. Chemosphere 17(9):1811–1819
Elston RA, Moore JD, Brooks K (1992) Disseminated neoplasia of bivalve molluscs. Rev Aquat
Sci 6:405–466
Facchinelli A, Sacchi E, Mallen L (2001) Multivariate statistical and GIS-based approach to
identify heavy metal source in soils. Environ Pollut 114:313–324
Ford SE, Barber RD, Marks E (1997) Disseminated neoplasia in juvenile eastern oyster Crassostrea virginica, and its relationship to the reproductive cycle. Dis Aquat Organ 28:73–77
Gardner GR, Yevich PP, Hurst P, Theyer P, Benyi S, Harshbarger JC, Pruell RJ (1991) Germinomas
and teratoid siphon anomalies in softshell clams, Mya arenaria, environmentally exposed to
herbicides. J Environ Health Perspect 90:43–51
Gonz´ alez-Quijano A, Fumega J (1996) Determinaci´ on de cong´ eneres individuales de bifenilos
policlorados en organismos marinos. Bolet´ ın del Instituto Espa˜ nol de Oceanograf´ ıa 160:27pp
Hauptmann S, Budianto D, Denkert C, Kobel M, Borsi L, Siri A (2003) Adhesion and migration
of HRT-18 coloreetal carcinoma cells on extracellular matrix components typical for the
desmoplastic stroma of colorectal adenocarcinomas. Oncology 65(2):174–181
Hesselman DM, Blake NJ, Peters EC (1988) Gonadal neoplasms in hard shell clams Mercenaria
spp., from the Indian River lagoon Florida: occurrence, prevalence and histopathology.
J Invertebr Pathol 52:436–446
247
Acknowledgment The authors thank Antonio Antepazos and the fishermen of the “Antepazos
I”, who kindly provided the mussels used in this work. Furthermore, we would like to thank
to the Spanish Institute of Oceanography from Vigo (IEO), contracted for the determination
of contaminants. This work was supported by a grant from Autonomous Galician Government
(PGIDT10MDS312030PR).
References
Aarab N, Minier C, Lemaire S, Unruh E, Hansen PD, Larsen BK, Andersen OK, Narbonne JF
(2004) Biochemical and histological responses in mussel (Mytilus edulis) exposed to North
Sea oil and to a mixture of North Sea oil and alkylphenols. Mar Environ Res 58:437–441
Alonso A, Su´ arez P, ´
Alvarez C, San Juan F, Molist P (2001) Structural study of a possible neoplasia
detected in Mytilus galloprovincialis collected from the Ria of Vigo (NW Spain). Dis Aquat
Organ 47:73–79
Au DWT, Yurchenko OV, Reunov AA (2003) Sublethal effects of phenol on spermatogenesis in
sea urchins (Anthocidaris crassispina). Environ Res 93:92–98
Barber BJ (2004) Neoplastic diseases of commercially important marine bivalves. Aquat Living
Resour 17:449–466
Bert TM, Hesselman DM, Arnold WS, Moore WS, Cruz-L´ opez H, Marelli DC (1993) High
frequency of gonadal neoplasia in hard clam (Mercenaria spp.) hybrid zone. Mar Biol
117:97–104
Besada V, Fumega J, Vaamonde A (2002) Temporal trends of Cd, Cu, Hg, Pb and Zn in
mussel (Mytilus galloprovincialis) from the Spanish North-Atlantic coast 1991–1999. Sci Total
Environ 288(3):239–253
Carella F, Restucci B, Maiolino P, De Vico G (2009) A case of germinoma in a limpet (Patella
coerulea) (Patellogastropoda). J Invertebr Pathol 101:154–156
Cheng TC (1984) A classification of molluscan hemocytes based on functional evidences. In:
Cheng TC (ed) Comparative pathobiology, invertebrate blood cells and serum factors, vol 6.
Plenum, New York, pp 111–146
Clarke KR, Gorley RN (2006) PRIMER (Plymouth Routines in Multivariate Ecological Research)
v6: user manual/tutorial. PRIMER-E Ltd, Plymouth Marine Laboratory, Plymouth
Darriba S, Iglesias D, Harshbarger JC, L´ opez C (2006) Germinoma in razor clam Ensis arcuatus
(Jeffreys, 1865) in Galicia (NW Spain). J Invertebr Pathol 93:140–142
De Boer J (1988) Chlorobiphenyls in bound and non-bound lipid of fishes, comparison of different
extraction methods. Chemosphere 17(9):1811–1819
Elston RA, Moore JD, Brooks K (1992) Disseminated neoplasia of bivalve molluscs. Rev Aquat
Sci 6:405–466
Facchinelli A, Sacchi E, Mallen L (2001) Multivariate statistical and GIS-based approach to
identify heavy metal source in soils. Environ Pollut 114:313–324
Ford SE, Barber RD, Marks E (1997) Disseminated neoplasia in juvenile eastern oyster Crassostrea virginica, and its relationship to the reproductive cycle. Dis Aquat Organ 28:73–77
Gardner GR, Yevich PP, Hurst P, Theyer P, Benyi S, Harshbarger JC, Pruell RJ (1991) Germinomas
and teratoid siphon anomalies in softshell clams, Mya arenaria, environmentally exposed to
herbicides. J Environ Health Perspect 90:43–51
Gonz´ alez-Quijano A, Fumega J (1996) Determinaci´ on de cong´ eneres individuales de bifenilos
policlorados en organismos marinos. Bolet´ ın del Instituto Espa˜ nol de Oceanograf´ ıa 160:27pp
Hauptmann S, Budianto D, Denkert C, Kobel M, Borsi L, Siri A (2003) Adhesion and migration
of HRT-18 coloreetal carcinoma cells on extracellular matrix components typical for the
desmoplastic stroma of colorectal adenocarcinomas. Oncology 65(2):174–181
Hesselman DM, Blake NJ, Peters EC (1988) Gonadal neoplasms in hard shell clams Mercenaria
spp., from the Indian River lagoon Florida: occurrence, prevalence and histopathology.
J Invertebr Pathol 52:436–446