484
5 Laser Specklometer, Speckle-Optical Diagnostics and Laser …
same time that creates the most favorable conditions for the regeneration of fibrous
tissues.
High sensitivity of speckle-optical methods of regeneration of hemodynamic
disorders in microcirculatory channel of skin was registered. Dealing with animals
suffering from occlusion of femoral artery progressive decrease of power of spectrum
of fluctuation intensity of speckle-field was observed in comparison with the norm
by 41–67% depending in terms of the operation that is connected with considerable
vasomotor disorders.
A considerable decrease of power spectrum of skin blood flow at the operated
limb during traumatic damage of sciatic nerve with further neurography by 67.3% in
the transmission band of 0–2000 Hz in comparison with intact group was detected.
According to the results of the conducted studies on animals, the application of
intravenous laser blood irradiation ILBI at traumatic damages of peripheral nervous
system decreases trophic disturbances, postponing the time of their appearing in
general. Morphological studies showed that ILBI contributes to the development
of connective tissue, causes earlier normalization of pulse activity and quickens
regeneration processes of a damaged nerve.
Besides, on the basis of in-depth study of the mechanisms of the influence of
intravenous laser blood irradiation on the principal manifestations of atherosclerotic
process depending on the degree of its manifestation there will be developed special
techniques, which allow determining the regimes of the radiation of whole blood
and vascular walls (intensity and duration of laser radiation, frequency and time of
influence), and provide the best therapeutic effect. It was shown that the developed
speckle-optical methods reflecting biophysical processes in capillary skin channel are
applicable for the estimation of microhemodynamics of human skin during vertebral
pathology. The studies of microhemodynamics of human skin in different functional
states both in separate points and in skin areas of 40 × 55 mm
2 were conducted with
the help of laser specklometer. Microhemodynamic maps of skin areas under study
were built on the basis of the measurements.
11. The studies of the change of the concentration of oxyhemoglobin of surface
blood flow in different functional states of skin were conducted, and a new
spectrometric method of determining the degree of ischemia of human organs
and tissues according to the change of the concentration of oxyhemoglobin of
skin was suggested. The dependence of the local extremums of spectral curve of
the reflection coefficients of skin on the level of concentration of oxyhemoglobin
of surface blood flow and the degree of ischemia was found.
Spectral properties of radiation scattered by human skin in the range of 200–700
nm were studied.
On the basis of experimental studies conducted with the help of three-wave long
spectrophotometer method, it was found out that during the traumatic damage of
peripheral nervous system in experimental animals ILBI leads to the changes of
the calculated coefficients to 30 and 37% that correspond to the difference between
ratios of amplitudes of local extremums of absorption spectrums of native blood
preparations at wavelengths of 542, 560 and 577 nm to the concentration of protein
5 Laser Specklometer, Speckle-Optical Diagnostics and Laser …
same time that creates the most favorable conditions for the regeneration of fibrous
tissues.
High sensitivity of speckle-optical methods of regeneration of hemodynamic
disorders in microcirculatory channel of skin was registered. Dealing with animals
suffering from occlusion of femoral artery progressive decrease of power of spectrum
of fluctuation intensity of speckle-field was observed in comparison with the norm
by 41–67% depending in terms of the operation that is connected with considerable
vasomotor disorders.
A considerable decrease of power spectrum of skin blood flow at the operated
limb during traumatic damage of sciatic nerve with further neurography by 67.3% in
the transmission band of 0–2000 Hz in comparison with intact group was detected.
According to the results of the conducted studies on animals, the application of
intravenous laser blood irradiation ILBI at traumatic damages of peripheral nervous
system decreases trophic disturbances, postponing the time of their appearing in
general. Morphological studies showed that ILBI contributes to the development
of connective tissue, causes earlier normalization of pulse activity and quickens
regeneration processes of a damaged nerve.
Besides, on the basis of in-depth study of the mechanisms of the influence of
intravenous laser blood irradiation on the principal manifestations of atherosclerotic
process depending on the degree of its manifestation there will be developed special
techniques, which allow determining the regimes of the radiation of whole blood
and vascular walls (intensity and duration of laser radiation, frequency and time of
influence), and provide the best therapeutic effect. It was shown that the developed
speckle-optical methods reflecting biophysical processes in capillary skin channel are
applicable for the estimation of microhemodynamics of human skin during vertebral
pathology. The studies of microhemodynamics of human skin in different functional
states both in separate points and in skin areas of 40 × 55 mm
2 were conducted with
the help of laser specklometer. Microhemodynamic maps of skin areas under study
were built on the basis of the measurements.
11. The studies of the change of the concentration of oxyhemoglobin of surface
blood flow in different functional states of skin were conducted, and a new
spectrometric method of determining the degree of ischemia of human organs
and tissues according to the change of the concentration of oxyhemoglobin of
skin was suggested. The dependence of the local extremums of spectral curve of
the reflection coefficients of skin on the level of concentration of oxyhemoglobin
of surface blood flow and the degree of ischemia was found.
Spectral properties of radiation scattered by human skin in the range of 200–700
nm were studied.
On the basis of experimental studies conducted with the help of three-wave long
spectrophotometer method, it was found out that during the traumatic damage of
peripheral nervous system in experimental animals ILBI leads to the changes of
the calculated coefficients to 30 and 37% that correspond to the difference between
ratios of amplitudes of local extremums of absorption spectrums of native blood
preparations at wavelengths of 542, 560 and 577 nm to the concentration of protein