Part A | 5
62 Part A Marine Flora and Fauna
oil-producing alga Nannochloropsis sp., Proc. Natl.
Acad. Sci. USA 108, 21265–21269 (2011)
5.69 J. Elhai: Genetic techniques appropriate for the
biotechnological exploitation of cyanobacteria,
J. Appl. Phycol. 6, 177–186 (1994)
5.70 R.C. Murphy, S.E. Stevens: Cloning and expression
of the cryIVD gene of Bacillus thuringiensis subsp
israelensis in the cyanobacterium Agmenellum quadruplicatum Pr-6 and its resulting larvicidal activity,
Appl. Environ. Microbiol. 58, 1650–1655 (1992)
5.71 H. Takeyama, D. Takeda, K. Yazawa, A. Yamada,
T. Matsunaga: Expression of the eicosapentaenoic
acid synthesis gene cluster from Shewanella sp., in
a transgenic marine cyanobacterium, Synechococcus
sp., Microbiology 143, 2725–2731 (1997)
5.72 J.S. Buzby, R.D. Porter, S.E. Stevens: Plasmid transformation in Agmenellum quadruplicatum Pr-6 –
construction of biphasic plasmids and characterization of their transformation properties, J. Bacteriol.
154, 1446–1450 (1983)
5.73 H. Takeyama, H. Nakayama, T. Matsunaga: Salinityregulated replication of the endogenous plasmid
pSY10 from the marine cyanobacterium Synechococcus sp., Appl. Biochem. Biotechnol. 84–6, 447–453
(2000)
5.74 K. Sode, M. Tatara, H. Takeyama, J.G. Burgess,
T. Matsunaga: Conjugative gene-transfer in marine
cyanobacteria – Synechococcus sp., Synechocystis sp.
and Pseudanabaena sp., Appl. Microbiol. Biotechnol. 37, 369–373 (1992)
5.75 K. Sode, M. Tatara, S. Ogawa, T. Matsunaga: Maintenance of broad host range vector pKT230 in marine
unicellular cyanobacteria, FEMS Microbiol. Lett. 99,
73–78 (1992)
5.76 R.S. Safferman, M.E. Morris: Algal virus: Isolation,
Science 140, 679–680 (1963)
5.77 K. Sode, M. Oozeki, K. Asakawa, J. Burgess, T. Matsunaga: Isolation of a marine cyanophage infecting
the marine unicellular cyanobacterium, Synechococcus sp. NKBG 042902, J. Mar. Biotechnol. 1, 189–192
(1994)
5.78 O. Bergh, K.Y. Borsheim, G. Bratbak, M. Heldal: High
abundance of viruses found in aquatic environments, Nature 340, 467–468 (1989)
5.79 Y. Zhong, F. Chen, S.W. Wilhelm, L. Poorvin, R.E. Hodson: Phylogenetic diversity of marine cyanophage
isolates and natural virus communities as revealed
by sequences of viral capsid assembly protein
gene G20, Appl. Environ. Microbiol. 68, 1576–1584
(2002)
5.80 A. Hallmann: Algal transgenics and biotechnology,
Transgenic Plant J. 1, 8 (2007)
5.81 D. Armaleo, G.N. Ye, T.M. Klein, K.B. Shark, J.C. Sanford, S.A. Johnston: Biolistic nuclear transformation
of Saccharomyces cerevisiae and other fungi, Curr.
Genet. 17, 97–103 (1990)
5.82 L.E. Brown, S.L. Sprecher, L.R. Keller: Introduction of
exogenous DNA into Chlamydomonas reinhardtii by
electroporation, Mol. Cell. Biol. 11, 2328–2332 (1991)
5.83 J.M. Coll: Methodologies for transferring DNA into
eukaryotic microalgae, Span. J. Agric. Res. 4, 316–330
(2006)
5.84 B. Zorin, Y. Lu, I. Sizova, P. Hegemann: Nuclear
gene targeting in Chlamydomonas as exemplified
by disruption of the PHOT gene, Gene 432, 91–96
(2009)
5.85 A. Hallmann, A. Rappel, M. Sumper: Gene replacement by homologous recombination in the multicellular green alga Volvox carteri, Proc. Natl. Acad. Sci.
USA 94, 7469–7474 (1997)
5.86 R. Yu, A. Yamada, K. Watanabe, K. Yazawa,
H. Takeyama, T. Matsunaga, R. Kurane: Production
of eicosapentaenoic acid by a recombinant marine
cyanobacterium Synechococcus sp., Lipids 35, 1061–
1064 (2000)
5.87 M. Harker, J. Hirschberg: Biosynthesis of ketocarotenoids in transgenic cyanobacteria expressing
the algal gene for ˇ-C-4-oxygenase, crtO, FEBS Lett.
