Glycosyl Halides
3.1
431
⊡ Table 1
Glycosylation of glycosyl bromide or chloride using heavy metal
Activator
Acid scavenger Drying agent
Ref.
AgClO 4
Ag 2 CO 3
Drierite
[4a–h, j, l,5]
AgOTf
Ag 2 O
molecular sieves
AgNO 3
HgO
Ag 2 CO 3
CdCO 3
Ag 2 O
s-collidine
Ag-silicate
TMU
Hg(CN)
HgBr 2
HgCl 2
HgI 2
⊡ Table 2
Glycosylation of glycosyl bromide or chloride using Lewis acid
Activator
X
Ref.
SnCl 4
SnBu 3
[8]
BF 3 ·OEt 2
SnBu 3
[8]
Sn(OTf) 2 -collidine
H
[9a]
Sn(OTf) 2 -TMU
H
[9b]
TrCl-ZnCl 2
H
[10]
LiClO 4
H
[11]
I 2 -DDQ
H
[12]
IBr
H
[13]
NIS
H
[14]
In
H
[15]
InCl 3
H
[16]
TMSOTf
SnBu 3
[17]
H
[18,19]
Zn(acac) 2
H
[20]
H
[21]
Cu(OTf) 2 -BTF
H
[22]