273
Hagen C, Braune W, Greulich F (1993) Functional aspects of secondary carotenoids in
Haematococcus lacustris [Girod] Rostafinski (Volvocales) IV. Protection from photodynamic
damage. J Photochem Photobiol B Biol 20:153–160
Halliwell B, Gutteridge J (1999) Free radicals in biology and medicine, 3rd edn. Oxford University
Press, New York
Hardison RC, Alexandersson M, Cawley S et al (2003) Comparative genomics. PLoS Biol 1:e58
He Q, Yang H, Wu L, Hu C (2015) Effect of light intensity on physiological changes, carbon allocation and neutral lipid accumulation in oleaginous microalgae. Bioresour Technol 191:219–228
Hong ME, Hwang SK, Chang WS et al (2015) Enhanced autotrophic astaxanthin production from
Haematococcus pluvialis under high temperature via heat stress-driven Haber–Weiss reaction.
Appl Microbiol Biotechnol 99:5203–5215
Hong SJ, Lee CG (2015) Microalgal systems biology for biofuel production. In: Algal Biorefineries.
Springer International Publishing, Cham, pp 3–21
Hu CW, Chuang LT, Yu PC, Chen CNN (2013) Pigment production by a new thermotolerant
microalga Coelastrella sp. F50. Food Chem 138:2071–2078
Hu Z, Li Y, Sommerfeld M et al (2008) Enhanced protection against oxidative stress in an
astaxanthin- overproduction Haematococcus mutant (Chlorophyceae). Eur J Phycol 43:365–376
Ip PF, Chen F (2005) Employment of reactive oxygen species to enhance astaxanthin formation in
Chlorella zofingiensis in heterotrophic culture. Process Biochem 40:3491–3496
Jamers A, Blust R, De Coen W (2009) Omics in algae: paving the way for a systems biological
understanding of algal stress phenomena? Aquat Toxicol 92:114–121
Jamers A, Van der Ven K, Moens L et al (2006) Effect of copper exposure on gene expression profiles in Chlamydomonas reinhardtii based on microarray analysis. Aquat Toxicol 80:249–260
John RP, Anisha GS, Nampoothiri KM (2011) Micro and macroalgal biomass: a renewable source
for bioethanol. Bioresour Technol 102:186–193
Kobayashi M (2000) In vivo antioxidant role of astaxanthin under oxidative stress in the green alga
Haematococcus pluvialis. Appl Microbiol Biotechnol 54:550–555
Kobayashi M, Kakizono T, Nagai S (1993) Enhanced carotenoid biosynthesis by oxidative stress in
acetate-induced cyst cells of a green unicellular alga, Haematococcus pluvialis. Appl Environ
Microbiol 59:867–873
Kobayashi M, Kakizono T, Nishio N et al (1997a) Antioxidant role of astaxanthin in the green alga
Haematococcus pluvialis. Appl Microbiol Biotechnol 48:351–356
Kobayashi M, Kurimura Y, Kakizono T et al (1997b) Morphological changes in the life cycle of the
green alga Haematococcus pluvialis. J Ferment Bioeng 84:94–97
Kobayashi M, Sakamoto Y (1999) Singlet oxygen quenching ability of astaxanthin esters from the
green alga Haematococcus pluvialis. Biotechnol Lett 21:265–269
Krinsky NI (1979) Carotenoid protection against oxidation. Pure Appl Chem 51:649–660
Kullik I, Storz G (1994) Transcriptional regulators of the oxidative stress response in prokaryotes
and eukaryotes. Redox Rep 1:23–29
Kumar M, Gupta V, Trivedi N et al (2011a) Desiccation induced oxidative stress and its biochemical responses in intertidal red alga Gracilaria corticata (Gracilariales, Rhodophyta). Environ
Exp Bot 72:194–201
Kumar M, Gupta V, Kumari P et al (2011b) Assessment of nutrient composition and antioxidant
potential of Caulerpaceae seaweeds. J Food Compos Anal 24:270–278
Kumar M, Kuzhiumparambil U, Pernice M et al (2016) Metabolomics: an emerging frontier of
systems biology in marine macrophytes. Algal Res 16:76–92
Lee DY, Park J-J, Barupal DK, Fiehn O (2012) System response of metabolic networks in
Chlamydomonas reinhardtii to total available ammonium. Mol Cell Proteomics 11:973–988
Lemoine Y, Schoefs B (2010) Secondary ketocarotenoid astaxanthin biosynthesis in algae: a multifunctional response to stress. Photosynth Res 106:155–177
Li Y, Han D, Sommerfeld M, Hu Q (2011) Photosynthetic carbon partitioning and lipid production
in the oleaginous microalga Pseudochlorococcum sp. (Chlorophyceae) under nitrogen-limited
conditions. Bioresour Technol 102:123–129
13 Oxidative Stress-Induced Bioprospecting of Microalgae
Hagen C, Braune W, Greulich F (1993) Functional aspects of secondary carotenoids in
Haematococcus lacustris [Girod] Rostafinski (Volvocales) IV. Protection from photodynamic
damage. J Photochem Photobiol B Biol 20:153–160
Halliwell B, Gutteridge J (1999) Free radicals in biology and medicine, 3rd edn. Oxford University
Press, New York
Hardison RC, Alexandersson M, Cawley S et al (2003) Comparative genomics. PLoS Biol 1:e58
He Q, Yang H, Wu L, Hu C (2015) Effect of light intensity on physiological changes, carbon allocation and neutral lipid accumulation in oleaginous microalgae. Bioresour Technol 191:219–228
Hong ME, Hwang SK, Chang WS et al (2015) Enhanced autotrophic astaxanthin production from
Haematococcus pluvialis under high temperature via heat stress-driven Haber–Weiss reaction.
