CHAPTER 12 . 119Sn Mossbauer Spectroscopy Studies: Organotin(lV) Salts and Complexes
241
These results are interpreted as follows (Barbieri 1995):
i. Systems NO.1, Table 12.6: the cysteine, as well as mercaptocarboxylic acid, moiety,
interact with DNA, according to the general trends mentioned here in the preceding; ternary systems are formed, preferentially with respect to the interaction of Sn
with DNA phosphodiester.
ii. In system NO.3, cysteine binds to DNA in the general way for amino acids-nucleic
acid systems (vide supra). Then, the subsequent addition of ethanolic Et2SnCl2 yields
the common DNA condensate by Et 2 Sn(IV) phospho diester binding.
References
Arakawa Y (1998) Recent studies on the mode of biological action of di- and tri-alkyltin compounds.
In: Smith PI (ed) Chemistry of tin. Blackie Acad and Prof, London, pp 388-428
Baczynskyj L, Biemann K, Hall RH (1968) Sulfur-containing nucleoside from yeast transfer ribonucleic acid: 2-thio-5 (or 6) -uridine acetic acid methyl ester. Science 159:1481-1483
Barbieri A (1995) Sintesi e caratterizzazione di complessi di Sn(IV), RnSn(IV) e Fe(II,III). Studio
dell'interazione di AlknSn(IV) con DNA nativo (Alk= Me, Et; n = 2,3). Thesis for Ph.D. degree, University of Palermo
Barbieri A, Giuliani AM, Ruisi G, Silvestri A, Barbieri R (1995) Tin(IV), monomethyltin(IV) and
dimethyltin(IV) complexes with thiol sulphur and heterocyclic nitrogen donors: Molecular dynamics and structure by 119Sn Mossbauer spectroscopy. Z Anorg Allg Chern 621:89-96
Barbieri R (1956) Separazione e dosaggio dei mononucleotidi degli acidi nucleici del fegato; ricerche
sulla incorporazione di fosfato marcato con 32p. Thesis for Master degree in Chemistry, University
of Padua
Barbieri R, Musmeci MT (1988) A 119Sn Mossbauer spectroscopic study on the interaction of
dimethyltin(IV) derivatives with rat hemoglobin, and of related model systems in aqueous solution. I Inorg Biochem 32:89-108
Barbieri R, Silvestri A (1984) The correlation between tin-119 Mossbauer isomer shifts and atomic
charges on tin in five-coordinated tin(IV) derivatives. I Chern Soc Dalton Trans 1019-1025
Barbieri R, Silvestri A (1991) The interaction of native DNA with dimethyltin(IV) species. I Inorg
Biochem 41:31-35
Barbieri R, Belluco U, Tagliavini G (1958) Separazione cromatografica su carta di composti metallorganici di piombo e stagno. Annali di Chimica 48:940-949
Barbieri R, Alonzo G, Herber RH (1987) Configuration and lattice dynamics of complexes of
diaikyltin(IV) with adenosine-5'-monophosphate and phenyl phosphates. J Chern Soc Dalton Trans
789-794
Barbieri R, Silvestri A, Filippeschi S, Magistrelli M, Huber F (1990) Studies on the antitumor activity
of complexes of R2Sn(IV) with penicillamine enantiomers and with 3-thio-propanoic acid, and
correlation with structural aspects. Inorg Chim Acta 177:141-144
Barbieri R, Silvestri A, Giuliani AM, Piro V, Di Simone F, Madonia G (1992) Organotin compounds
and deoxyribonucleic acid. I Chern Soc Dalton Trans 585-590
Barbieri R, Ruisi G, Silvestri A, Giuliani AM, Barbieri A, Spina G, Pieralli F, Del Giallo F (1995) Dynamics of tin nuclei in alkyltin(IV)-deoxyribonucleic acid condensates by variable temperature
tin-u9 Mossbauer spectroscopy. I Chern Soc Dalton Trans 467-475
Barbieri R, Huber F, Pellerito L, Ruisi G, Silvestri A (1998) 119-m Sn Mossbauer studies on tin compounds. In: Smith PJ (ed) Chemistry of tin. Blackie Acad and Prof, London, pp 496-540
Barbieri R, Huber F, Silvestri A, Ruisi G, Rossi M, Barone G, Barbieri Paulsen A (1999) The interaction
of S, N-coordinated dimethyltin(IV) derivatives with deoxyribonucleic acid: structure and dynamics by 119Sn Mossbauer spectroscopy. Appl Organometal Chern 13:595-603
Barone G (1997) Interazione di acido deossiribonucleico (DNA), e mole cole costituenti, con
(CH3)nSn(IV) (n = 1-3). Thesis for Ph.D. Degree in Chemistry, University of Palermo
Bauer C, Wang AHJ (1997) Bridged cobalt amine complexes induce DNA conformational changes effectively. J Inorg Biochem 68:129-135
Berthon G (1995) Handbook of metal-ligand interactions in biological fluids. M Dekker, New York
Black CB, Huang HW, Cowan JA (1994) Biological coordination chemistry of magnesium, sodium,
and potassium ions. Protein and nucleotide binding sites. Coord Chern Revs 135/136:165-202
Bloomfield V A (1996) DNA condensation. Current Opinion in Struct Bioi 6:334-341
241
These results are interpreted as follows (Barbieri 1995):
i. Systems NO.1, Table 12.6: the cysteine, as well as mercaptocarboxylic acid, moiety,
interact with DNA, according to the general trends mentioned here in the preceding; ternary systems are formed, preferentially with respect to the interaction of Sn
with DNA phosphodiester.
ii. In system NO.3, cysteine binds to DNA in the general way for amino acids-nucleic
acid systems (vide supra). Then, the subsequent addition of ethanolic Et2SnCl2 yields
the common DNA condensate by Et 2 Sn(IV) phospho diester binding.
