Biomedical Applications of Carbon-Based Nanomaterials
173
46. Foley S, Crowley C, Smaihi M, Bonfils C, Erlanger BF, Seta P, Larroque C (2002) Cellular
localisation of a water-soluble fullerene derivative. Biochem Biophys Res Commun 294:116–
119
47. Isobe H, Tomita N, Jinno S, Okayama H, Nakamura E (2001) Synthesis and transfection
capability of multi-functionalized fullerene polyamine. Chem Lett 12:1214–1215
48. Rouse JG, Yang J, Ryman-Rasmussen JP, Barron AR, Monteiro-Riviere NA (2007) Effects of
mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles
through the skin. Nano Lett 7:155–160
49. Mori T, Takada H, Ito S, Matsubayashi K, Miwa N, Sawaguchi T (2006) Preclinical studies
on the safety of fullerene upon acute oral administration and evaluation for no mutagenesis.
Toxicology 225:48–54
50. Thrash TP, Cagle DW, Alford JM, Wright K, Ehrhardt GJ, Mirzadeh S, Wilson LJ (1999)
Toward fullerene-based radiopharmaceuticals: high-yield neutron activation of endohedral
165Ho metallofullerenes. Chem Phys Lett 308:329–336
51. Yamakoshi Y, Umezawa N, Ryu A, Arakane K, Miyata N, Goda Y, Masumizu T, Nagano
T (2003) Active oxygen species generated from photoexcited fullerene (C 60 ) as potential
medicines: O-.bul.2 versus 1O2. J Am Chem Soc 125:12803–12809
52. Rancan F, Rosan S, Boehm F, Cantrell A, Brellreich M, Schoenberger H, Hirsch A, Moussa F
(2002) Cytotoxicity and photocytotoxicity of a dendritic C 60 mono-adduct and a malonic acid
C 60 tris-adduct on Jurkat cells. J Photochem Photobiol, B 67:157–162
53. Ji ZQ, Sun H, Wang H, Xie Q, Liu Y, Wang Z (2006) Biodistribution and tumour uptake of
C60(OH)x in mice. J Nanoparticle Res 8:53–63
54. Liu J, Ohta S, Sonoda A, Yamada M, Yamamoto M, Nitta N, Murata K, Tabata Y (2007)
Preparation of PEG-conjugated fullerene containing Gd 3+ ions for photodynamic therapy. J
Controll Release 117:104–110
55. Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T, Hamblin MR (2007) Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II
photochemical mechanism. Free Radical Biol Med 43:711–719
56. Semeniuk M, Yi Z, Poursorkhabi V, Tjong J, Jaffer S, Lu ZH, Sain M (2019) Future perspectives
and review on organic carbon dots in electronic applications. ACS Nano 13:6224–6255
57. Wang Y, Meng Y, Wang S, Li C, Shi W, Chen J, Wang J, Huang R (2015) Direct solventderived polymer-coated nitrogen-doped carbon nanodots with high water solubility for targeted
fluorescence imaging of glioma. Small 11:3575–3581
58. Xu Y, Chun-Jing T, Huang H, Chao-Qun S, Ya-Kun Z, Qun-Feng Y, Ai-Jun W (2014) Green
synthesis of fluorescent carbon quantum dots for detection of Hg 2+ . Chin J Anal Chem 42:1252–
1258
59. De B, Karak N (2013) A green and facile approach for the synthesis of water-soluble fluorescent
carbon dots from banana juice. RSC Adv 3:8286–8290
60. Yang X, Zhuo Y, Zhu S, Luo Y, Feng Y, Dou Y (2014) Novel and green synthesis of highfluorescent carbon dots originated from honey for sensing and imaging. Biosens Bioelectron
60:292–298
61. Wang Y, Anilkumar P, Cao L, Liu JH, Luo PG, Tackett KN, Sahu S, Wang P, Wang X, Sun YP
(2011) Carbon dots of different composition and surface functionalization: cytotoxicity issues
relevant to fluorescence cell imaging. Exp Biol Med 236:1231–1238
62. Du F, Min Y, Zeng F, Yu C, Wu S (2014) A targeted and FRET-based ratiometric fluorescent
nanoprobe for imaging mitochondrial hydrogen peroxide in living cells. Small 10:964–972
63. Weng CI, Chang HT, Lin CH, Shen YW, Unnikrishnan B, Li YJ, Hang CC (2015) One-step
synthesis of biofunctional carbon quantum dots for bacterial labelling. Biosens Bioelectron
68:1–6
64. Chen L, Song L, Zhang Y, Wang P, Xiao Z, Guo Y, Cao F (2016) Nitrogen and sulfur codoped
reduced graphene oxide as a general platform for rapid and sensitive fluorescent detection of
biological species. ACS Appl Mater Interfaces 8:11255–11261
65. Kudr J, Richtera L, Xhaxhiu K, Hynek D, Heger Z, Zirka O, Adam V (2017) Carbon dots based
FRET for the detection of DNA damage. Biosens Bioelectron 92:133–139
173
46. Foley S, Crowley C, Smaihi M, Bonfils C, Erlanger BF, Seta P, Larroque C (2002) Cellular
localisation of a water-soluble fullerene derivative. Biochem Biophys Res Commun 294:116–
119
47. Isobe H, Tomita N, Jinno S, Okayama H, Nakamura E (2001) Synthesis and transfection
capability of multi-functionalized fullerene polyamine. Chem Lett 12:1214–1215
48. Rouse JG, Yang J, Ryman-Rasmussen JP, Barron AR, Monteiro-Riviere NA (2007) Effects of
mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles
through the skin. Nano Lett 7:155–160
49. Mori T, Takada H, Ito S, Matsubayashi K, Miwa N, Sawaguchi T (2006) Preclinical studies
on the safety of fullerene upon acute oral administration and evaluation for no mutagenesis.
