284
Table 5.3
Vaccines for A. salmonicida
A. salmonicida
strain used for
vaccine and/or
challenge
Nature of
vaccine
Method of
administration
Nature of
challenge
Type of
fi sh used
Water
temp. (°C)
Ability of
vaccine to
protect fi sh
Ability of vaccine
to induce antibody
response
Reference
Whole cell
virulent
Chloroform
inactivated
Oral
Immersion/i.p./
co-habitation
Cutthroat trout
(1–2 years)
19
+
+ (Average 1:80) Duff ( 1942 )
NG
Heat inactivated Oral
i.p.
Brook trout
−
−
−
Snieszko and
Friddle ( 1949 )
NG
Heat inactivated Oral
Natural
As above
−
+
−
As above
Ex-brook trout
(vaccine)
Formalised
i.p.
i.p.
Brook and brown
trout (0 to 2+ years)
11
−
+ (1:160)
Krantz et al.
( 1964b )
Ex-brook trout
(vaccine)
Formalised +
adjuvant
i.p.
i.p.
As above
11
+
+ (1:10520)
Krantz et al.
( 1964b )
ATCC 14174 + 6
strains from
hatcheries
Formalised
Oral
Water-borne
Coho salmon
(0 to 1+ years)
13
−
−
Spence et al.
( 1965 )
As above
Formalised +
FCA
i.p.
NG
Rainbow trout
(2 to 4+ years)
12
ND
+ (1:5120)
Spence et al.
( 1965 )
AS 67
Formalised +
FCA
i.p.
ND
Coho salmon
(1+ years)
13
ND
+ (1:20480)
Cisar and Fryer
( 1974 )
Ex-salmon
Formalised +
FCA
i.p.
i.p.
Coho salmon
(juveniles)
12
+
+ (1:40960)
Paterson and
Fryer ( 1974a )
SS-70 (virulent) Formalised
Oral
Natural
Coho salmon
(juveniles)
NG
−
−
Udey and Fryer
(
1978 )
SS-70 (virulent) Formalised +
Al(OH) 3
Oral
Natural
Coho salmon
(juveniles)
NG
−
−
Udey and Fryer
( 1978 )
S-70 (virulent)
Formalised +
FCA
i.p.
Natural
Coho salmon
(juveniles)
NG
+
+ (NG)
Udey and Fryer
( 1978 )
36/75
Formalised
Oral
i.m.
Rainbow trout
15
−
−
Michel (
1979 )
5 Aeromonadaceae Representative (Aeromonas salmonicida)