Preface
Over the past few decades, biological microelectro-mechanical systems (BioMEMS)
have been commonly designed, fabricated, and used for a wide range of applications including cell studies, therapeutics, tissue engineering, drug delivery, implantable
devices, and biosensors, among others. BioMEMS are portable, low-cost, rapid, and
robust platforms designed to automate one or more analysis steps such as mixing,
separation, sedimentation, etc. into one monolithic device. BioMEMS have proven to be
excellent candidates for biosensing applications. Such devices act as miniaturized laboratory systems that can be used in remote and/or rural areas for detection of multiple
analytes with minimal human involvement, which, in turn, makes the detection procedure of fatal diseases safer for laboratory technicians. This book is dedicated to the latest
advancements of BioMEMS in biosensing applications. Different detection strategies
including colorimetric, fluorescence, luminescence, bioluminescence, chemiluminescence, biochemiluminescence, and electrochemiluminescence are thoroughly reviewed
in this book, and different types of BioMEMS designed and fabricated for the mentioned
detection strategies are presented with recent examples. These BioMEMS devices
include paper-based, microfluidics such as lab-on-chip (LOC), lab-on-compact-disk
(LOCD) systems and interesting alternative techniques that offer new solutions. This
book also provides an overview on the history of BioMEMS and the pioneered devices in the history of science which were designed and fabricated for different purposes.
Monterrey, Mexico
Samira Hosseini
Ricardo Garcia-Ramirez
Michelle Alejandra Espinosa-Hernandez
Sofia Reveles-Huizar
Luis Acosta-Soto
Ana Sofia Cerda-Kipper
Acknowledgements The authors would like to acknowledge the financial and technical support of
Writing Lab, TecLabs, Tecnologico de Monterrey, in the production of this work. The authors
would also like to acknowledge the kind support of Dr. Aida Rodriquez-Garcia and Mrs. Niousha
Mousavi in editing this work.
v
Over the past few decades, biological microelectro-mechanical systems (BioMEMS)
have been commonly designed, fabricated, and used for a wide range of applications including cell studies, therapeutics, tissue engineering, drug delivery, implantable
devices, and biosensors, among others. BioMEMS are portable, low-cost, rapid, and
robust platforms designed to automate one or more analysis steps such as mixing,
separation, sedimentation, etc. into one monolithic device. BioMEMS have proven to be
excellent candidates for biosensing applications. Such devices act as miniaturized laboratory systems that can be used in remote and/or rural areas for detection of multiple
analytes with minimal human involvement, which, in turn, makes the detection procedure of fatal diseases safer for laboratory technicians. This book is dedicated to the latest
advancements of BioMEMS in biosensing applications. Different detection strategies
including colorimetric, fluorescence, luminescence, bioluminescence, chemiluminescence, biochemiluminescence, and electrochemiluminescence are thoroughly reviewed
in this book, and different types of BioMEMS designed and fabricated for the mentioned
detection strategies are presented with recent examples. These BioMEMS devices
include paper-based, microfluidics such as lab-on-chip (LOC), lab-on-compact-disk
(LOCD) systems and interesting alternative techniques that offer new solutions. This
book also provides an overview on the history of BioMEMS and the pioneered devices in the history of science which were designed and fabricated for different purposes.
Monterrey, Mexico
Samira Hosseini
Ricardo Garcia-Ramirez
Michelle Alejandra Espinosa-Hernandez
Sofia Reveles-Huizar
Luis Acosta-Soto
Ana Sofia Cerda-Kipper
Acknowledgements The authors would like to acknowledge the financial and technical support of
Writing Lab, TecLabs, Tecnologico de Monterrey, in the production of this work. The authors
would also like to acknowledge the kind support of Dr. Aida Rodriquez-Garcia and Mrs. Niousha
Mousavi in editing this work.
v