194
Ammon HP, Safayhi H, Mack T, Sabieraj J (1993) Mechanism of antiinflammatory actions of
curcumine and boswellic acids. J Ethnopharmacol 38:113–119
Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB (2002) Curcumin (diferuloylmethane)
induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its
suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis 23:143–150
Bachmeier BE, Mohrenz IV, Mirisola V, Schleicher E, Romeo F, Hohneke C, Jochum M, Nerlich
AG, Pfeffer U (2008) Curcumin downregulates the inflammatory cytokines CXCL1 and −2 in
breast cancer cells via NFkappaB. Carcinogenesis 29(4):779–789
Bachmeier BE, Mirisola V, Romeo F, Generoso L, Esposito A, Dell’eva R, Blengio F, Killian PH,
Albini A, Pfeffer U (2010) Reference profile correlation reveals estrogen-like trancriptional
activity of curcumin. Cell Physiol Biochem 26(3):471–482
Balachandran P, Govindarajan R (2005) Cancer- ayurvedic perscpective. Pharmacol Res
51:19–30
Benhar M, Engelberg D, Levitski A (2002) ROS, stress activated kinases and stress signaling in
cancer. EMBO Rep 3:420–425
Berenblum I (1982) Sequential aspects of chemical carcinogenesis skin. In: Becker FF (ed) Cancer:
a comprehesive treatise, vol 1, 2nd edn. Plenum Publ. Corp, New York
Charaka (700 BC) Charaka Samhita. Chaukhamba Orientalia, Varanasi
Cho BJ, Im EK, Kwon JH, Lee KH, Shin HJ, Oh J, Kang SM, Chung JH, Jang Y (2005) Berberine
inhibits the production of lysophosphatidylcholine-induced reactive oxygen species and the
ERK1/2 pathway in vascular smooth muscle cells. Mol Cell 20:429–434
Craig WJ (1997) Phytochemicals: guardians of our health. J Am Diet Assoc 97:S199–S204
Craig WJ (1999) Health-promoting properties of common herbs. Am J Clin Nutr 70:491S–499S
Devi PU (1996) Withania somnifera Dunal (Ashwagandha): potential plant source of a promising
drug for cancer chemotherapy and radiosensitization. Indian J Exp Biol 34:927–932
Dorman HJ, Kosar M, Kahlos K, Holm Y, Hiltunen R (2003) Antioxidant properties and composition of aqueous extracts from Mentha species, hybrids, varieties and cultivars. J Agric Food
Chem 51:4563–4569
Dreosti IE (1996) Bioactive ingredients: antioxidants and polyphenols in tea. Nutr Rev
54:S51–S58
Du Q, Hu B, An HM, Shen KP, Xu L, Deng S, Wei MM (2013) Synergistic anticancer effects of
curcumin and RESV in Hepa1-6 hepatocellular carcinoma. Oncol Rep 29:1851–1858
El-Zayat AAE, Degen D, Drabek S, Clark GM, Pettit GR, Von Hoff DD (1993) In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum
Caffrum (arid shrub). Anti-Cancer Drugs 4:19–25
Gaidhani SN, Singh A, Kumari S, Lavekar GS, Juvekar AS, Sen S, Padhi MM (2013) Evaluation
of some plant extracts for standardization and anticancer activity. Indian J Tradit Knowl
12:682–687
Garodia P, Ichikawa H, Malani N, Sethi G, Aggarwal BB (2007) From ancient medicine to modern
medicine: ayurvedic concepts of health and their role in inflammation and cancer. J Soc Integr
Oncol 5(1 Winter):25–37
Glaser T, Winter S, Groscurth P, Safayhi H, Sailer ER, Ammon HP, Schabet M, Weller M (1999)
Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 80:756–765
Greenwell M, Rahman PKSM (2015) Medicinal plants: their use in anticancer treatment. Int
J Pharm Sci Res 6:4103–4112
Guyton KZ, Liu Y, Gorospe M, Xu Q, Holbrook NJ (1996) Activation of mitogen-activated protein
kinase by H2O2: role in cell survival following oxidant injury. J Biol Chem 271:4138–4142
Hamel E, Lin CM (1983) Interactions of combretastatin: a new plantderived antimitotic agent,
with tubulin. Biochem Pharmacol 32:3864–3867
Hansen JM, Go YM, Jones DP (2006) Nuclear and mitochondrial compartmentation of oxidative
stress and redox signaling. Annu Rev Pharmacol Toxicol 46:215–234
A. Augustine and G.S. Pillai
