338
P. M. RUDD et al.
Deisenhofer J (1981) Crystallographic refinement and atomic models of a human Fc fragment and its
complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.
Biochemistry 20: 2361-2370
Duncan AR, Woof JM, Partridge LJ, Burton DR, Winter G (1988) Localization of the binding site for
the human high-affinity Fc receptor on IgG. Nature 332: 563-564
Dustin ML, Ferguson LM, Chan PY, Springer TA, Golan DE (1996) Visualization of CD2 interaction
with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors
in a contact area. J Cell Bioi 132: 456-474
Field MC, Amatayakul-Chantler S, Rademacher TW, Rudd PM, Dwek, RA (1994) Structural analysis
of the N -glycans from human immunoglobulin AI: comparison of normal human serum immunoglobulin Al with that isolated from patients with rheumatoid arthritis. Biochem J 299: 261-275
Fletcher CM, Harrison RA, Lachmann PJ, Neuhaus D (1994) Structure of a soluble, glycosylated form
of the human complement regulatory protein CD59. Current Biology Structure 2: 185-199
Friedrichson T, Kurzchalia TV (1998) Microdomains of GPI-anchored proteins in living cells revealed
by crosslinking. Nature 394: 802-804
Gao GF, Tormo J, Gerth UC, Wyer JR, McMichael AI, Stuart DI, Bell JI, Jones EY, Jakobsen BK (1997)
Crystal structure of the complex between human CD8a (alpha) and HLA-A2. Nature 387: 630-634
Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA
(1996) An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science 274: 209-219
Kuster B, Wheeler SF, Hunter AP, Dwek RA, Harvey DJ (1997) Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography.
Anal Biochem 250: 82 - 101
Kuttner-Kondo L, Medof ME, Brodbeck W, Shoham M (1996) Molecular modeling and mechanism of
action of human decay-accelerating factor. Protein Eng 9: 1143-1149
Leader KA, Lastra GC, Kirwan JR, Elson Cj (1996) Agalactosyl IgG in aggregates from the rheumatoid
joint. Br J Rheumatol 35: 335-341
Leatherbarrow RJ, Dwek RA (1984) Binding of complement subcomponent Clq to mouse IgGl, IgG2a
and IgG2b: a novel Clq binding assay. Molecular Immunology 21: 321-327
Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB (1995) Glycosylation changes of
IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nature Medicine 1: 237-241
Mattu TS, Woof J M, Lellouch A, Rudd PM, Dwek, RA (1998) The glycosylation and structure of
human serum IgAl, Fab, and Fc regions and the role ofN-glycosylation on Fc alpha receptor interactions. J Bioi Chern 273: 2260-2272
McConville MJ, Ferguson MAJ (1993) The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes. Biochem J 294: 305-324
Mestecky J, Kilian M (1985) Immunoglobulin A (IgA). Methods Enzymol116: 37-75
Ninomiya H, Stewart BH, Rollins SA, Zhao J, Bothwell ALM, Sims PJ (1992) Contribution of the Nlinked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity. J Bioi
Chern 267: 8404-84lO
Nose M, Wigzell H (1983) Biological significance of carbohydrate chains on monoclonal antibodies.
Proc Nat Acad Sci USA 80: 6632-6636
Padlan EA (1994) Anatomy of the antibody molecule. Mol Immunol 31: 169-217
Parekh RB, Dwek RA, Sutton BJ, Fernandes DL, Leung A, Stanworth D, Rademacher TW, Mizuochi T,
Taniguchi T, Matsuta K, Takeuchi F, Nagano Y, Miyamoto T, Kobata A (1985) Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total
serum IgG. Nature 316: 452-457
Parekh RB, Isenberg D, Rook G, Roitt I, Dwek RA, Rademacher TW (1989) A comparative analysis of
disease-associated changes in the galactosylation of serum IgG. J Autoimmunity 2: 101-114
Recny MA, Luther MA, Knoppers MH, Neinhardt EA, Khandekar SS, Concino MF, Schimke, PA, Francis MA, Moebius U, Reinhold B, Reinhold VN, Reinherz EL (1992) N-glycosylation is required for
human CD2 immunoadhesion functions. J Bioi Chern 267: 22428-22434
Rudd PM, Guile GR, Kuster B, Harvey DJ, Opdenakker G, Dwek RA (1997) Oligosaccharide Sequencing Technology. Nature 388: 205-208
Rudd PM, Leatherbarrow RJ, Rademacher TW and Dwek RA (1991) Diversification of the IgG molecule by oligosaccharides. Molecular Immunol 28: 1369-1378
Rudd PM, Joao HC, Coghill E, Fiten P, Saunders MR, Opdenakker G, Dwek RA (1994) Glycoforms
modify the dynamic stability and functional activity of an enzyme. Biochemistry 33: 17 -22
P. M. RUDD et al.
Deisenhofer J (1981) Crystallographic refinement and atomic models of a human Fc fragment and its
complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.
