Glycosyl Trichloroacetimidates
3.2
483
⊡ Scheme 19
shown in > Scheme 19 [132]. Glycosyl donor 19a, also obtained via the trichloroacetimidate
method, gave with acceptor 19b pentasaccharide 19c. Standard transformation via 19d, 19e,
and 19f led to pentasaccharide donor 19g. Application of the azidosphingosine glycosylation
procedure with 19h as acceptor furnished 19i which was transformed via 19j into the target
molecule 19k.
Further, for microdomain formation studies fluorescence labeled sialyl Lewis X [133], for
cluster effect studies dimeric sialyl Lewis X [134], and for carbohydrate–carbohydrate recognition studies a dimer of Lewis X [135] were synthesized ( > Scheme 20, 20k). To this aim,
3.2
483
⊡ Scheme 19
shown in > Scheme 19 [132]. Glycosyl donor 19a, also obtained via the trichloroacetimidate
method, gave with acceptor 19b pentasaccharide 19c. Standard transformation via 19d, 19e,
and 19f led to pentasaccharide donor 19g. Application of the azidosphingosine glycosylation
procedure with 19h as acceptor furnished 19i which was transformed via 19j into the target
molecule 19k.
Further, for microdomain formation studies fluorescence labeled sialyl Lewis X [133], for
cluster effect studies dimeric sialyl Lewis X [134], and for carbohydrate–carbohydrate recognition studies a dimer of Lewis X [135] were synthesized ( > Scheme 20, 20k). To this aim,