The Rate-Determining Step in the S N Ar Reaction 223
]
H
[DNFB][ArNH H
]
[ArNH
+
+
])
[ArNH
(
2
2
3
1
2
2
3
2
1
=
k 3
k
k
k 3
k 2
k 1
v
(33.1)
were,
>
@
>
@
>
@
3
2
1
1
obs
k 3
k 2
k
k 1
k o
This problem is based on the work by Persson J, Matsson O (1998) J. Org.
Chem. 63:9348-9350 and the work by Onydo I, Hirst J (1991) J. Phys. Org. Chem.
4:367-371.
Subjects of Revision
S N Ar mechanism. Rate-determining step. Steady state approximation. Kinetic isotope effects.
]
H
[DNFB][ArNH H
]
[ArNH
+
+
])
[ArNH
(
2
2
3
1
2
2
3
2
1
=
k 3
k
k
k 3
k 2
k 1
v
(33.1)
were,
>
@
>
@
>
@
3
2
1
1
obs
k 3
k 2
k
k 1
k o
This problem is based on the work by Persson J, Matsson O (1998) J. Org.
Chem. 63:9348-9350 and the work by Onydo I, Hirst J (1991) J. Phys. Org. Chem.
4:367-371.
Subjects of Revision
S N Ar mechanism. Rate-determining step. Steady state approximation. Kinetic isotope effects.