18 Near-Infrared Spectroscopy in the Pharmaceutical Industry
411
34. A. Kandelbauer, W. Kessler, R.W. Kessler, Online UV–visible spectroscopy and multivariate
curve resolution as powerful tool for model-free investigation of laccase-catalysed oxidation.
Anal. Bioanal. Chem. 390(5), 1303–1315 (2008)
35. P. Hamilton, M.J. Sanganee, J.P. Graham, T. Hartwig, A. Ironmonger, C. Priestley, L.A. Senior,
D.R. Thompson, M.R. Webb, Using PAT to understand, control, and rapidly scale up the
production of a hydrogenation reaction and isolation of pharmaceutical intermediate. Org.
Process Res. Dev. 19(1), 236–243 (2015)
36. M. Blanco, M. Castillo, R. Beneyto, Study of reaction processes by in-line near-infrared spectroscopy in combination with multivariate curve resolution. Esterification of myristic acid with
isopropanol. Talanta. 72(2), 519–525 (2007)
37. M.C. Antunes, J.J. Simão, A.C. Duarte, R. Tauler, Multivariate curve resolution of overlapping
voltammetric peaks: quantitative analysis of binary and quaternary metal mixtures. Analyst.
127(6), 809–817, (2002)
38. J. Wiss, M. Länzlinger, M. Wermuth, Safety improvement of a grignard reaction using on-line
NIR monitoring. Org. Process Res. Dev. 9(3), 365–371 (2005)
39. P.K. Aldridge, C.L. Evans, H.W. Ward Ii, S.T. Colgan, N. Boyer, P.J. Gemperline, Near-IR
detection of polymorphism and process-related substances. Anal. Chem. 68(6), 997–1002
(1996)
40. G. Févotte, J. Calas, F. Puel, C. Hoff, Applications of NIR spectroscopy to monitoring and
analyzing the solid state during industrial crystallization processes. Int. J. Pharm. 273(1–2),
159–169 (2004)
41. S.E. Barnes, T. Thurston, J.A. Coleman, A. Diederich, D. Ertl, J. Rydzak, P. Ng, K. Bakeev,
D. Bhanushali, NIR diffuse reflectance for on-scale monitoring of the polymorphic form transformation of pazopanib hydrochloride (GW786034); model development and method transfer.
Anal. Methods 2(12), 1890–1899 (2010)
42. M. Poux, P. Fayolle, J. Bertrand, D. Bridoux, J. Bousquet, Powder mixing: Some practical rules
applied to agitated systems. Powder Technol. 68(3), 213–234 (1991)
43. A.S. El-Hagrasy, J.K. Drennen, A process analytical technology approach to near-infrared
process control of pharmaceutical powder blending. Part III: quantitative near-infrared calibration for prediction of blend homogeneity and characterization of powder mixing kinetics.
J. Pharm. Sci. 95(2), 422–434 (2006)
44. J.G. Osorio, G. Stuessy, G.J. Kemeny, F.J. Muzzio, Characterization of pharmaceutical powder
blends using in situ near-infrared chemical imaging. Chem. Eng. Sci. 108, 244–257 (2014)
45. P.A. Hailey, P. Doherty, P. Tapsell, T. Oliver, P.K. Aldridge, Automated system for the online monitoring of powder blending processes using near-infrared spectroscopy Part I. System
development and control. J. Pharm. Biomed. Anal. 14(5), 551–559 (1996)
46. B. Igne, A.D. Juan, J. Jaumot, J. Lallemand, S. Preys, J.K. Drennen, C.A. Anderson, Modeling
strategies for pharmaceutical blend monitoring and end-point determination by near-infrared
spectroscopy. Int. J. Pharm. 473(1–2), 219–231 (2014)
47. R. Besseling, M. Damen, T. Tran, T. Nguyen, K. van den Dries, W. Oostra, A. Gerich, An
efficient, maintenance free and approved method for spectroscopic control and monitoring of
blend uniformity: the moving F-test. J. Pharm. Biomed. Anal. 114, 471–481 (2015)
48. S.S. Sekulic, J. Wakeman, P. Doherty, P.A. Hailey, Automated system for the on-line monitoring
of powder blending processes using near-infrared spectroscopy. Part II. Qualitative approaches
to blend evaluation. J. Phar. Biomed. Anal. 17(8), 1285–1309 (1998)
49. G.R. Flåten, R. Belchamber, M. Collins, A.D. Walmsley, Caterpillar—an adaptive algorithm for
detecting process changes from acoustic emission signals. Anal. Chim. Acta. 544(1–2 SPEC.
ISS.), 280–291 (2005)
50. O. Berntsson, L.G. Danielsson, B. Lagerholm, S. Folestad, Quantitative in-line monitoring of
powder blending by near infrared reflection spectroscopy. Powder Technol. 123(2–3), 185–193
(2002)
51. M.A. Alam, Z. Shi, J.K. Drennen, C.A. Anderson, In-line monitoring and optimization of
powder flow in a simulated continuous process using transmission near infrared spectroscopy.