References
Arakawa Y (1998) Recent studies on the mode of biological action of di- and tri-alkyltin compounds.
In: Smith PI (ed) Chemistry of tin. Blackie Acad and Prof, London, pp 388-428
Baczynskyj L, Biemann K, Hall RH (1968) Sulfur-containing nucleoside from yeast transfer ribonucleic acid: 2-thio-5 (or 6) -uridine acetic acid methyl ester. Science 159:1481-1483
Barbieri A (1995) Sintesi e caratterizzazione di complessi di Sn(IV), RnSn(IV) e Fe(II,III). Studio
dell'interazione di AlknSn(IV) con DNA nativo (Alk= Me, Et; n = 2,3). Thesis for Ph.D. degree, University of Palermo
Barbieri A, Giuliani AM, Ruisi G, Silvestri A, Barbieri R (1995) Tin(IV), monomethyltin(IV) and
dimethyltin(IV) complexes with thiol sulphur and heterocyclic nitrogen donors: Molecular dynamics and structure by 119Sn Mossbauer spectroscopy. Z Anorg Allg Chern 621:89-96
Barbieri R (1956) Separazione e dosaggio dei mononucleotidi degli acidi nucleici del fegato; ricerche
sulla incorporazione di fosfato marcato con 32p. Thesis for Master degree in Chemistry, University
of Padua
Barbieri R, Musmeci MT (1988) A 119Sn Mossbauer spectroscopic study on the interaction of
dimethyltin(IV) derivatives with rat hemoglobin, and of related model systems in aqueous solution. I Inorg Biochem 32:89-108
Barbieri R, Silvestri A (1984) The correlation between tin-119 Mossbauer isomer shifts and atomic
charges on tin in five-coordinated tin(IV) derivatives. I Chern Soc Dalton Trans 1019-1025
Barbieri R, Silvestri A (1991) The interaction of native DNA with dimethyltin(IV) species. I Inorg
Biochem 41:31-35
Barbieri R, Belluco U, Tagliavini G (1958) Separazione cromatografica su carta di composti metallorganici di piombo e stagno. Annali di Chimica 48:940-949
Barbieri R, Alonzo G, Herber RH (1987) Configuration and lattice dynamics of complexes of
diaikyltin(IV) with adenosine-5'-monophosphate and phenyl phosphates. J Chern Soc Dalton Trans
789-794
Barbieri R, Silvestri A, Filippeschi S, Magistrelli M, Huber F (1990) Studies on the antitumor activity
of complexes of R2Sn(IV) with penicillamine enantiomers and with 3-thio-propanoic acid, and
correlation with structural aspects. Inorg Chim Acta 177:141-144
Barbieri R, Silvestri A, Giuliani AM, Piro V, Di Simone F, Madonia G (1992) Organotin compounds
and deoxyribonucleic acid. I Chern Soc Dalton Trans 585-590
Barbieri R, Ruisi G, Silvestri A, Giuliani AM, Barbieri A, Spina G, Pieralli F, Del Giallo F (1995) Dynamics of tin nuclei in alkyltin(IV)-deoxyribonucleic acid condensates by variable temperature
tin-u9 Mossbauer spectroscopy. I Chern Soc Dalton Trans 467-475
Barbieri R, Huber F, Pellerito L, Ruisi G, Silvestri A (1998) 119-m Sn Mossbauer studies on tin compounds. In: Smith PJ (ed) Chemistry of tin. Blackie Acad and Prof, London, pp 496-540
Barbieri R, Huber F, Silvestri A, Ruisi G, Rossi M, Barone G, Barbieri Paulsen A (1999) The interaction
of S, N-coordinated dimethyltin(IV) derivatives with deoxyribonucleic acid: structure and dynamics by 119Sn Mossbauer spectroscopy. Appl Organometal Chern 13:595-603
Barone G (1997) Interazione di acido deossiribonucleico (DNA), e mole cole costituenti, con
(CH3)nSn(IV) (n = 1-3). Thesis for Ph.D. Degree in Chemistry, University of Palermo
Bauer C, Wang AHJ (1997) Bridged cobalt amine complexes induce DNA conformational changes effectively. J Inorg Biochem 68:129-135
Berthon G (1995) Handbook of metal-ligand interactions in biological fluids. M Dekker, New York
Black CB, Huang HW, Cowan JA (1994) Biological coordination chemistry of magnesium, sodium,
and potassium ions. Protein and nucleotide binding sites. Coord Chern Revs 135/136:165-202
Bloomfield V A (1996) DNA condensation. Current Opinion in Struct Bioi 6:334-341