186
c. Niehrs et al.
Kishimoto Y, Lee KH, Zon L, Hammerschmidt M, Schulte MS (1997) The
molecular nature of zebrafish swirl: BMP2 function is essential during early
dorsoventral patterning. Development 124:4457-66
Knecht A, Harland RM (1997) Mechanisms of dorsal-ventral patterning in
noggin-induced neural tissue. Development 124:2477-2488
Koster M, Plessow S, Clement JH, Lorenz A, Tiedemann H, Knochel W
(1991) Bone morphogenetic protein 4 (BMP-4), a member of the TGF-beta
family, in early embryos of Xenopus laevis: analysis of mesoderm inducing
activity. Mech Dev 33:191-9
Ladher R, Mohun TJ, Smith JC, Snape AM (1996) Xom: a Xenopus homeobox
gene that mediates the early effects of BMP-4. Development 122:2385-2394
Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM (1993) Neural induction by the secreted
polypeptide noggin. Science 262:713-8
Lecuit T, Brook WJ, Ng M, Calleja M, Sun H, Cohen S (1996) Two distinct
mechanisms for long-range patterning by decapentaplegic in the Drosophila
wing. Nature 381:387-392
Lemaire P (1996) The coming of age of ventralising homeobox genes in amphibian development. Bioessays 18:701-704
Liu F, Pouponnot C, Massague J (1997) Dual role of the Smad4IDPC4 tumor
suppressor in TGFbeta-inducible transcriptional complexes. Genes Dev
11:3157-67
Maeno M, Ong RC, Suzuki A, Ueno N, Kung HF (1994) A truncated bone
morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral
mesoderm. Proc Nat! Acad Sci USA 91:10260-4
Marchant L, Linker C, Ruiz P, Guerrero N, Mayor R (1998) The inductive
properties of mesoderm suggest that the neural crest cells are specified by a
BMP gradient. Dev BioI 15:319-329
Marques G, Musacchio M, Shimmel MJ, Wtinnenburg-Stapleton K, Cho
KWY, O'Connor MB (1997) Production of a dpp activity gradient in the
early Drosophila embryo through the opposing actions of SOG and TLD
proteins. Cell 91:417-426
Massague J, Hata A, Liu F (1997) TGF-beta signalling through the Smad pathway. Trends Cell BioI7:187-192
Meersman G, Verschueren K, Nelles L, Blumenstock C, Kraft H, Wuytens G,
Remade J, Kozak CA, Tylzanowsky P, Niehrs C, Huylebroeck D (1997) The
C-terminal domain of Mad-like signal transducers is sufficient for biological
activity in vivo and transcriptional activation. Mech Dev 61:127-140
Moos MJ, Wang S, Krinks M (1995) Anti-dorsalizing morphogenetic protein is
a novel TGF-beta homolog expressed in the Spemann organizer. Development 121:4293-301
c. Niehrs et al.
Kishimoto Y, Lee KH, Zon L, Hammerschmidt M, Schulte MS (1997) The
molecular nature of zebrafish swirl: BMP2 function is essential during early
dorsoventral patterning. Development 124:4457-66
Knecht A, Harland RM (1997) Mechanisms of dorsal-ventral patterning in
noggin-induced neural tissue. Development 124:2477-2488
Koster M, Plessow S, Clement JH, Lorenz A, Tiedemann H, Knochel W
(1991) Bone morphogenetic protein 4 (BMP-4), a member of the TGF-beta
family, in early embryos of Xenopus laevis: analysis of mesoderm inducing
activity. Mech Dev 33:191-9
Ladher R, Mohun TJ, Smith JC, Snape AM (1996) Xom: a Xenopus homeobox
gene that mediates the early effects of BMP-4. Development 122:2385-2394
Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM (1993) Neural induction by the secreted
polypeptide noggin. Science 262:713-8
Lecuit T, Brook WJ, Ng M, Calleja M, Sun H, Cohen S (1996) Two distinct
mechanisms for long-range patterning by decapentaplegic in the Drosophila
wing. Nature 381:387-392
Lemaire P (1996) The coming of age of ventralising homeobox genes in amphibian development. Bioessays 18:701-704
Liu F, Pouponnot C, Massague J (1997) Dual role of the Smad4IDPC4 tumor
suppressor in TGFbeta-inducible transcriptional complexes. Genes Dev
11:3157-67
Maeno M, Ong RC, Suzuki A, Ueno N, Kung HF (1994) A truncated bone
morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral
mesoderm. Proc Nat! Acad Sci USA 91:10260-4
Marchant L, Linker C, Ruiz P, Guerrero N, Mayor R (1998) The inductive
properties of mesoderm suggest that the neural crest cells are specified by a
BMP gradient. Dev BioI 15:319-329
Marques G, Musacchio M, Shimmel MJ, Wtinnenburg-Stapleton K, Cho
KWY, O'Connor MB (1997) Production of a dpp activity gradient in the
early Drosophila embryo through the opposing actions of SOG and TLD
proteins. Cell 91:417-426
Massague J, Hata A, Liu F (1997) TGF-beta signalling through the Smad pathway. Trends Cell BioI7:187-192
Meersman G, Verschueren K, Nelles L, Blumenstock C, Kraft H, Wuytens G,
Remade J, Kozak CA, Tylzanowsky P, Niehrs C, Huylebroeck D (1997) The
C-terminal domain of Mad-like signal transducers is sufficient for biological
activity in vivo and transcriptional activation. Mech Dev 61:127-140
Moos MJ, Wang S, Krinks M (1995) Anti-dorsalizing morphogenetic protein is
a novel TGF-beta homolog expressed in the Spemann organizer. Development 121:4293-301