150
S. A. Pauline
4.5.2 Filler Material
Bioactive glass-ceramic (BCG) is widely used as filler material for regenerating
bone tissue as it can form strong interface between hard as well as soft tissue. Nanobioglass ceramic particles doped with Calcarea phosphorica were formulated and
their biological action in bone tissue engineering application was investigated [111].
Ca, Mg and Si-containing bioceramics such as calcium silicates have greater applications as they have better mechanical properties, controllable degradation rate, facilitate bone growth and aid healing [112]. Porous and non-porous calcium phosphate
glass-ceramics were synthesized and used as injectable bone cement when added
with xanthan gum for cell-based bone regeneration treatment. The possible damage
of porous calcium phosphate during injection process is prevented by xanthan gum
as a result of its viscoeleastic properties [113]. Surface pre-reacted glass is now
increasingly used to fill tooth defects in dentistry. Various types of ions such as Al
+3 ,
BO
−3 , Na
+ , SiO3
−2 , F
− , Li
+, etc., are released from these fillers and they exhibit
high antibacterial activity and enhance osteoblast differentiation [114].
5 Summary
Nanoceramic materials are finding increased applications in the field of biomaterials owing to their biocompatibility, mechanical strength and greater surface area.
They are increasingly used as implant coatings, scaffolds, bone grafts, drug delivery
devices and biosensors. The various synthesis methods of nano bioceramics are
discussed in this chapter. The characterization techniques used to study the various
aspects of nanoceramics are briefly described. Nanoceramics are widely used as
metal implant coatings to increase its functionality, bioactivity and resistance to
corrosion and wear. Nanoceramic coatings play the dual role of in situ drug delivery
system which deliver drugs directly in the implantation site and aid in faster healing
and stronger bone-implant interface establishment. As nanoceramics have greater
compressive strength and wear resistance they are successfully used as dental applications. The magnetic and radiopacity properties of nanoceramics are utilized in
diagnostics and medical imaging. The nanoceramic’s biodegradation property can
be modified by converting them into nanocomposites with biopolymeric materials
which are successfully used as scaffold materials. The application of scaffold as
implant devices is increasing owing to its ability to biodegrade and aid natural bone
growth in the defective site. Nanoceramics are being reinvented as filler materials
in tissue engineering applications and the field is gaining momentum owing to its
biocompatibility. Nanoceramics are continually implored in various capacities to
bring out its advantageous properties to build functional biomaterials.
S. A. Pauline
4.5.2 Filler Material
Bioactive glass-ceramic (BCG) is widely used as filler material for regenerating
bone tissue as it can form strong interface between hard as well as soft tissue. Nanobioglass ceramic particles doped with Calcarea phosphorica were formulated and
their biological action in bone tissue engineering application was investigated [111].
Ca, Mg and Si-containing bioceramics such as calcium silicates have greater applications as they have better mechanical properties, controllable degradation rate, facilitate bone growth and aid healing [112]. Porous and non-porous calcium phosphate
glass-ceramics were synthesized and used as injectable bone cement when added
with xanthan gum for cell-based bone regeneration treatment. The possible damage
of porous calcium phosphate during injection process is prevented by xanthan gum
as a result of its viscoeleastic properties [113]. Surface pre-reacted glass is now
increasingly used to fill tooth defects in dentistry. Various types of ions such as Al
+3 ,
BO
−3 , Na
+ , SiO3
−2 , F
− , Li
+, etc., are released from these fillers and they exhibit
high antibacterial activity and enhance osteoblast differentiation [114].
5 Summary
Nanoceramic materials are finding increased applications in the field of biomaterials owing to their biocompatibility, mechanical strength and greater surface area.
They are increasingly used as implant coatings, scaffolds, bone grafts, drug delivery
devices and biosensors. The various synthesis methods of nano bioceramics are
discussed in this chapter. The characterization techniques used to study the various
aspects of nanoceramics are briefly described. Nanoceramics are widely used as
metal implant coatings to increase its functionality, bioactivity and resistance to
corrosion and wear. Nanoceramic coatings play the dual role of in situ drug delivery
system which deliver drugs directly in the implantation site and aid in faster healing
and stronger bone-implant interface establishment. As nanoceramics have greater
compressive strength and wear resistance they are successfully used as dental applications. The magnetic and radiopacity properties of nanoceramics are utilized in
diagnostics and medical imaging. The nanoceramic’s biodegradation property can
be modified by converting them into nanocomposites with biopolymeric materials
which are successfully used as scaffold materials. The application of scaffold as
implant devices is increasing owing to its ability to biodegrade and aid natural bone
growth in the defective site. Nanoceramics are being reinvented as filler materials
in tissue engineering applications and the field is gaining momentum owing to its
biocompatibility. Nanoceramics are continually implored in various capacities to
bring out its advantageous properties to build functional biomaterials.