v
Preface
this book is focus mainly on vibrational spectroscopy, Raman scattering and infrared absorption, and their applications in biology and medicine. When talking
about new techniques, beside imaging or surface-enhanced spectroscopy also the
investigation of optical activity of the samples became significantly common. In
view of the fact that beside vibrational spectroscopy also electronic absorption is
presented here as a potent and complementary tool to study absolute configuration,
the overall topic of this book is named “optical spectroscopy”, however the main
part is devoted to vibrational methods.
Since the sample investigation is often complicated, especially when a specific
analyte is spread in the biomatrix and occurs in low concentration, it is necessary
to support the analysis by theoretical methods including chemometrics or 2d correlation spectroscopy. demonstrated here approach connecting optical spectroscopy
with computer methods is shown as a powerful tool that can be successfully used in
biology and medicine to study very complex samples.
the book contains a short introduction followed by a set of examples presenting
results obtained by using spectroscopy combined with calculations. New techniques
and its special application are based on Surface-Enhanced Raman Spectroscopy
(SERS), Raman optical Activity (RoA), vibrational Circular dichroism (vCd),
Electronic Circular dichroism (ECd) and matrix isolation spectroscopy. For biological applications the analysis of secondary and primary plant components in the
tissue and single cells is demonstrated. After that, biomedical applications of optical
spectroscopy related to disease diagnosis including the identification of illnesses
biomarkers. A broad qualitative, quantitative and structural study is possible when
the advanced computer methods are used.
malgorzata Baranska
Preface
this book is focus mainly on vibrational spectroscopy, Raman scattering and infrared absorption, and their applications in biology and medicine. When talking
about new techniques, beside imaging or surface-enhanced spectroscopy also the
investigation of optical activity of the samples became significantly common. In
view of the fact that beside vibrational spectroscopy also electronic absorption is
presented here as a potent and complementary tool to study absolute configuration,
the overall topic of this book is named “optical spectroscopy”, however the main
part is devoted to vibrational methods.
Since the sample investigation is often complicated, especially when a specific
analyte is spread in the biomatrix and occurs in low concentration, it is necessary
to support the analysis by theoretical methods including chemometrics or 2d correlation spectroscopy. demonstrated here approach connecting optical spectroscopy
with computer methods is shown as a powerful tool that can be successfully used in
biology and medicine to study very complex samples.
the book contains a short introduction followed by a set of examples presenting
results obtained by using spectroscopy combined with calculations. New techniques
and its special application are based on Surface-Enhanced Raman Spectroscopy
(SERS), Raman optical Activity (RoA), vibrational Circular dichroism (vCd),
Electronic Circular dichroism (ECd) and matrix isolation spectroscopy. For biological applications the analysis of secondary and primary plant components in the
tissue and single cells is demonstrated. After that, biomedical applications of optical
spectroscopy related to disease diagnosis including the identification of illnesses
biomarkers. A broad qualitative, quantitative and structural study is possible when
the advanced computer methods are used.
malgorzata Baranska