2
J. Gomes and A.S. Menawat
8 Control Strategy for Bioproduction ................................
36
9 Conclusions and Future Prospects ................................
39
10 Appendix ...............................................
41
11 References ...............................................
45
List of Symbols and Abbreviations
a
A*
A
b
C
9
Ke
Kel
Ke2
Ki
Kil
Ki2
kta
K,,,
P
S
7?0
1)
V
Y
YCA
Ycs
YP1A
YP2A
YPls
YP2S
FIA
HPLC
PHB
GC
EDR
OUR
constant for activation term
saturated dissolved oxygen concentration (g 1-1)
dissolved oxygen concentration (g 1-:)
constant for activation term
cell mass concentration (g 1-l)
glucose concentration
exponential model constant (g 1-1)
exponential model constant for product 1 (g 1-1)
exponential model constant for product 2 (g 1-1)
inhibition constant for Haldane-Monod or exponential structures
(g1-1)
inhibition constant for product 1 in exponential model (g 1-:)
inhibition constant for product 2 in exponential model (g 1- l)
mass transfer coefficient (h-a)
Monod constant (g 1-1)
product concentration (g 1-1)
substrate concentration (g 1- x)
feed concentration (g 1-1)
time of glucose feed initiation (hr)
volumetric air flow rate (1 min-1)
volume (1)
yield coefficient [(cell mass concentration (g 1-1))/(substrate concentration (g 1-1))]
yield coefficient of cell mass based on oxygen (g cell mass)/(g oxygen)
yield coefficient of cell mass from substrate (g cell mass)/(g substrate)
yield coefficient of product 1 based on oxygen (g product 1)/(g oxygen)
yield coefficient of product 2 based on oxygen (g product 2)/(g oxygen)
yield coefficient of product 1 based on substrate (g product 1)/(g substrate)
yield coefficient of product 2 based on substrate (g product 2)/(g substrate)
flow injection analysis
high pressure liquid chromatography
poly-fl-hydroxybutyric
gas chromatography
external differential representation
oxygen uptake rate