Immune system of Cyprinid fish
435
by
the pharyngeal epithelium.
Histologically there is a faint cortex—
differentiation (Manning et al., 1982b;
Van Loon et al., 1982).
The
is
the
first lymphoid organ to appear during ontogeny (Botham & Man—
1981;
Van Loon et al., 1982), and can be regarded as a central lymphoid
Unlike
secondary lymphoid organs the thymus is not involved in antigen
antibody production (Rijkers et al., 1980b).
_
,
ÊhÊ_Spleen in cyprinid fish is a haemopoietic organ, inlcuding -diffuse1y
lymphoid tissue;
it does not contain distinct white pulp compart—
(Haider, 1966;
Lamers
& De Haas, 1985).
elements
of
carp
are
the ellipsoids and MMCs (Graf & Schluns, 1979;
Lamers
& De Haas,
7,1985).
ËhÊ_kidney is an important lympho—myeloid organ in carp,
it
is
divided
head
kidney
and trunk kidney (pronephros and opisthonephros), of Which
the head kidney has lost its excretory functionThe lymphoid
tissue
has
a
little
patterned
arrangement,
although lymphoid cells usually cluster along
or
arteries.
As
in spleen MMCs are present throughout the organs (Smith
al., 1970;
Lamers
& De
Haas, 1985).
.
ku
The kidney has a high capacity of lympho— and plasmacytopoiesis (Smith et
1970;
Zapata, 1981).
Following antigenic stimulation, both kidney and
are
involved in antigen processing and
antibody
production,« however,
the
contribution of the different organs
to
the total.number of an—
“
tibody producing cells, the contribution of the
Spleen.
is
relatively: small
“f(5%) when compared to that of kidney (93%;
*Rijkers et al.,
-
'%u:
Intestine.
In teleosts, leucocytes are present in the epithelium as well
as
in
the
lamine proprice of the gut.
In carp and rosy barb mainly lymphocytes and heterophilic
granulocytes
were
observed
(Davina
et
al.,
1980;
1982)The
total
number of cells is considerable;
it ranges
from 20 to 50
leucocytes per 100 epithelial cells in rosy barb (Davina et al.,
as
in
1
year old carp the number varied from 90 to 130 (Lamers, unpublished
At a rough estimate 100—300 x lO*8,leucocytes will
present
in
intestinal epithelium of 1 year old carp.
NotWithstanding these numbers,
even
might surpass the numbers of leucocytes in other
only
limited number of reports are dealing With intestinal immunity in cypfish…
Davina et
(1982) reported that oral intubation;of;rosyf_barb
Vibrio anguillarum bactèrin induced an inflâmmatory reaction in the sec—
gut segment.
Rombout'et
antigens may
through— the
and contact intra epithelial macrophages and lymphocyteS-ë
près—
both macrophages ând
specific immunological
cells haye be?“ de—
both
in the
13mlna
reach
Recently it
edf
in
increase of specific
ëËd
eas
did not influence
tem in carp.
5
€XÊêÿlng
ww)aggregates
(Mori,
*
«
on ;. reticular
fibres
,_
Wh@ïe they are retalned f°rs°me
f “Weeks (Sèc0mbèè
989 ;;
:; 1952bà»v 0nthecontrary
,.
_
…
435
by
the pharyngeal epithelium.
Histologically there is a faint cortex—
differentiation (Manning et al., 1982b;
Van Loon et al., 1982).
The
is
the
first lymphoid organ to appear during ontogeny (Botham & Man—
1981;
Van Loon et al., 1982), and can be regarded as a central lymphoid
Unlike
secondary lymphoid organs the thymus is not involved in antigen
antibody production (Rijkers et al., 1980b).
_
,
ÊhÊ_Spleen in cyprinid fish is a haemopoietic organ, inlcuding -diffuse1y
lymphoid tissue;
it does not contain distinct white pulp compart—
(Haider, 1966;
Lamers
& De Haas, 1985).
elements
of
carp
are
the ellipsoids and MMCs (Graf & Schluns, 1979;
Lamers
& De Haas,
7,1985).
ËhÊ_kidney is an important lympho—myeloid organ in carp,
it
is
divided
head
kidney
and trunk kidney (pronephros and opisthonephros), of Which
the head kidney has lost its excretory functionThe lymphoid
tissue
has
a
little
patterned
arrangement,
although lymphoid cells usually cluster along
or
arteries.
As
in spleen MMCs are present throughout the organs (Smith
al., 1970;
Lamers
& De
Haas, 1985).
.
ku
The kidney has a high capacity of lympho— and plasmacytopoiesis (Smith et
1970;
Zapata, 1981).
Following antigenic stimulation, both kidney and
are
involved in antigen processing and
antibody
production,« however,
the
contribution of the different organs
to
the total.number of an—
“
tibody producing cells, the contribution of the
Spleen.
is
relatively: small
“f(5%) when compared to that of kidney (93%;
*Rijkers et al.,
-
'%u:
Intestine.
In teleosts, leucocytes are present in the epithelium as well
as
in
the
lamine proprice of the gut.
In carp and rosy barb mainly lymphocytes and heterophilic
granulocytes
were
observed
(Davina
et
al.,
1980;
1982)The
total
number of cells is considerable;
it ranges
from 20 to 50
leucocytes per 100 epithelial cells in rosy barb (Davina et al.,
as
in
1
year old carp the number varied from 90 to 130 (Lamers, unpublished
At a rough estimate 100—300 x lO*8,leucocytes will
present
in
intestinal epithelium of 1 year old carp.
NotWithstanding these numbers,
even
might surpass the numbers of leucocytes in other
only
limited number of reports are dealing With intestinal immunity in cypfish…
Davina et
(1982) reported that oral intubation;of;rosyf_barb
Vibrio anguillarum bactèrin induced an inflâmmatory reaction in the sec—
gut segment.
Rombout'et
antigens may
through— the
and contact intra epithelial macrophages and lymphocyteS-ë
près—
both macrophages ând
specific immunological
cells haye be?“ de—
both
in the
13mlna
reach
Recently it
edf
in
increase of specific
ëËd
eas
did not influence
tem in carp.
5
€XÊêÿlng
ww)aggregates
(Mori,
*
«
on ;. reticular
fibres
,_
Wh@ïe they are retalned f°rs°me
f “Weeks (Sèc0mbèè
989 ;;
:; 1952bà»v 0nthecontrary
,.
_
…