Appl Microbiol Biotechnol 99:5203–5215
Hong SJ, Lee CG (2015) Microalgal systems biology for biofuel production. In: Algal Biorefineries.
Springer International Publishing, Cham, pp 3–21
Hu CW, Chuang LT, Yu PC, Chen CNN (2013) Pigment production by a new thermotolerant
microalga Coelastrella sp. F50. Food Chem 138:2071–2078
Hu Z, Li Y, Sommerfeld M et al (2008) Enhanced protection against oxidative stress in an
astaxanthin- overproduction Haematococcus mutant (Chlorophyceae). Eur J Phycol 43:365–376
Ip PF, Chen F (2005) Employment of reactive oxygen species to enhance astaxanthin formation in
Chlorella zofingiensis in heterotrophic culture. Process Biochem 40:3491–3496
Jamers A, Blust R, De Coen W (2009) Omics in algae: paving the way for a systems biological
understanding of algal stress phenomena? Aquat Toxicol 92:114–121
Jamers A, Van der Ven K, Moens L et al (2006) Effect of copper exposure on gene expression profiles in Chlamydomonas reinhardtii based on microarray analysis. Aquat Toxicol 80:249–260
John RP, Anisha GS, Nampoothiri KM (2011) Micro and macroalgal biomass: a renewable source
for bioethanol. Bioresour Technol 102:186–193
Kobayashi M (2000) In vivo antioxidant role of astaxanthin under oxidative stress in the green alga
Haematococcus pluvialis. Appl Microbiol Biotechnol 54:550–555
Kobayashi M, Kakizono T, Nagai S (1993) Enhanced carotenoid biosynthesis by oxidative stress in
acetate-induced cyst cells of a green unicellular alga, Haematococcus pluvialis. Appl Environ
Microbiol 59:867–873
Kobayashi M, Kakizono T, Nishio N et al (1997a) Antioxidant role of astaxanthin in the green alga
Haematococcus pluvialis. Appl Microbiol Biotechnol 48:351–356
Kobayashi M, Kurimura Y, Kakizono T et al (1997b) Morphological changes in the life cycle of the
green alga Haematococcus pluvialis. J Ferment Bioeng 84:94–97
Kobayashi M, Sakamoto Y (1999) Singlet oxygen quenching ability of astaxanthin esters from the
green alga Haematococcus pluvialis. Biotechnol Lett 21:265–269
Krinsky NI (1979) Carotenoid protection against oxidation. Pure Appl Chem 51:649–660
Kullik I, Storz G (1994) Transcriptional regulators of the oxidative stress response in prokaryotes
and eukaryotes. Redox Rep 1:23–29
Kumar M, Gupta V, Trivedi N et al (2011a) Desiccation induced oxidative stress and its biochemical responses in intertidal red alga Gracilaria corticata (Gracilariales, Rhodophyta). Environ
Exp Bot 72:194–201
Kumar M, Gupta V, Kumari P et al (2011b) Assessment of nutrient composition and antioxidant
potential of Caulerpaceae seaweeds. J Food Compos Anal 24:270–278
Kumar M, Kuzhiumparambil U, Pernice M et al (2016) Metabolomics: an emerging frontier of
systems biology in marine macrophytes. Algal Res 16:76–92
Lee DY, Park J-J, Barupal DK, Fiehn O (2012) System response of metabolic networks in
Chlamydomonas reinhardtii to total available ammonium. Mol Cell Proteomics 11:973–988
Lemoine Y, Schoefs B (2010) Secondary ketocarotenoid astaxanthin biosynthesis in algae: a multifunctional response to stress. Photosynth Res 106:155–177
Li Y, Han D, Sommerfeld M, Hu Q (2011) Photosynthetic carbon partitioning and lipid production
in the oleaginous microalga Pseudochlorococcum sp. (Chlorophyceae) under nitrogen-limited
conditions. Bioresour Technol 102:123–129
13 Oxidative Stress-Induced Bioprospecting of Microalgae