404, 129–134 (1997)
5.88 K. Takahama, M. Matsuoka, K. Nagahama, T. Ogawa:
Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted
gene for an ethylene-forming enzyme at the PsbAI
locus, J. Biosci. Bioeng. 95, 302–305 (2003)
5.89 A. Hallmann, M. Sumper: The chlorella hexose/HC
symporter is a useful selectable marker and biochemical reagent when expressed in Volvox, Proc.
Natl. Acad. Sci. USA 93, 669–673 (1996)
5.90 A. Doebbe, J. Rupprecht, J. Beckmann, J.H. Mussgnug, A. Hallmann, B. Hankamer, O. Kruse: Functional integration of the HUP1 hexose symporter
gene into the genome of C. reinhardtii: Impacts on
biological H 2 production, J. Biotechnol. 131, 27–33
(2007)
5.91 L.A. Zaslavskaia, J.C. Lippmeier, C. Shih, D. Ehrhardt,
A.R. Grossman, K.E. Apt: Trophic obligate conversion
of an photoautotrophic organism through metabolic
engineering, Science 292, 2073–2075 (2001)
5.92 A. Melis: Solar energy conversion efficiencies in
photosynthesis: Minimizing the chlorophyll antennae to maximize efficiency, Plant Sci. 177, 272–280
(2009)
5.93 R. Radakovits, P.M. Eduafo, M.C. Posewitz: Genetic
engineering of fatty acid chain length in Phaeodactylum tricornutum, Metab. Eng. 13, 89–95 (2011)
5.94 A.S. Miron, A.C. Gomez, F.G. Camacho, E.M. Grima,
Y. Chisti: Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae, J. Biotechnol. 70, 249–270 (1999)
5.95 G. Vunjak-Novakovic, Y. Kim, X.X. Wu, I. Berzin,
J.C. Merchuk: Air-lift bioreactors for algal growth
on flue gas: Mathematical modeling and pilotplant studies, Ind. Eng. Chem. Res. 44, 6154–6163
(2005)
5.96 J. Degen, A. Uebele, A. Retze, U. Schmid-Staiger,
W. Trosch: A novel airlift photobioreactor with baffles
for improved light utilization through the flashing
light effect, J. Biotechnol. 92, 89–94 (2001)
62 Part A Marine Flora and Fauna
oil-producing alga Nannochloropsis sp., Proc. Natl.
Acad. Sci. USA 108, 21265–21269 (2011)
5.69 J. Elhai: Genetic techniques appropriate for the
biotechnological exploitation of cyanobacteria,
J. Appl. Phycol. 6, 177–186 (1994)
5.70 R.C. Murphy, S.E. Stevens: Cloning and expression
of the cryIVD gene of Bacillus thuringiensis subsp
israelensis in the cyanobacterium Agmenellum quadruplicatum Pr-6 and its resulting larvicidal activity,
Appl. Environ. Microbiol. 58, 1650–1655 (1992)
5.71 H. Takeyama, D. Takeda, K. Yazawa, A. Yamada,
T. Matsunaga: Expression of the eicosapentaenoic
acid synthesis gene cluster from Shewanella sp., in
a transgenic marine cyanobacterium, Synechococcus
sp., Microbiology 143, 2725–2731 (1997)
5.72 J.S. Buzby, R.D. Porter, S.E. Stevens: Plasmid transformation in Agmenellum quadruplicatum Pr-6 –
construction of biphasic plasmids and characterization of their transformation properties, J. Bacteriol.
154, 1446–1450 (1983)
5.73 H. Takeyama, H. Nakayama, T. Matsunaga: Salinityregulated replication of the endogenous plasmid
pSY10 from the marine cyanobacterium Synechococcus sp., Appl. Biochem. Biotechnol. 84–6, 447–453
(2000)
5.74 K. Sode, M. Tatara, H. Takeyama, J.G. Burgess,
T. Matsunaga: Conjugative gene-transfer in marine
cyanobacteria – Synechococcus sp., Synechocystis sp.