Int. J. Pharm. 526(1–2), 199–208 (2017)
411
34. A. Kandelbauer, W. Kessler, R.W. Kessler, Online UV–visible spectroscopy and multivariate
curve resolution as powerful tool for model-free investigation of laccase-catalysed oxidation.
Anal. Bioanal. Chem. 390(5), 1303–1315 (2008)
35. P. Hamilton, M.J. Sanganee, J.P. Graham, T. Hartwig, A. Ironmonger, C. Priestley, L.A. Senior,
D.R. Thompson, M.R. Webb, Using PAT to understand, control, and rapidly scale up the
production of a hydrogenation reaction and isolation of pharmaceutical intermediate. Org.
Process Res. Dev. 19(1), 236–243 (2015)
36. M. Blanco, M. Castillo, R. Beneyto, Study of reaction processes by in-line near-infrared spectroscopy in combination with multivariate curve resolution. Esterification of myristic acid with
isopropanol. Talanta. 72(2), 519–525 (2007)
37. M.C. Antunes, J.J. Simão, A.C. Duarte, R. Tauler, Multivariate curve resolution of overlapping
voltammetric peaks: quantitative analysis of binary and quaternary metal mixtures. Analyst.
127(6), 809–817, (2002)
38. J. Wiss, M. Länzlinger, M. Wermuth, Safety improvement of a grignard reaction using on-line
NIR monitoring. Org. Process Res. Dev. 9(3), 365–371 (2005)
39. P.K. Aldridge, C.L. Evans, H.W. Ward Ii, S.T. Colgan, N. Boyer, P.J. Gemperline, Near-IR
detection of polymorphism and process-related substances. Anal. Chem. 68(6), 997–1002
(1996)
40. G. Févotte, J. Calas, F. Puel, C. Hoff, Applications of NIR spectroscopy to monitoring and
analyzing the solid state during industrial crystallization processes. Int. J. Pharm. 273(1–2),
159–169 (2004)
41. S.E. Barnes, T. Thurston, J.A. Coleman, A. Diederich, D. Ertl, J. Rydzak, P. Ng, K. Bakeev,
D. Bhanushali, NIR diffuse reflectance for on-scale monitoring of the polymorphic form transformation of pazopanib hydrochloride (GW786034); model development and method transfer.
Anal. Methods 2(12), 1890–1899 (2010)
42. M. Poux, P. Fayolle, J. Bertrand, D. Bridoux, J. Bousquet, Powder mixing: Some practical rules
applied to agitated systems. Powder Technol. 68(3), 213–234 (1991)
43. A.S. El-Hagrasy, J.K. Drennen, A process analytical technology approach to near-infrared
process control of pharmaceutical powder blending. Part III: quantitative near-infrared calibration for prediction of blend homogeneity and characterization of powder mixing kinetics.
J. Pharm. Sci. 95(2), 422–434 (2006)
44. J.G. Osorio, G. Stuessy, G.J. Kemeny, F.J. Muzzio, Characterization of pharmaceutical powder
blends using in situ near-infrared chemical imaging. Chem. Eng. Sci. 108, 244–257 (2014)
45. P.A. Hailey, P. Doherty, P. Tapsell, T. Oliver, P.K. Aldridge, Automated system for the online monitoring of powder blending processes using near-infrared spectroscopy Part I. System
development and control. J. Pharm. Biomed. Anal. 14(5), 551–559 (1996)
46. B. Igne, A.D. Juan, J. Jaumot, J. Lallemand, S. Preys, J.K. Drennen, C.A. Anderson, Modeling
strategies for pharmaceutical blend monitoring and end-point determination by near-infrared
spectroscopy. Int. J. Pharm. 473(1–2), 219–231 (2014)
47. R. Besseling, M. Damen, T. Tran, T. Nguyen, K. van den Dries, W. Oostra, A. Gerich, An
efficient, maintenance free and approved method for spectroscopic control and monitoring of
blend uniformity: the moving F-test. J. Pharm. Biomed. Anal. 114, 471–481 (2015)
48. S.S. Sekulic, J. Wakeman, P. Doherty, P.A. Hailey, Automated system for the on-line monitoring
of powder blending processes using near-infrared spectroscopy. Part II. Qualitative approaches
to blend evaluation. J. Phar. Biomed. Anal. 17(8), 1285–1309 (1998)
49. G.R. Flåten, R. Belchamber, M. Collins, A.D. Walmsley, Caterpillar—an adaptive algorithm for
detecting process changes from acoustic emission signals. Anal. Chim. Acta. 544(1–2 SPEC.
ISS.), 280–291 (2005)
50. O. Berntsson, L.G. Danielsson, B. Lagerholm, S. Folestad, Quantitative in-line monitoring of
powder blending by near infrared reflection spectroscopy. Powder Technol. 123(2–3), 185–193
(2002)
51. M.A. Alam, Z. Shi, J.K. Drennen, C.A. Anderson, In-line monitoring and optimization of
powder flow in a simulated continuous process using transmission near infrared spectroscopy.
Int. J. Pharm. 526(1–2), 199–208 (2017)