384
N. Ashwin Kumar et al.
the pitfalls to provide a better design that helps both research and mankind. At last,
the advances in nanoprobes would lead to the development of specialized imaging
systems that helps researchers and physicians for better diagnosis and treatment for
several diseases.
References
1. Cunha L, Horvath I, Ferreira S, Lemos J, Costa P, Vieira D, Veres DS, Szigeti K, Summavielle
T, Mathe D, Metello LF (2014) Preclinical imaging: an essentially in modern biosciences.
Mol Diagn Ther 18(2):153–173. https://doi.org/10.1007/s40291-013-0062-3
2. Malikova MA (2016) Optimization of protocol design: a path to efficient, lower cost clinical
trial execution. Future Sci OA 2(1):FSO89. https://doi.org/10.4155/fso.15.89
3. Bushberg JT, Seibert JA, Leidholdt EM, Boone JM (2011) The essential physics of medical
imaging. Wolters Kluwer Health
4. Nune SK, Gunda P, Thallapally PK, Lin YY, Forrest ML, Berkland CJ (2009) Nanoparticles
for biomedical imaging. Expert Opin Drug Deliv 6(11):1175–1194. https://doi.org/10.1517/
17425240903229031
5. McNamara K, Tofail SAM (2016) Nanoparticles in biomedical applications. Adv Phys: X
2(1):54–88. https://doi.org/10.1080/23746149.2016.1254570
6. Smith BR, Gambhir SS (2017) Nanomaterials for in vivo imaging. Chem Rev 117(3):901–986.
https://doi.org/10.1021/acs.chemrev.6b00073
7. Yao R, Lecomte R, Crawford ES (2012) Small-animal PET: what is it, and why do we need
it? J Nucl Med Technol 40(3):157–165. https://doi.org/10.2967/jnmt.111.098632
8. Yang DJ, Kim EE, Inoue T (2006) Targeted molecular imaging in oncology. Ann Nucl Med
20(1):1–11. https://doi.org/10.1007/bf02985584
9. Exner DV, Kavanagh KM, Slawnych MP, Mitchell LB, Ramadan D, Aggarwal SG, Noullett
C, Van Schaik A, Mitchell RT, Shibata MA, Gulamhussein S, McMeekin J, Tymchak W,
Schnell G, Gillis AM, Sheldon RS, Fick GH, Duff HJ, Investigators R (2007) Noninvasive
risk assessment early after a myocardial infarction the REFINE study. J Am Coll Cardiol
50(24):2275–2284. https://doi.org/10.1016/j.jacc.2007.08.042
10. Seaman ME, Contino G, Bardeesy N, Kelly KA (2010) Molecular imaging agents: impact
on diagnosis and therapeutics in oncology. Expert Rev Mol Med 12:e20. https://doi.org/10.
1017/S1462399410001511
11. Pysz MA, Gambhir SS, Willmann JK (2010) Molecular imaging: current status and emerging
strategies. Clin Radiol 65(7):500–516. https://doi.org/10.1016/j.crad.2010.03.011
12. Kim D, Kim J, Park YI, Lee N, Hyeon T (2018) Recent development of inorganic nanoparticles
for biomedical imaging. ACS Cent Sci 4(3):324–336. https://doi.org/10.1021/acscentsci.7b0
0574
13. Nagai M, Kato K, Soga S, Santra TS, Shibata T (2020) Scalable parallel manipulation
of single cells using micronozzle array integrated with bidirectional electrokinetic pumps.
Micromachines (Basel) 11(4). https://doi.org/10.3390/mi11040442
14. Peixoto L, Magalhães R, Navas D, Moraes S, Redondo C, Morales R, Araújo JP, Sousa
CT (2020) Magnetic nanostructures for emerging biomedical applications. Appl Phys Rev
7(1):011310. https://doi.org/10.1063/1.5121702
15. Arms L, Smith DW, Flynn J, Palmer W, Martin A, Woldu A, Hua S (2018) Advantages
and limitations of current techniques for analyzing the biodistribution of nanoparticles. Front
Pharm 9:802. https://doi.org/10.3389/fphar.2018.00802
16. Dong YC, Hajfathalian M, Maidment PSN, Hsu JC, Naha PC, Si-Mohamed S, Breuilly M,
Kim J, Chhour P, Douek P, Litt HI, Cormode DP (2019) Effect of gold nanoparticle size on
their properties as contrast agents for computed tomography. Sci Rep 9(1):14912. https://doi.
org/10.1038/s41598-019-50332-8
N. Ashwin Kumar et al.
the pitfalls to provide a better design that helps both research and mankind. At last,
the advances in nanoprobes would lead to the development of specialized imaging
systems that helps researchers and physicians for better diagnosis and treatment for
several diseases.
