482
5 Laser Specklometer, Speckle-Optical Diagnostics and Laser …
processes, were accompanied by the lowering of skin temperature and change of
the frequency of fluctuations spectra. On the contrary, during unchangeable regional
blood flow (at the intact limb) and absence of vegetative changes such as disorders of
the thermoregulation, a shift of frequency spectra of fluctuations into high-frequency
area was observed. Consequently, the increase of the intensity of blood supply of
covering tissues and growth of the volume of sanguiferous microcirculatory blood
channel find its reflection in the increase of the impact of high frequencies into the
spectrum of fluctuations of the intensity of speckle-field. The same fact is indicated by
the lowering asymmetry coefficient of spectrum relative to the average frequency. The
proof of this data was found in the results of the experiment with artificially caused
hyperemia of limited areas of skin of a hand, where in the area of applying irritative
agent a burst of the most high-frequency fluctuation spectra, which correspond to
the points of the most intensive microhemodynamic changes, was observed.
It is important to point out that during the study of skin microhemodynamics proximo-distal gradient of speckle-optical indicators in patients with polyneuropathies, which correlates with the changes of skin temperature and the data of
thermal imaging observation, was detected.
It was found out that in patients with neurological diseases and in animals with
damages of peripheral nervous system the course application of the method of intravenous laser blood irradiation mobilizes the system of neurohumoral regulation,
stimulating hypophysis and adrenals, thyroid and thyroid glands; has immunomodulatory effect on the organism; affects the structure of membranes of erythrocytes and
white blood cell part of the blood positively; and increases the level of hemoglobin
and the number of erythrocytes. The clinical effect of ILBI correlates with the
lowering of the activity of system of lipid peroxidation, and antioxidant system
activates; the evidence of vertebral syndrome decreases, and rebuilding of sensory
and motional function of nervous system accelerates. It is shown that ILBI stimulates
the regeneration of damaged peripheral nerve after neurography (in the experiment).
It was detected that conducting the course of intravenous laser blood irradiation by
emission of He–Ne laser in the early post-operational period in patients with traumatic
damages of peripheral nerves activates skin microhemodynamics that is manifested
by the increase of average frequency of fluctuations of the intensity of speckle-field,
formed by the scattered radiation of skin. It was shown that the therapeutic ILBI
effect is more evident on the damaged limb; however, low-intensity laser irradiation
caused the increase of skin microhemodynamics also at the healthy limb.
Differences of fluctuation intensity spectra of laser radiation on diseased and
healthy limbs were detected. Specklograms were presented, which had been detected
in patient suffered from vertebrogenit radiculitis with the damage of a root. In the
zone of innervation of mainly this root at the back surface of lower third of a crus, the
most obvious asymmetry of indicators under study is observed, while the difference
in the conditions of surface blood flow on the diseased and healthy side in other
points is either less obvious (the area of a thumb) or is absent at all (the front surface
of lower third of a hip).
Thereby, the revealed physical parameters of spectra of fluctuations of intensity
of dynamic speckle-field are characterized as physiological and pathologic changes
5 Laser Specklometer, Speckle-Optical Diagnostics and Laser …
processes, were accompanied by the lowering of skin temperature and change of
the frequency of fluctuations spectra. On the contrary, during unchangeable regional
blood flow (at the intact limb) and absence of vegetative changes such as disorders of
the thermoregulation, a shift of frequency spectra of fluctuations into high-frequency
area was observed. Consequently, the increase of the intensity of blood supply of
covering tissues and growth of the volume of sanguiferous microcirculatory blood
channel find its reflection in the increase of the impact of high frequencies into the
spectrum of fluctuations of the intensity of speckle-field. The same fact is indicated by
the lowering asymmetry coefficient of spectrum relative to the average frequency. The
proof of this data was found in the results of the experiment with artificially caused
hyperemia of limited areas of skin of a hand, where in the area of applying irritative
agent a burst of the most high-frequency fluctuation spectra, which correspond to
the points of the most intensive microhemodynamic changes, was observed.
It is important to point out that during the study of skin microhemodynamics proximo-distal gradient of speckle-optical indicators in patients with polyneuropathies, which correlates with the changes of skin temperature and the data of
thermal imaging observation, was detected.
It was found out that in patients with neurological diseases and in animals with
damages of peripheral nervous system the course application of the method of intravenous laser blood irradiation mobilizes the system of neurohumoral regulation,
stimulating hypophysis and adrenals, thyroid and thyroid glands; has immunomodulatory effect on the organism; affects the structure of membranes of erythrocytes and
white blood cell part of the blood positively; and increases the level of hemoglobin
and the number of erythrocytes. The clinical effect of ILBI correlates with the
lowering of the activity of system of lipid peroxidation, and antioxidant system
activates; the evidence of vertebral syndrome decreases, and rebuilding of sensory
and motional function of nervous system accelerates. It is shown that ILBI stimulates
the regeneration of damaged peripheral nerve after neurography (in the experiment).
It was detected that conducting the course of intravenous laser blood irradiation by
emission of He–Ne laser in the early post-operational period in patients with traumatic
damages of peripheral nerves activates skin microhemodynamics that is manifested
by the increase of average frequency of fluctuations of the intensity of speckle-field,
formed by the scattered radiation of skin. It was shown that the therapeutic ILBI
effect is more evident on the damaged limb; however, low-intensity laser irradiation
caused the increase of skin microhemodynamics also at the healthy limb.
Differences of fluctuation intensity spectra of laser radiation on diseased and
healthy limbs were detected. Specklograms were presented, which had been detected
in patient suffered from vertebrogenit radiculitis with the damage of a root. In the
zone of innervation of mainly this root at the back surface of lower third of a crus, the
most obvious asymmetry of indicators under study is observed, while the difference
in the conditions of surface blood flow on the diseased and healthy side in other
points is either less obvious (the area of a thumb) or is absent at all (the front surface
of lower third of a hip).
Thereby, the revealed physical parameters of spectra of fluctuations of intensity
of dynamic speckle-field are characterized as physiological and pathologic changes