This series represents critical reviews on the present and future trends in
Biochemical Engineering/Biotechnology, including microbiology, genetics,
biochemistry, chemistry, computer science and chemical engineering. It is
addressed to all scientists at universities and in industry who wish to keep upto-date in this.extremly fast developing area of science.
In general, special volumes are dedicated to selected topics and are edited
by well known guest editors. The managing editor and publisher will however
always be pleased to receive suggestions and supplementary information.
Manuscripts are accepted in English.
In references Advances in Biochemical Engineering/Biotechnology is
abbreviated as Adv. Biochem. Engin./Biotechnol. as a journal.
ISBN3-540-63417-7 Springer-Verlag Berlin HeidelbergNewYork
Library of Congress Catalog Card Number 72-152360
This work is subject to copyright. All rights are reserved, whether the whole or part of
the material is concerned, specifically the rights of translation, reprinting, re-use of
illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and
storage in data banks. Duplication of this publication or parts thereof is only permitted
under the provisions of the German Copyright Law of September 9, 1965, in its current
version, and a copyright fee must always be paid.
9 Springer-Verlag Berlin Heidelberg 1998
ISSN 0724-6145
Printed in Germany
The use of registered names, trademarks, etc. in this publication does not imply, even
in the absence of a specific statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
Typesetting: Macmillan IndiaLtd., Bangalore-25
SPIN: 10573576
02/3020-5432 1 0-Printedonacid-freepaper
Biochemical Engineering/Biotechnology, including microbiology, genetics,
biochemistry, chemistry, computer science and chemical engineering. It is
addressed to all scientists at universities and in industry who wish to keep upto-date in this.extremly fast developing area of science.
In general, special volumes are dedicated to selected topics and are edited
by well known guest editors. The managing editor and publisher will however
always be pleased to receive suggestions and supplementary information.
Manuscripts are accepted in English.
In references Advances in Biochemical Engineering/Biotechnology is
abbreviated as Adv. Biochem. Engin./Biotechnol. as a journal.
ISBN3-540-63417-7 Springer-Verlag Berlin HeidelbergNewYork
Library of Congress Catalog Card Number 72-152360
This work is subject to copyright. All rights are reserved, whether the whole or part of
the material is concerned, specifically the rights of translation, reprinting, re-use of
illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and
storage in data banks. Duplication of this publication or parts thereof is only permitted
under the provisions of the German Copyright Law of September 9, 1965, in its current
version, and a copyright fee must always be paid.
9 Springer-Verlag Berlin Heidelberg 1998
ISSN 0724-6145
Printed in Germany
The use of registered names, trademarks, etc. in this publication does not imply, even
in the absence of a specific statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
Typesetting: Macmillan IndiaLtd., Bangalore-25
SPIN: 10573576
02/3020-5432 1 0-Printedonacid-freepaper