270
J. C. B. Jacobsen and C. Aalkjær
In summary, there seem to be some evidence suggesting that vasomotion and
the derived flowmotion can expand the pressure range over which a heterogeneous
network can supply the surrounding tissue with sufficient flow.
References
1. C. Aalkjaer, H. Nilsson, Vasomotion: Cellular background for the oscillator and for the
synchronization of smooth muscle cells. Br. J. Pharmacol. 144(5), 605–616 (2005)
2. C. Aalkjaer, D. Boedtkjer, V. Matchkov, Vasomotion—what is currently thought? Acta. Physiol.
(Oxf). 202(3), 253–269 (2011)
3. H. Achakri, N. Stergiopulos, N. Hoogerwerf, D. Hayoz, H.R. Brunner, J.J. Meister, Intraluminal
pressure modulates the magnitude and the frequency of induced vasomotion in rat arteries. J.
Vasc. Res. 32(4), 237–246 (1995)
4. L. Bernardi, M. Rossi, S. Leuzzi, E. Mevio, G. Fornasari, A. Calciati, et al., Reduction of 0.1
Hz microcirculatory fluctuations as evidence of sympathetic dysfunction in insulin-dependent
diabetes. Cardiovasc. Res. 34(1), 185–191 (1997)
5. T. Broegger, J.C. Jacobsen, D.V. Secher, D.M. Boedtkjer, H. Kold-Petersen, F.S. Pedersen,
et al. Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric
small arteries. Cardiovasc. Res. 91(4), 685–693 (2011)
6. C.W. Chen, C.H. Lee, T.R. Hsiue, H.Y. Chang, Vasomotion in rat diaphragm microcirculation
at rest and during stepwise arterial pressure reduction. Acta. Physiol. Scand. 161(3), 281–288
(1997)
7. V. Dam, D.B. Boedtkjer, J. Nyvad, C. Aalkjaer, V. Matchkov, TMEM16A knockdown abrogates
two different Ca2+-activated Cl− currents and contractility of smooth muscle in rat mesenteric
small arteries. Pflugers Arch. Eur. J. Physiol. 466(7), 1391–1409 (2014)
8. J.E. Damber, O. Lindahl, G. Selstam, T. Tenland, Rhythmical oscillations in rat testicular
microcirculation as recorded by laser Doppler flowmetry. Acta. Physiol. Scand. 118(2), 117–
123 (1983)
9. P.Y. der Weid, J.L. Beny, Simultaneous oscillations in the membrane potential of pig coronary
artery endothelial and smooth muscle cells. J. Physiol. 471, 13–24 (1993)
10. L.Y. Di Marco, E. Farkas, C. Martin, A. Venneri, A.F. Frangi, Is Vasomotion in cerebral arteries
impaired in Alzheimer’s disease? J. Alzhe. Dis. JAD 46(1), 35–53 (2015)
11. K. Fujii, D.D. Heistad, F.M. Faraci, Vasomotion of basilar arteries in vivo. Am. J. Physiol.
258(6 Pt 2), H1829–H1834 (1990)
12. P. Gaehtgens, Why networks? Int. J. Microcirc. Clin. Exp. 11(2), 123–132 (1992)
13. C.J. Garland, Influence of the endothelium and alpha-adrenoreceptor antagonists on responses
to noradrenaline in the rabbit basilar artery. J. Physiol. 418, 205–217 (1989)
14. R. Gerstberger, J.U. Meyer, R. Rettig, M. Printz, M. Intaglietta, Regulatory role of vasoactive
peptides in subcutaneous skin microcirculation of the hamster. Int. J. Microcirc. Clin. Exp.
7(1), 3–14 (1988)
15. D. Goldman, A.S. Popel, A computational study of the effect of vasomotion on oxygen transport
from capillary networks. J. Theor. Biol. 209(2), 189–199 (2001)
16. T.M. Griffith, D.H. Edwards, Mechanisms underlying chaotic vasomotion in isolated resistance
arteries: roles of calcium and EDRF. Biorheology 30(5–6), 333–347 (1993)
17. H. Gustafsson, Vasomotion and underlying mechanisms in small arteries. An in vitro study of
rat blood vessels. Acta. Physiol. Scand. 149(Suppl. 614), 1–44 (1993)
18. H. Gustafsson, H. Nilsson, Rhythmic contractions of isolated small arteries from rat: role of
calcium. Acta. Physiol. Scand. 149(3), 283–291 (1993)
19. H. Gustafsson, M.J. Mulvany, H. Nilsson, Rhythmic contractions of isolated small arteries
from rat: influence of the endothelium. Acta. Physiol. Scand. 148, 153–163 (1993)
J. C. B. Jacobsen and C. Aalkjær
In summary, there seem to be some evidence suggesting that vasomotion and
the derived flowmotion can expand the pressure range over which a heterogeneous
network can supply the surrounding tissue with sufficient flow.
