118
C. Picot et al.
Table 10.3
Acute dietary intakes of domoic acid, okadaic acid and spirolide obtained by a probabilistic approach and comparison
with toxicological reference values for each bivalve species
DA
OA
SPX
Exposure* (g/kg
bw/portion)
Exposure* (ng/kg
bw/portion)
Exposure* (ng/kg
bw/portion)
Mean Median
P95
Mean
Median
P95
Mean Median P95
Harvested oysters
0.16
0.06
0.65
19:4
7.62
78:1 8:60
5:46
27:4
Harvested mussels
0.52
0.20
2.09
456
151
1;912
26:0
13:3
94:8
Harvested cockles
0.70
0.27
2.75
702
243
2;808
78:4
49:6
250
Harvested carpet shell clams
0.74
0.29
3.02
378
149
1;466
19:8
12:3
60:00
Harvested razor clams
0.14
0.05
0.53
133
44.9
569
8:58
5:50
27:2
Purchased oysters
0.15
0.06
0.61
17:7
7.1
72
8:10
5:21
25:5
Purchased mussels
0.61
0.24
2.41
183
79
706
29:9
15:6
105
Purchased cockles
0.02
0.01
0.07
4:00 1.7
18
1:90
1:20
6:00
Purchased carpet shell clams 0.03
0.01
0.13
3:80 1.5
15
0:7
0:45
2:20
Purchased razor clams
0
0
0
0
0
0
0
0
0
ARfD
100
a
/30
b
333
a
/300
b
No ARfD allocated
ARfD
acute reference dose
*Assuming a body weight equals to 60 kg
a
JECFA
Joint FAO/WHO Expert Committee on Food Additives
b
EFSA
European Food Safety Authority