5 α-Amino Acids In Water: A Review of VCD and ROA Spectra
139
of surface-enhanced resonance Raman optical activity (SERRoA) have also been
reported [234, 240, 247–249]. It is very probable that the new SERoA techniques
will serve not only as methods yielding spectral fingerprints for different types of
biological molecules and as monitors of chiral surface-analyte interactions, but will
find valuable applications in physico-chemical studies on amino acid-metal surface
interactions.
Finally, there has been significant progress in RoA measurements enabling simultaneous acquisition of all four forms of circular polarisation Raman optical activity. this progress is especially important for dual circular polarisation in-phase
RoA, the most efficient form of RoA that will be important, particularly in biological applications [250].
Acknowledgments this work was partially supported by ICRI (Warsaw) within the framework of statutory activity. Partial support was also provided by grant No. N N204 443 140 of
National Science Centre in Poland. the computational g19-4 grant from the Interdisciplinary
Center of mathematical and Computer modeling (ICm) of the university of Warsaw is also
acknowledged.
Appendix
In table A1, the amino acids together with their precursors are presented. Apart
from their well-known role as building blocks of proteins, the α-amino acids can
form some lipids, act as precursors to other amino acids, metabolites or biologically
active molecules, or have their own bioactivity.
the metabolism of amino acids and the bioactivity of amino acid metabolites is
summed up in table A2.
Some other important facts about the role of free amino acids in organisms are
summarised in table A3; however, an exhaustive description of the topic is beyond
the scope of this chapter. the reader is referred to the literature and biochemical
textbooks [18, 32, 33].
139
of surface-enhanced resonance Raman optical activity (SERRoA) have also been
reported [234, 240, 247–249]. It is very probable that the new SERoA techniques
will serve not only as methods yielding spectral fingerprints for different types of
biological molecules and as monitors of chiral surface-analyte interactions, but will
find valuable applications in physico-chemical studies on amino acid-metal surface
interactions.
Finally, there has been significant progress in RoA measurements enabling simultaneous acquisition of all four forms of circular polarisation Raman optical activity. this progress is especially important for dual circular polarisation in-phase
RoA, the most efficient form of RoA that will be important, particularly in biological applications [250].
Acknowledgments this work was partially supported by ICRI (Warsaw) within the framework of statutory activity. Partial support was also provided by grant No. N N204 443 140 of
National Science Centre in Poland. the computational g19-4 grant from the Interdisciplinary
Center of mathematical and Computer modeling (ICm) of the university of Warsaw is also
acknowledged.
Appendix
In table A1, the amino acids together with their precursors are presented. Apart
from their well-known role as building blocks of proteins, the α-amino acids can
form some lipids, act as precursors to other amino acids, metabolites or biologically
active molecules, or have their own bioactivity.
the metabolism of amino acids and the bioactivity of amino acid metabolites is
summed up in table A2.
Some other important facts about the role of free amino acids in organisms are
summarised in table A3; however, an exhaustive description of the topic is beyond
the scope of this chapter. the reader is referred to the literature and biochemical
textbooks [18, 32, 33].