162
U. Drescher
Acknowledgements. This work was supported in part by a biotechnology network grant from the European Union and grants from the Deutsche Forschungsgemeinschaft to UD.
References
Adams RH, Wilkinson GA, Weiss C, Die11a F, Gale NW, Deutsch U, Risau W,
Klein R (1999) Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis and sprouting angiogenesis. Genes Dev 13:295-306
Braisted JE, McLaughlin T, Wang HU, Friedman GC, Anderson DJ, O'Leary
DDM (1997) Graded and lamina-specific distributions of ligands of EphB
receptor tyrosine kinases in the developing retinotectal system. Dev BioI
191:14-28
Brambilla R, Bruckner K, Orioli D, Bergemann AD, Flanagan JG, Klein R
(1996) Similarities and differences in the way transmembrane-type ligands
interact with the elk subclass of Eph receptors. Mol Cell Neurosci
8:199-209
Brennan C, Monschau B, Lindberg R, Guthrie B, Drescher U, Bonhoeffer F,
Holder N (1997) Two Eph receptor tyrosine kinase ligands control axon
growth and may be involved in the creation of the retinotectal map in the
zebrafish. Development 124:655-664
Castellani V, Yue Y, Gao P-P, Zhou R, Bolz J (1998) Dual action of a ligand for
Eph receptor tyrosine kinases on specific populations ofaxons during the
development of cortical circuits. J Neurosci 18:4663-4672
Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG (1995) Complementary
gradients in expression and binding of elf-l and mek4 in development of
the topographic retinotectal projection map. Cell 82:371-381
Connor RJ, Menzel P, Pasquale EB (1998) Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the
visual system. Dev Bioi 193:21-35
Drescher U, Bonhoeffer F, MUller BK (1997) The Eph family in retinal axon
guidance. CUff Opin Neurobiol 7:75-80
Flanagan JG, Leder P (1990) The kit ligand: a cell surface molecule altered in
steel mutant fibroblasts. Cell 63: 185-194
Flanagan JG, Vanderhaeghen P (1998) The ephrins and Eph receptors in neural
development. Annu Rev Neurosci 21:309-45
Frisen J, Yates PA, McLaughlin T, Friedman GC, O'Leary DDM, Barbacid M
(1998) Ephrin-A5 (AL-lIRAGS) is essential for proper retinal axon guid-
U. Drescher
Acknowledgements. This work was supported in part by a biotechnology network grant from the European Union and grants from the Deutsche Forschungsgemeinschaft to UD.
References
Adams RH, Wilkinson GA, Weiss C, Die11a F, Gale NW, Deutsch U, Risau W,
Klein R (1999) Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis and sprouting angiogenesis. Genes Dev 13:295-306
Braisted JE, McLaughlin T, Wang HU, Friedman GC, Anderson DJ, O'Leary
DDM (1997) Graded and lamina-specific distributions of ligands of EphB
receptor tyrosine kinases in the developing retinotectal system. Dev BioI
191:14-28
Brambilla R, Bruckner K, Orioli D, Bergemann AD, Flanagan JG, Klein R
(1996) Similarities and differences in the way transmembrane-type ligands
interact with the elk subclass of Eph receptors. Mol Cell Neurosci
8:199-209
Brennan C, Monschau B, Lindberg R, Guthrie B, Drescher U, Bonhoeffer F,
Holder N (1997) Two Eph receptor tyrosine kinase ligands control axon
growth and may be involved in the creation of the retinotectal map in the
zebrafish. Development 124:655-664
Castellani V, Yue Y, Gao P-P, Zhou R, Bolz J (1998) Dual action of a ligand for
Eph receptor tyrosine kinases on specific populations ofaxons during the
development of cortical circuits. J Neurosci 18:4663-4672
Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG (1995) Complementary
gradients in expression and binding of elf-l and mek4 in development of
the topographic retinotectal projection map. Cell 82:371-381
Connor RJ, Menzel P, Pasquale EB (1998) Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the
visual system. Dev Bioi 193:21-35
Drescher U, Bonhoeffer F, MUller BK (1997) The Eph family in retinal axon
guidance. CUff Opin Neurobiol 7:75-80
Flanagan JG, Leder P (1990) The kit ligand: a cell surface molecule altered in
steel mutant fibroblasts. Cell 63: 185-194
Flanagan JG, Vanderhaeghen P (1998) The ephrins and Eph receptors in neural
development. Annu Rev Neurosci 21:309-45
Frisen J, Yates PA, McLaughlin T, Friedman GC, O'Leary DDM, Barbacid M
(1998) Ephrin-A5 (AL-lIRAGS) is essential for proper retinal axon guid-