542
V. S. Simi et al.
Fig. 22 3D images obtained from FESEM images for single nanotube (a) TNT and ta-C filled TNT
samples at (b) 0.5 min, (c) 1 min, (d) 2 min, (e) 5 min and (f) 10 min (Republished with permission
of the Royal Society of Chemistry, from Mohan et al. [130])
(drug-releasing implants) is capable of application in several areas, such as minimize the inflammatory reactions, bone infections treatment, progress and support of
bone healing, osseointegration enhancement, and narrow treatment of bone cancers.
The TNT formed on Ti-6Al-7Nb (30 V) was filled with biopolymer chitosan
[135]. 0.2 ml of chitosan was filled on the top of the quercetin filled nanotubes at
various concentrations 0.5, 1 and 2% 0.10 mg of quercetin was dissolved in 0.2 ml
of ethanol and incorporated into nanotubes by top filling method. FESEM images of
the TNT filled with chitosan with different concentrations are shown in Fig. 23.
The filling of TNT with polymer was verified using 3D analysis. The 3D images
of the polymer filled TNT obtained from the FESEM images are shown in Fig. 24.
As can be seen from the figures the filling of chitosan has taken place gradually
into the TNT. In case of 0.5%, filling of chitosan takes place in inter-tubular space
and pores. In 1%, chitosan filled into inter-tubular space and pores formed regularly
arranged pit like morphology. Similarly, in 2% chitosan filled TNT, uniform smooth
morphology can be seen which has completely covered the tubular structure.
Figure 25 show the 3D images obtained from FESEM images for single nanotube
of chitosan filled TNT samples at 0.5, 1 and 2%, respectively. Similarly, 2D profiles
for the same are also given in the figure. After chitosan filling at various concentrations, the height and diameter of the nanotube decreases with a progressive filling
of chitosan into TNT. The thickness of the chitosan filled at various concentrations
was found to be 0.6, 1 and 3 μm for 0.5, 1 and 2% chitosan, respectively. Hence,
thickness increased with an increase in chitosan concentration.
V. S. Simi et al.
Fig. 22 3D images obtained from FESEM images for single nanotube (a) TNT and ta-C filled TNT
samples at (b) 0.5 min, (c) 1 min, (d) 2 min, (e) 5 min and (f) 10 min (Republished with permission
of the Royal Society of Chemistry, from Mohan et al. [130])
(drug-releasing implants) is capable of application in several areas, such as minimize the inflammatory reactions, bone infections treatment, progress and support of
bone healing, osseointegration enhancement, and narrow treatment of bone cancers.
The TNT formed on Ti-6Al-7Nb (30 V) was filled with biopolymer chitosan
[135]. 0.2 ml of chitosan was filled on the top of the quercetin filled nanotubes at
various concentrations 0.5, 1 and 2% 0.10 mg of quercetin was dissolved in 0.2 ml
of ethanol and incorporated into nanotubes by top filling method. FESEM images of
the TNT filled with chitosan with different concentrations are shown in Fig. 23.
The filling of TNT with polymer was verified using 3D analysis. The 3D images
of the polymer filled TNT obtained from the FESEM images are shown in Fig. 24.
As can be seen from the figures the filling of chitosan has taken place gradually
into the TNT. In case of 0.5%, filling of chitosan takes place in inter-tubular space
and pores. In 1%, chitosan filled into inter-tubular space and pores formed regularly
arranged pit like morphology. Similarly, in 2% chitosan filled TNT, uniform smooth
morphology can be seen which has completely covered the tubular structure.
Figure 25 show the 3D images obtained from FESEM images for single nanotube
of chitosan filled TNT samples at 0.5, 1 and 2%, respectively. Similarly, 2D profiles
for the same are also given in the figure. After chitosan filling at various concentrations, the height and diameter of the nanotube decreases with a progressive filling
of chitosan into TNT. The thickness of the chitosan filled at various concentrations
was found to be 0.6, 1 and 3 μm for 0.5, 1 and 2% chitosan, respectively. Hence,
thickness increased with an increase in chitosan concentration.