~
T able
2.1
Partial Pharm acolog ical Profile of Some N euroh ypophy sial Ho rmones (Uf mg )
0'
Fro g bladder
Hormone
Rat
Rat uterus
Mammary gland
Water
Sodium
antidiuretic
oxy toc ic
milk let dow n
tr ansf er
tr ansport
with
without
Mg
2+
Mg
2+
Arg 8
-
va sopre ssin (AD H )
400
20
34
70
26
33
Lys" -
vas opressin (ADH - Pigs)
250
5
60
5
5
Arg 8
-
oxytocin (Vasotocin)
186
139
264
100
10000
1100
Ox ytocin
5
450
450
450
450
450
Ile" - oxyto cin (mesotocin)
1
289
375
328
-
507
Ser! -
Ile" - oxytocin (ichthyotocin, isotocin).
1
150
420
300
-
5
Other assay pr eparations include frog and toad skin, toad bladd er, hen and turtle oviduct,
decrease in blood pr essure of chicken, increase in blood pr essure of rat, antidi uresis in
frogs and chickens. From :
MOREL an d J ARD
(1968); FITZPATRICK and BENTLEY
(1968)