References
1. Cunha L, Horvath I, Ferreira S, Lemos J, Costa P, Vieira D, Veres DS, Szigeti K, Summavielle
T, Mathe D, Metello LF (2014) Preclinical imaging: an essentially in modern biosciences.
Mol Diagn Ther 18(2):153–173. https://doi.org/10.1007/s40291-013-0062-3
2. Malikova MA (2016) Optimization of protocol design: a path to efficient, lower cost clinical
trial execution. Future Sci OA 2(1):FSO89. https://doi.org/10.4155/fso.15.89
3. Bushberg JT, Seibert JA, Leidholdt EM, Boone JM (2011) The essential physics of medical
imaging. Wolters Kluwer Health
4. Nune SK, Gunda P, Thallapally PK, Lin YY, Forrest ML, Berkland CJ (2009) Nanoparticles
for biomedical imaging. Expert Opin Drug Deliv 6(11):1175–1194. https://doi.org/10.1517/
17425240903229031
5. McNamara K, Tofail SAM (2016) Nanoparticles in biomedical applications. Adv Phys: X
2(1):54–88. https://doi.org/10.1080/23746149.2016.1254570
6. Smith BR, Gambhir SS (2017) Nanomaterials for in vivo imaging. Chem Rev 117(3):901–986.
https://doi.org/10.1021/acs.chemrev.6b00073
7. Yao R, Lecomte R, Crawford ES (2012) Small-animal PET: what is it, and why do we need
it? J Nucl Med Technol 40(3):157–165. https://doi.org/10.2967/jnmt.111.098632
8. Yang DJ, Kim EE, Inoue T (2006) Targeted molecular imaging in oncology. Ann Nucl Med
20(1):1–11. https://doi.org/10.1007/bf02985584
9. Exner DV, Kavanagh KM, Slawnych MP, Mitchell LB, Ramadan D, Aggarwal SG, Noullett
C, Van Schaik A, Mitchell RT, Shibata MA, Gulamhussein S, McMeekin J, Tymchak W,
Schnell G, Gillis AM, Sheldon RS, Fick GH, Duff HJ, Investigators R (2007) Noninvasive
risk assessment early after a myocardial infarction the REFINE study. J Am Coll Cardiol
50(24):2275–2284. https://doi.org/10.1016/j.jacc.2007.08.042
10. Seaman ME, Contino G, Bardeesy N, Kelly KA (2010) Molecular imaging agents: impact
on diagnosis and therapeutics in oncology. Expert Rev Mol Med 12:e20. https://doi.org/10.
1017/S1462399410001511
11. Pysz MA, Gambhir SS, Willmann JK (2010) Molecular imaging: current status and emerging
strategies. Clin Radiol 65(7):500–516. https://doi.org/10.1016/j.crad.2010.03.011
12. Kim D, Kim J, Park YI, Lee N, Hyeon T (2018) Recent development of inorganic nanoparticles
for biomedical imaging. ACS Cent Sci 4(3):324–336. https://doi.org/10.1021/acscentsci.7b0
0574
13. Nagai M, Kato K, Soga S, Santra TS, Shibata T (2020) Scalable parallel manipulation
of single cells using micronozzle array integrated with bidirectional electrokinetic pumps.
Micromachines (Basel) 11(4). https://doi.org/10.3390/mi11040442
14. Peixoto L, Magalhães R, Navas D, Moraes S, Redondo C, Morales R, Araújo JP, Sousa
CT (2020) Magnetic nanostructures for emerging biomedical applications. Appl Phys Rev
7(1):011310. https://doi.org/10.1063/1.5121702
15. Arms L, Smith DW, Flynn J, Palmer W, Martin A, Woldu A, Hua S (2018) Advantages
and limitations of current techniques for analyzing the biodistribution of nanoparticles. Front
Pharm 9:802. https://doi.org/10.3389/fphar.2018.00802
16. Dong YC, Hajfathalian M, Maidment PSN, Hsu JC, Naha PC, Si-Mohamed S, Breuilly M,
Kim J, Chhour P, Douek P, Litt HI, Cormode DP (2019) Effect of gold nanoparticle size on
their properties as contrast agents for computed tomography. Sci Rep 9(1):14912. https://doi.
org/10.1038/s41598-019-50332-8