Toxicology 225:48–54
50. Thrash TP, Cagle DW, Alford JM, Wright K, Ehrhardt GJ, Mirzadeh S, Wilson LJ (1999)
Toward fullerene-based radiopharmaceuticals: high-yield neutron activation of endohedral
165Ho metallofullerenes. Chem Phys Lett 308:329–336
51. Yamakoshi Y, Umezawa N, Ryu A, Arakane K, Miyata N, Goda Y, Masumizu T, Nagano
T (2003) Active oxygen species generated from photoexcited fullerene (C 60 ) as potential
medicines: O-.bul.2 versus 1O2. J Am Chem Soc 125:12803–12809
52. Rancan F, Rosan S, Boehm F, Cantrell A, Brellreich M, Schoenberger H, Hirsch A, Moussa F
(2002) Cytotoxicity and photocytotoxicity of a dendritic C 60 mono-adduct and a malonic acid
C 60 tris-adduct on Jurkat cells. J Photochem Photobiol, B 67:157–162
53. Ji ZQ, Sun H, Wang H, Xie Q, Liu Y, Wang Z (2006) Biodistribution and tumour uptake of
C60(OH)x in mice. J Nanoparticle Res 8:53–63
54. Liu J, Ohta S, Sonoda A, Yamada M, Yamamoto M, Nitta N, Murata K, Tabata Y (2007)
Preparation of PEG-conjugated fullerene containing Gd 3+ ions for photodynamic therapy. J
Controll Release 117:104–110
55. Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T, Hamblin MR (2007) Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II
photochemical mechanism. Free Radical Biol Med 43:711–719
56. Semeniuk M, Yi Z, Poursorkhabi V, Tjong J, Jaffer S, Lu ZH, Sain M (2019) Future perspectives
and review on organic carbon dots in electronic applications. ACS Nano 13:6224–6255
57. Wang Y, Meng Y, Wang S, Li C, Shi W, Chen J, Wang J, Huang R (2015) Direct solventderived polymer-coated nitrogen-doped carbon nanodots with high water solubility for targeted
fluorescence imaging of glioma. Small 11:3575–3581
58. Xu Y, Chun-Jing T, Huang H, Chao-Qun S, Ya-Kun Z, Qun-Feng Y, Ai-Jun W (2014) Green
synthesis of fluorescent carbon quantum dots for detection of Hg 2+ . Chin J Anal Chem 42:1252–
1258
59. De B, Karak N (2013) A green and facile approach for the synthesis of water-soluble fluorescent
carbon dots from banana juice. RSC Adv 3:8286–8290
60. Yang X, Zhuo Y, Zhu S, Luo Y, Feng Y, Dou Y (2014) Novel and green synthesis of highfluorescent carbon dots originated from honey for sensing and imaging. Biosens Bioelectron
60:292–298
61. Wang Y, Anilkumar P, Cao L, Liu JH, Luo PG, Tackett KN, Sahu S, Wang P, Wang X, Sun YP
(2011) Carbon dots of different composition and surface functionalization: cytotoxicity issues
relevant to fluorescence cell imaging. Exp Biol Med 236:1231–1238
62. Du F, Min Y, Zeng F, Yu C, Wu S (2014) A targeted and FRET-based ratiometric fluorescent
nanoprobe for imaging mitochondrial hydrogen peroxide in living cells. Small 10:964–972
63. Weng CI, Chang HT, Lin CH, Shen YW, Unnikrishnan B, Li YJ, Hang CC (2015) One-step
synthesis of biofunctional carbon quantum dots for bacterial labelling. Biosens Bioelectron
68:1–6
64. Chen L, Song L, Zhang Y, Wang P, Xiao Z, Guo Y, Cao F (2016) Nitrogen and sulfur codoped
reduced graphene oxide as a general platform for rapid and sensitive fluorescent detection of
biological species. ACS Appl Mater Interfaces 8:11255–11261
65. Kudr J, Richtera L, Xhaxhiu K, Hynek D, Heger Z, Zirka O, Adam V (2017) Carbon dots based
FRET for the detection of DNA damage. Biosens Bioelectron 92:133–139