CHAPTER 17 • Characterization of Marine Toxins with LC-ESI-MS
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Three different classes of polyether toxins have been found to cause DSP, namely
i. okadaic acid (OA) and its derivatives dinophysistoxins (DTXs),
ii. pectenotoxins (PTXs), and
iii. yessotoxins (YTXs).
whose structures are shown in Fig. 17.1.
0"'"
""'OR,
CH 3
R,
R2
Okadaic acid (OA)
H
H
Dinophysistoxin-l (DTX-l)
H
CH 3
Dinophysistoxin-2 (DTX-2)
H
CH 3
Dinophysistoxin-3 (DTX-3)
Acyl
CH 3
Pectenotoxins
PTX-2
R=CH 3
o
PTX-3
R=CHO
Yessotoxins
R=H,OH
R3
CH 3
CH 3
H
H
OH
H
PTX-6
R=COOH
Fig. 17.1. Chemical structures of some common DSP toxins
OH