Biochemistry 20: 2361-2370
Duncan AR, Woof JM, Partridge LJ, Burton DR, Winter G (1988) Localization of the binding site for
the human high-affinity Fc receptor on IgG. Nature 332: 563-564
Dustin ML, Ferguson LM, Chan PY, Springer TA, Golan DE (1996) Visualization of CD2 interaction
with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors
in a contact area. J Cell Bioi 132: 456-474
Field MC, Amatayakul-Chantler S, Rademacher TW, Rudd PM, Dwek, RA (1994) Structural analysis
of the N -glycans from human immunoglobulin AI: comparison of normal human serum immunoglobulin Al with that isolated from patients with rheumatoid arthritis. Biochem J 299: 261-275
Fletcher CM, Harrison RA, Lachmann PJ, Neuhaus D (1994) Structure of a soluble, glycosylated form
of the human complement regulatory protein CD59. Current Biology Structure 2: 185-199
Friedrichson T, Kurzchalia TV (1998) Microdomains of GPI-anchored proteins in living cells revealed
by crosslinking. Nature 394: 802-804
Gao GF, Tormo J, Gerth UC, Wyer JR, McMichael AI, Stuart DI, Bell JI, Jones EY, Jakobsen BK (1997)
Crystal structure of the complex between human CD8a (alpha) and HLA-A2. Nature 387: 630-634
Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA
(1996) An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science 274: 209-219
Kuster B, Wheeler SF, Hunter AP, Dwek RA, Harvey DJ (1997) Sequencing of N-linked oligosaccharides directly from protein gels: in-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography.
Anal Biochem 250: 82 - 101
Kuttner-Kondo L, Medof ME, Brodbeck W, Shoham M (1996) Molecular modeling and mechanism of
action of human decay-accelerating factor. Protein Eng 9: 1143-1149
Leader KA, Lastra GC, Kirwan JR, Elson Cj (1996) Agalactosyl IgG in aggregates from the rheumatoid
joint. Br J Rheumatol 35: 335-341
Leatherbarrow RJ, Dwek RA (1984) Binding of complement subcomponent Clq to mouse IgGl, IgG2a
and IgG2b: a novel Clq binding assay. Molecular Immunology 21: 321-327
Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB (1995) Glycosylation changes of
IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nature Medicine 1: 237-241
Mattu TS, Woof J M, Lellouch A, Rudd PM, Dwek, RA (1998) The glycosylation and structure of
human serum IgAl, Fab, and Fc regions and the role ofN-glycosylation on Fc alpha receptor interactions. J Bioi Chern 273: 2260-2272
McConville MJ, Ferguson MAJ (1993) The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes. Biochem J 294: 305-324
Mestecky J, Kilian M (1985) Immunoglobulin A (IgA). Methods Enzymol116: 37-75
Ninomiya H, Stewart BH, Rollins SA, Zhao J, Bothwell ALM, Sims PJ (1992) Contribution of the Nlinked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity. J Bioi
Chern 267: 8404-84lO
Nose M, Wigzell H (1983) Biological significance of carbohydrate chains on monoclonal antibodies.
Proc Nat Acad Sci USA 80: 6632-6636
Padlan EA (1994) Anatomy of the antibody molecule. Mol Immunol 31: 169-217
Parekh RB, Dwek RA, Sutton BJ, Fernandes DL, Leung A, Stanworth D, Rademacher TW, Mizuochi T,
Taniguchi T, Matsuta K, Takeuchi F, Nagano Y, Miyamoto T, Kobata A (1985) Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total
serum IgG. Nature 316: 452-457
Parekh RB, Isenberg D, Rook G, Roitt I, Dwek RA, Rademacher TW (1989) A comparative analysis of
disease-associated changes in the galactosylation of serum IgG. J Autoimmunity 2: 101-114
Recny MA, Luther MA, Knoppers MH, Neinhardt EA, Khandekar SS, Concino MF, Schimke, PA, Francis MA, Moebius U, Reinhold B, Reinhold VN, Reinherz EL (1992) N-glycosylation is required for
human CD2 immunoadhesion functions. J Bioi Chern 267: 22428-22434
Rudd PM, Guile GR, Kuster B, Harvey DJ, Opdenakker G, Dwek RA (1997) Oligosaccharide Sequencing Technology. Nature 388: 205-208
Rudd PM, Leatherbarrow RJ, Rademacher TW and Dwek RA (1991) Diversification of the IgG molecule by oligosaccharides. Molecular Immunol 28: 1369-1378
Rudd PM, Joao HC, Coghill E, Fiten P, Saunders MR, Opdenakker G, Dwek RA (1994) Glycoforms
modify the dynamic stability and functional activity of an enzyme. Biochemistry 33: 17 -22