and Pseudanabaena sp., Appl. Microbiol. Biotechnol. 37, 369–373 (1992)
5.75 K. Sode, M. Tatara, S. Ogawa, T. Matsunaga: Maintenance of broad host range vector pKT230 in marine
unicellular cyanobacteria, FEMS Microbiol. Lett. 99,
73–78 (1992)
5.76 R.S. Safferman, M.E. Morris: Algal virus: Isolation,
Science 140, 679–680 (1963)
5.77 K. Sode, M. Oozeki, K. Asakawa, J. Burgess, T. Matsunaga: Isolation of a marine cyanophage infecting
the marine unicellular cyanobacterium, Synechococcus sp. NKBG 042902, J. Mar. Biotechnol. 1, 189–192
(1994)
5.78 O. Bergh, K.Y. Borsheim, G. Bratbak, M. Heldal: High
abundance of viruses found in aquatic environments, Nature 340, 467–468 (1989)
5.79 Y. Zhong, F. Chen, S.W. Wilhelm, L. Poorvin, R.E. Hodson: Phylogenetic diversity of marine cyanophage
isolates and natural virus communities as revealed
by sequences of viral capsid assembly protein
gene G20, Appl. Environ. Microbiol. 68, 1576–1584
(2002)
5.80 A. Hallmann: Algal transgenics and biotechnology,
Transgenic Plant J. 1, 8 (2007)
5.81 D. Armaleo, G.N. Ye, T.M. Klein, K.B. Shark, J.C. Sanford, S.A. Johnston: Biolistic nuclear transformation
of Saccharomyces cerevisiae and other fungi, Curr.
Genet. 17, 97–103 (1990)
5.82 L.E. Brown, S.L. Sprecher, L.R. Keller: Introduction of
exogenous DNA into Chlamydomonas reinhardtii by
electroporation, Mol. Cell. Biol. 11, 2328–2332 (1991)
5.83 J.M. Coll: Methodologies for transferring DNA into
eukaryotic microalgae, Span. J. Agric. Res. 4, 316–330
(2006)
5.84 B. Zorin, Y. Lu, I. Sizova, P. Hegemann: Nuclear
gene targeting in Chlamydomonas as exemplified
by disruption of the PHOT gene, Gene 432, 91–96
(2009)
5.85 A. Hallmann, A. Rappel, M. Sumper: Gene replacement by homologous recombination in the multicellular green alga Volvox carteri, Proc. Natl. Acad. Sci.
USA 94, 7469–7474 (1997)
5.86 R. Yu, A. Yamada, K. Watanabe, K. Yazawa,
H. Takeyama, T. Matsunaga, R. Kurane: Production
of eicosapentaenoic acid by a recombinant marine
cyanobacterium Synechococcus sp., Lipids 35, 1061–
1064 (2000)
5.87 M. Harker, J. Hirschberg: Biosynthesis of ketocarotenoids in transgenic cyanobacteria expressing
the algal gene for ˇ-C-4-oxygenase, crtO, FEBS Lett.
404, 129–134 (1997)
5.88 K. Takahama, M. Matsuoka, K. Nagahama, T. Ogawa:
Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted
gene for an ethylene-forming enzyme at the PsbAI
locus, J. Biosci. Bioeng. 95, 302–305 (2003)
5.89 A. Hallmann, M. Sumper: The chlorella hexose/HC
symporter is a useful selectable marker and biochemical reagent when expressed in Volvox, Proc.
Natl. Acad. Sci. USA 93, 669–673 (1996)
5.90 A. Doebbe, J. Rupprecht, J. Beckmann, J.H. Mussgnug, A. Hallmann, B. Hankamer, O. Kruse: Functional integration of the HUP1 hexose symporter
gene into the genome of C. reinhardtii: Impacts on
biological H 2 production, J. Biotechnol. 131, 27–33
(2007)
5.91 L.A. Zaslavskaia, J.C. Lippmeier, C. Shih, D. Ehrhardt,
A.R. Grossman, K.E. Apt: Trophic obligate conversion
of an photoautotrophic organism through metabolic
engineering, Science 292, 2073–2075 (2001)
5.92 A. Melis: Solar energy conversion efficiencies in
photosynthesis: Minimizing the chlorophyll antennae to maximize efficiency, Plant Sci. 177, 272–280
(2009)
5.93 R. Radakovits, P.M. Eduafo, M.C. Posewitz: Genetic
engineering of fatty acid chain length in Phaeodactylum tricornutum, Metab. Eng. 13, 89–95 (2011)
5.94 A.S. Miron, A.C. Gomez, F.G. Camacho, E.M. Grima,
Y. Chisti: Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae, J. Biotechnol. 70, 249–270 (1999)
5.95 G. Vunjak-Novakovic, Y. Kim, X.X. Wu, I. Berzin,
J.C. Merchuk: Air-lift bioreactors for algal growth
on flue gas: Mathematical modeling and pilotplant studies, Ind. Eng. Chem. Res. 44, 6154–6163
(2005)
5.96 J. Degen, A. Uebele, A. Retze, U. Schmid-Staiger,
W. Trosch: A novel airlift photobioreactor with baffles
for improved light utilization through the flashing
light effect, J. Biotechnol. 92, 89–94 (2001)