Ammon HP, Safayhi H, Mack T, Sabieraj J (1993) Mechanism of antiinflammatory actions of
curcumine and boswellic acids. J Ethnopharmacol 38:113–119
Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB (2002) Curcumin (diferuloylmethane)
induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its
suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis 23:143–150
Bachmeier BE, Mohrenz IV, Mirisola V, Schleicher E, Romeo F, Hohneke C, Jochum M, Nerlich
AG, Pfeffer U (2008) Curcumin downregulates the inflammatory cytokines CXCL1 and −2 in
breast cancer cells via NFkappaB. Carcinogenesis 29(4):779–789
Bachmeier BE, Mirisola V, Romeo F, Generoso L, Esposito A, Dell’eva R, Blengio F, Killian PH,
Albini A, Pfeffer U (2010) Reference profile correlation reveals estrogen-like trancriptional
activity of curcumin. Cell Physiol Biochem 26(3):471–482
Balachandran P, Govindarajan R (2005) Cancer- ayurvedic perscpective. Pharmacol Res
51:19–30
Benhar M, Engelberg D, Levitski A (2002) ROS, stress activated kinases and stress signaling in
cancer. EMBO Rep 3:420–425
Berenblum I (1982) Sequential aspects of chemical carcinogenesis skin. In: Becker FF (ed) Cancer:
a comprehesive treatise, vol 1, 2nd edn. Plenum Publ. Corp, New York
Charaka (700 BC) Charaka Samhita. Chaukhamba Orientalia, Varanasi
Cho BJ, Im EK, Kwon JH, Lee KH, Shin HJ, Oh J, Kang SM, Chung JH, Jang Y (2005) Berberine
inhibits the production of lysophosphatidylcholine-induced reactive oxygen species and the
ERK1/2 pathway in vascular smooth muscle cells. Mol Cell 20:429–434
Craig WJ (1997) Phytochemicals: guardians of our health. J Am Diet Assoc 97:S199–S204
Craig WJ (1999) Health-promoting properties of common herbs. Am J Clin Nutr 70:491S–499S
Devi PU (1996) Withania somnifera Dunal (Ashwagandha): potential plant source of a promising
drug for cancer chemotherapy and radiosensitization. Indian J Exp Biol 34:927–932
Dorman HJ, Kosar M, Kahlos K, Holm Y, Hiltunen R (2003) Antioxidant properties and composition of aqueous extracts from Mentha species, hybrids, varieties and cultivars. J Agric Food
Chem 51:4563–4569
Dreosti IE (1996) Bioactive ingredients: antioxidants and polyphenols in tea. Nutr Rev
54:S51–S58
Du Q, Hu B, An HM, Shen KP, Xu L, Deng S, Wei MM (2013) Synergistic anticancer effects of
curcumin and RESV in Hepa1-6 hepatocellular carcinoma. Oncol Rep 29:1851–1858
El-Zayat AAE, Degen D, Drabek S, Clark GM, Pettit GR, Von Hoff DD (1993) In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum
Caffrum (arid shrub). Anti-Cancer Drugs 4:19–25
Gaidhani SN, Singh A, Kumari S, Lavekar GS, Juvekar AS, Sen S, Padhi MM (2013) Evaluation
of some plant extracts for standardization and anticancer activity. Indian J Tradit Knowl
12:682–687
Garodia P, Ichikawa H, Malani N, Sethi G, Aggarwal BB (2007) From ancient medicine to modern
medicine: ayurvedic concepts of health and their role in inflammation and cancer. J Soc Integr
Oncol 5(1 Winter):25–37
Glaser T, Winter S, Groscurth P, Safayhi H, Sailer ER, Ammon HP, Schabet M, Weller M (1999)
Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 80:756–765
Greenwell M, Rahman PKSM (2015) Medicinal plants: their use in anticancer treatment. Int
J Pharm Sci Res 6:4103–4112
Guyton KZ, Liu Y, Gorospe M, Xu Q, Holbrook NJ (1996) Activation of mitogen-activated protein
kinase by H2O2: role in cell survival following oxidant injury. J Biol Chem 271:4138–4142
Hamel E, Lin CM (1983) Interactions of combretastatin: a new plantderived antimitotic agent,
with tubulin. Biochem Pharmacol 32:3864–3867
Hansen JM, Go YM, Jones DP (2006) Nuclear and mitochondrial compartmentation of oxidative
stress and redox signaling. Annu Rev Pharmacol Toxicol 46:215–234
A. Augustine and G.S. Pillai