References
1. C. Aalkjaer, H. Nilsson, Vasomotion: Cellular background for the oscillator and for the
synchronization of smooth muscle cells. Br. J. Pharmacol. 144(5), 605–616 (2005)
2. C. Aalkjaer, D. Boedtkjer, V. Matchkov, Vasomotion—what is currently thought? Acta. Physiol.
(Oxf). 202(3), 253–269 (2011)
3. H. Achakri, N. Stergiopulos, N. Hoogerwerf, D. Hayoz, H.R. Brunner, J.J. Meister, Intraluminal
pressure modulates the magnitude and the frequency of induced vasomotion in rat arteries. J.
Vasc. Res. 32(4), 237–246 (1995)
4. L. Bernardi, M. Rossi, S. Leuzzi, E. Mevio, G. Fornasari, A. Calciati, et al., Reduction of 0.1
Hz microcirculatory fluctuations as evidence of sympathetic dysfunction in insulin-dependent
diabetes. Cardiovasc. Res. 34(1), 185–191 (1997)
5. T. Broegger, J.C. Jacobsen, D.V. Secher, D.M. Boedtkjer, H. Kold-Petersen, F.S. Pedersen,
et al. Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric
small arteries. Cardiovasc. Res. 91(4), 685–693 (2011)
6. C.W. Chen, C.H. Lee, T.R. Hsiue, H.Y. Chang, Vasomotion in rat diaphragm microcirculation
at rest and during stepwise arterial pressure reduction. Acta. Physiol. Scand. 161(3), 281–288
(1997)
7. V. Dam, D.B. Boedtkjer, J. Nyvad, C. Aalkjaer, V. Matchkov, TMEM16A knockdown abrogates
two different Ca2+-activated Cl− currents and contractility of smooth muscle in rat mesenteric
small arteries. Pflugers Arch. Eur. J. Physiol. 466(7), 1391–1409 (2014)
8. J.E. Damber, O. Lindahl, G. Selstam, T. Tenland, Rhythmical oscillations in rat testicular
microcirculation as recorded by laser Doppler flowmetry. Acta. Physiol. Scand. 118(2), 117–
123 (1983)
9. P.Y. der Weid, J.L. Beny, Simultaneous oscillations in the membrane potential of pig coronary
artery endothelial and smooth muscle cells. J. Physiol. 471, 13–24 (1993)
10. L.Y. Di Marco, E. Farkas, C. Martin, A. Venneri, A.F. Frangi, Is Vasomotion in cerebral arteries
impaired in Alzheimer’s disease? J. Alzhe. Dis. JAD 46(1), 35–53 (2015)
11. K. Fujii, D.D. Heistad, F.M. Faraci, Vasomotion of basilar arteries in vivo. Am. J. Physiol.
258(6 Pt 2), H1829–H1834 (1990)
12. P. Gaehtgens, Why networks? Int. J. Microcirc. Clin. Exp. 11(2), 123–132 (1992)
13. C.J. Garland, Influence of the endothelium and alpha-adrenoreceptor antagonists on responses
to noradrenaline in the rabbit basilar artery. J. Physiol. 418, 205–217 (1989)
14. R. Gerstberger, J.U. Meyer, R. Rettig, M. Printz, M. Intaglietta, Regulatory role of vasoactive
peptides in subcutaneous skin microcirculation of the hamster. Int. J. Microcirc. Clin. Exp.
7(1), 3–14 (1988)
15. D. Goldman, A.S. Popel, A computational study of the effect of vasomotion on oxygen transport
from capillary networks. J. Theor. Biol. 209(2), 189–199 (2001)
16. T.M. Griffith, D.H. Edwards, Mechanisms underlying chaotic vasomotion in isolated resistance
arteries: roles of calcium and EDRF. Biorheology 30(5–6), 333–347 (1993)
17. H. Gustafsson, Vasomotion and underlying mechanisms in small arteries. An in vitro study of
rat blood vessels. Acta. Physiol. Scand. 149(Suppl. 614), 1–44 (1993)
18. H. Gustafsson, H. Nilsson, Rhythmic contractions of isolated small arteries from rat: role of
calcium. Acta. Physiol. Scand. 149(3), 283–291 (1993)
19. H. Gustafsson, M.J. Mulvany, H. Nilsson, Rhythmic contractions of isolated small arteries
from rat: influence of the endothelium. Acta. Physiol. Scand. 148, 153–163 (1993)