14
H. Wyman Dorough and Sue K. Ballard
PESTICIDE
AGLYCONE
CONJUGATE
CIOh )-CI CI-< )-~-< )-CI
O-GLUCURON IDE
CCI J
. . . . c,
0 .... OH
DDT
II
S O
(C2H50)fP-S ~
j CI
CI-<
)-SH
S-GLUCURONIDE
STAUFfER N-2596
CI
b- CH
D- ~H3 r H 3
I J
F \.
~-CH-COOC\H
f \.
I ~:~H-COOH
O-GLUCU RON IDE
(5 CH 3
0
f LAMPROP-ISOPROPY L
HO
o 0 CH o 0 CH
"
I
J
"
I 3
\.
NH-C-O-C,H
\.
NH-C-O-C,H
O-GLUCURON I DE
CH 3
CH 3
PROPHAM
C tH
0
0
I I
I NH
N-GLUCURON I De
H3C
/
H3 C
0/
0
TACHIGAREN
GH3)2NJ-~:.
5
(
II
•
S!GLUCURONIDE
CHJ)iN-C-S H
FERBAM
Figure 1.13. Examples of pesticides which undergo glucuronide metabolism in animals.