312
Penicillium digitatum but the strong hemolytic activity offers obstacles in the path
of commercial development. Besides being strong antifungal agents amphipathic
syringomycins are strong biosurfactants. Lipodepsipeptides are another class of
modified lipopeptides produced by Pseudomonas spp. Syringopeptins are lipodepsipeptides containing either 22 or 25 amino acid residues attached at the N-terminus
to 3-hydroxy-decanoic acid or 3-hyroxydodecanoic acid depending on the strain
H 3 C
H 3 C
CH 3
CH 3
H 2 N
HO
OH
MUPIROCIN
PYOLUTEORIN
SYRINGOMYCIN
TABTOXIN
PYRROLNITRIN
OH
HO
OH
O
HN
CI
CI
OH
OH
OH
CH 3
CH 3
OH
OH
OH
OH
OH
CI
CI
CI
O
O
N
N
H
H
H
H
H
H
H
N
H
H
H
H
H
HN
NH
HN
NH 2
HN
HN
NH
NH 2
NH 2
NH 2
N
N
N
N
O
a
c
d
e
b
O
O O
O
O
HO
H
H
H
H
H
N
H
H
H
O
O
O
O
O
O
O
O
O
O
O
O
O
O
+
−
Fig. 12.7 Some antimicrobials produced by the genus Pseudomonas
D. Francis